Experiences with

Interferon

Additional medicines such as Interferon and Thalidomide are suggested to complement the Ruxolitinib. Radiology is an option or in the worst case, having the Spleen removed surgically. I have a telephone consultation on the 19th April and will discuss the options.

After taking 135mcg of PEG Interferon since January 2020 (just over a year) my Haematocrit level is still high at 48 (all other counts are now OK - Platelets down from over 1000 to 300) My consultant wants to increase dosage to 180mcg for next two months Is anyone else taking this sort of dose ....

Interferon-alpha (IFNα) therapy is the only treatment option available that can achieve molecular remission. However, long-term treatment with IFNα is required and patients frequently exhibit adverse side-effects.

Does anyone have a definitive list of counties in the UK that prescribe peg interferon on the NHS without having to aquire funding. It's a lottery as to whether you can access this drug depending on where you live.

Over five weeks ago I have been placed on Interferon Alpha Injections. At this moment I am only taking half the dosage . Then I have to change the needle the following week and use the other half of the dosage. The needle is slightly larger than the normal needle that is in the packet.

Evidence suggests that influenza virus variants are more prevalent in pregnant and/or obese individuals due to their impaired interferon response. We have recently shown that the non-allergic, paucigranulocytic subtype of asthma is associated with impaired type I interferon production.

What type of interferon is best Has anyone been forced to return to HU because interferon did not suit them? Are there any here who had remission after using interferon How long is it best to use interferon ? Thank you in advance ....... This community here is just too good to be true almost .

which it works, then we can develop drugs that could target some of these mechanisms or potentially combine IFN with a drug that can create a synergy that ultimately would lead to a cure for the disease,” Abu-Zeinah said. » https://www.onclive.com/view/abu-zeinah-shares-next-steps-for-research-with-interferon-alpha-in-polycythemia-vera

Hi I recently started on interferon switching from Hydrea. I have ET. Since starting interferon l have been having on -going leg pain ( hip and shins) not all the time. First in my left leg then in the right. Wandered if anyone else has had the same. I take paracetamol which helps.

Here, we give an overview of the developing prognostic tools and therapeutic landscape for PV, focusing on four drug classes: pegylated interferon-alpha 2, MDM2 antagonists, hepcidin mimetics, and histone deacetylase inhibitors. » « The future of PV treatment likely will require combination treatments

Good morning, would love to hear looking from patients who have moved from Hydroxy to Interferon. I am 48 and been on hydroxy for 4 years but my consultant is now suggesting moving over to interferon.

My hematologist decided to try interferon. Starting it soon kind of scared cause I heard it causes depression and anxiety, also flu like symptoms. Anyone else experienced anything like that while on interferon?

Time on treatment analysis demonstrated that every year on interferon reduced the risk of progression to myelofibrosis (MF) by 9% (HR 0.91 [95% CI, 0.87–0.95]; p < 0.001), and was associated with a mortality risk reduction by 6% per year (HR 0.94 [95% CI, 0.90–0.99]; p < 0.012).

STING-stimulator of interferon genes is discussed below-part of the innate immune system.... https://en.wikipedia.org/wiki/Stimulator_of_interferon_genes and the article regrading the nanoparticle drug: https://www.sciencedaily.com/releases/2021/02/210208125351.htm A new radioactive bone cement is being

Should I push for getting on pegylated interferon?

I am due my interferon injection on Wednesday. Is it ok to have the interferon injection just before the vaccine injection? Many Thanks x

Hi folks Quick question; has anyone had vaccine on weekly interferon injections? If so does it present issues? Apparently people are being asked if they’ve had any injections in the last seven days. Thanks Pete

« The use of interferon for the treatment of myeloproliferative neoplasms has a long tradition.

Has anyone experienced shingles while on Pegasys interferon for essential thrombocythemia ? X

I have switched 3 times, because I dislike intensely needles, and because Interferon Beta 1 B is different from 1A and 1A does not like me. I take Tecfidera now and write this standing at my desk. As best as I can tell, I still have Relapsing-remitting ms(RRMS).