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Need to Change Treatment
So I have progression after two years on Ibrance and Letrozole. I have an opportunity to participate in a clinical trial in my town in which I would be randomly assigned to Giredestrant, a promising oral SERD (monotherapy) or both Giredestrant with a new Pikc3a drug. My standard of care option would
So I have progression after two years on Ibrance and Letrozole. I have an opportunity to participate in a clinical trial in my town in which I would be randomly assigned to Giredestrant, a promising oral SERD (monotherapy) or both Giredestrant with a new Pikc3a drug. My standard of care option would
Trissh
in
SHARE Metastatic Breast Cancer
10 months ago
always hungry
Hi, I’ve suffered from stomach issues since December 2022. The obvious stuff - bloating, constipation and then diarrhoea, minor cramps, and nausea etc. I’m in my 4th doctors appointment for the problem, and all my blood tests are clear. I’ve recently been given IBS relief tablets, but I’m hesitant
Hi, I’ve suffered from stomach issues since December 2022. The obvious stuff - bloating, constipation and then diarrhoea, minor cramps, and nausea etc. I’m in my 4th doctors appointment for the problem, and all my blood tests are clear. I’ve recently been given IBS relief tablets, but I’m hesitant
sunflower606
in
IBS Network
8 months ago
Question re: Ablation of Liver Mets
Hello! I've had liver mets - in addition to bone - for a little over a year. When I was scheduled for a biopsy of the liver (a year ago), I asked my doc if they could ablate the tumor at that time and she "found/chose" a surgeon who would do this. So it seemed to be non-routine. I received a bill
Hello! I've had liver mets - in addition to bone - for a little over a year. When I was scheduled for a biopsy of the liver (a year ago), I asked my doc if they could ablate the tumor at that time and she "found/chose" a surgeon who would do this. So it seemed to be non-routine. I received a bill
Gallivanter
in
SHARE Metastatic Breast Cancer
10 months ago
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2nd Liver Biopsy result
My 2nd liver biopsy states I have advanced bridging fibrosis with a score of 4/6. Which I think means F3. My previous fibroscan was F2 (9.2kpa). I'm not seeing my consultant for 13 weeks. I know I'm not supposed to post test results but I would love to hear from anyone at F3 & how they are coping with
My 2nd liver biopsy states I have advanced bridging fibrosis with a score of 4/6. Which I think means F3. My previous fibroscan was F2 (9.2kpa). I'm not seeing my consultant for 13 weeks. I know I'm not supposed to post test results but I would love to hear from anyone at F3 & how they are coping with
Bigbluemonkey
in
British Liver Trust
6 months ago
Lump on buttocks due to FULVESTRANT injection
My mom is diagnosed with stage 4 breast cancer .. currently she is on her hormonal therapy ..FULVESTRANT injection are injected ....the injections are injected on buttocks ..due to this there is lump on her buttocks, but its not going away , even after all the cold , hot compress..so what should i do
My mom is diagnosed with stage 4 breast cancer .. currently she is on her hormonal therapy ..FULVESTRANT injection are injected ....the injections are injected on buttocks ..due to this there is lump on her buttocks, but its not going away , even after all the cold , hot compress..so what should i do
Hidden
in
Breast Cancer India
10 months ago
Mastectomies
My partner (38) was diagnosed with stage 4 Ovarian cancer in June after many earlier chances of diagnosis. There was also a mass in one of her breasts. She had gene testing and is BRCA 1 positive. She has had 4 doses of chemo, debulking surgery (which went well) and two further doses of chemo. She
My partner (38) was diagnosed with stage 4 Ovarian cancer in June after many earlier chances of diagnosis. There was also a mass in one of her breasts. She had gene testing and is BRCA 1 positive. She has had 4 doses of chemo, debulking surgery (which went well) and two further doses of chemo. She
Kernowafibber
in
My Ovacome
10 months ago
Abdomen pain - IBS
I have suffered with IBS since for 35 years and the pain was always on the left hand side and lower bowel. Had alternating constipation and diarrhoea but managed with occasional use of fybogel. For the last couple of years however have had terrible upper abdomen pain and bloating too. Have had gastroscopy
I have suffered with IBS since for 35 years and the pain was always on the left hand side and lower bowel. Had alternating constipation and diarrhoea but managed with occasional use of fybogel. For the last couple of years however have had terrible upper abdomen pain and bloating too. Have had gastroscopy
Wobbies
in
IBS Network
8 months ago
New to this website and am looking for some advice :)
Hi, I’m a 19 year old female who has suffered from IBS my whole life, literally since I was a baby. I have EDS, PoTS, Endometriosis, GERD and Gastritis. I had H.pylori from the end of 2017 to April 2019, undiagnosed and untreated for over a year because my gp said that I was ‘attention seeking because
Hi, I’m a 19 year old female who has suffered from IBS my whole life, literally since I was a baby. I have EDS, PoTS, Endometriosis, GERD and Gastritis. I had H.pylori from the end of 2017 to April 2019, undiagnosed and untreated for over a year because my gp said that I was ‘attention seeking because
amort3ntia
in
IBS Network
8 months ago
Guardant reveal post surgery
Anyone take the blood test Guardant Reveal post stage 1 surgical removal to see if residual disease in body ? Oncologist offered - think more to ease my mind. Stage 1 a 5 1/2 years ago removed , new stage 1 a removed in October. No lymph node involvement either time. She said if positive can push for
Anyone take the blood test Guardant Reveal post stage 1 surgical removal to see if residual disease in body ? Oncologist offered - think more to ease my mind. Stage 1 a 5 1/2 years ago removed , new stage 1 a removed in October. No lymph node involvement either time. She said if positive can push for
kri312
in
The Roy Castle Lung Cancer Foundation
10 months ago
My docetaxel experience so far
For those who may be interested, I started docetaxel chemo on 20th October and have just had my 3rd infusion on 8th December. I did moderate fasting the day before for the first infusion but haven't bothered since. I wore iced gloves and socks and munched on ice cubes during the chemo sessions. I've
For those who may be interested, I started docetaxel chemo on 20th October and have just had my 3rd infusion on 8th December. I did moderate fasting the day before for the first infusion but haven't bothered since. I wore iced gloves and socks and munched on ice cubes during the chemo sessions. I've
Benkaymel
in
Advanced Prostate Cancer
10 months ago
Alendronic Acid and diverticulosis
since my Rheumy discovered I have two fractured vertebra, she is insisting I take AA. At my Dexa scan last summer AA was suggested but left to my decision as it showed ostopaenia not osteoporosis. I took AA last weekend and experienced heartburn, indigestion and difficulty and some pain swallowing. I
since my Rheumy discovered I have two fractured vertebra, she is insisting I take AA. At my Dexa scan last summer AA was suggested but left to my decision as it showed ostopaenia not osteoporosis. I took AA last weekend and experienced heartburn, indigestion and difficulty and some pain swallowing. I
Japsquar
in
PMRGCAuk
8 months ago
recurrence after lobectomy
Hello, I am 53 and live in the UK and I stop smoking in my late 20’. I had a lobectomy of my right lower lobe in April 2022 to remove a minimally invasive adenocarcinoma staged pT1 N0, M0, PL0, R0 (found by complete accident on an abdomen CT scan.) I begged for adjuvant therapy after the operation
Hello, I am 53 and live in the UK and I stop smoking in my late 20’. I had a lobectomy of my right lower lobe in April 2022 to remove a minimally invasive adenocarcinoma staged pT1 N0, M0, PL0, R0 (found by complete accident on an abdomen CT scan.) I begged for adjuvant therapy after the operation
Bibicata
in
The Roy Castle Lung Cancer Foundation
10 months ago
help with bloods.
As you will see from my previous post my daughter had been to see an endocrinologist concerning symptoms that include physical fatigue, hair loss, low moods, big thirst, migraines,itchy skin, brain fog, heart palpitation etc. He told her to take multi vitamins, vitamin D and iron . He said he’d retest
As you will see from my previous post my daughter had been to see an endocrinologist concerning symptoms that include physical fatigue, hair loss, low moods, big thirst, migraines,itchy skin, brain fog, heart palpitation etc. He told her to take multi vitamins, vitamin D and iron . He said he’d retest
WendyW1964
in
Thyroid UK
8 months ago
Rib pain after breathing test
On 22nd I took respiratory test. Ribs in area of LUNG SURGERY in 2019 are very painful upon effort; front, side, and back. I'm taking tylenol and rubbing creams with little improvement. Any one experience this after test?
On 22nd I took respiratory test. Ribs in area of LUNG SURGERY in 2019 are very painful upon effort; front, side, and back. I'm taking tylenol and rubbing creams with little improvement. Any one experience this after test?
Lyubov
in
Lung Conditions Community Forum
6 months ago
Irritable bowel and painful colon spasms
along with several other issues, limiting my mobility for long time now, at 76 , been diagnosed yr or so ago with spastic colon, so every morning for 2-3,hrs am in pain because of spasms, until able to go to bathroom 3-4 times, it s realy getting me down, recently muscle tears in gluteus and hamstring
along with several other issues, limiting my mobility for long time now, at 76 , been diagnosed yr or so ago with spastic colon, so every morning for 2-3,hrs am in pain because of spasms, until able to go to bathroom 3-4 times, it s realy getting me down, recently muscle tears in gluteus and hamstring
arvine
in
NRAS
8 months ago
Doxazosin
I have recently been prescribed Doxazosin to help with hypertension. I was concerned because one of the minor side effects is diarrhoea. I already have chronic diarrhoea due to microscopic colitis. However, the opposite seems to be happening. I have been taking 1mg daily for 9 days now. I still get the
I have recently been prescribed Doxazosin to help with hypertension. I was concerned because one of the minor side effects is diarrhoea. I already have chronic diarrhoea due to microscopic colitis. However, the opposite seems to be happening. I have been taking 1mg daily for 9 days now. I still get the
BabsyWabsy
in
IBS Network
8 months ago
Any body else like me?
Please excuse the long post, I’m hoping to pick you lovely ladies brains 💗. I was diagnosed in feb 2020 - hgs stage 3. Surgery and the usual chemo followed and then avastin for maintenance. In October ‘22 my ca125 rose gradually and a scan showed 3 lymph nodes that my oncologist didn’t think were anything
Please excuse the long post, I’m hoping to pick you lovely ladies brains 💗. I was diagnosed in feb 2020 - hgs stage 3. Surgery and the usual chemo followed and then avastin for maintenance. In October ‘22 my ca125 rose gradually and a scan showed 3 lymph nodes that my oncologist didn’t think were anything
Emmacrispins
in
My Ovacome
10 months ago
Positive ANA and Symptoms
Hi everyoneI first tested positive for ANA (high) back in 2014 think it was 1:1280 This was never really followed up & I didn't understand it as I was only young then, but in thr last 5 years I've been experiencing symptoms. I have had more blood tests just from a GP who said ANA aas positive and explained
Hi everyoneI first tested positive for ANA (high) back in 2014 think it was 1:1280 This was never really followed up & I didn't understand it as I was only young then, but in thr last 5 years I've been experiencing symptoms. I have had more blood tests just from a GP who said ANA aas positive and explained
JCM1992
in
LUPUS UK
8 months ago
Terrys nails
hi there, I’m just wondering if anyone with PBC has experience with Terrys nails? I have it on 5 of my finger nails (2 on one hand and 3 on another). My liver bloods are normal just now except for GGT (112) and my last fibroscan was 5.7 with CAP score of 233. Both AMA and ANA positive but my hepatoligist
hi there, I’m just wondering if anyone with PBC has experience with Terrys nails? I have it on 5 of my finger nails (2 on one hand and 3 on another). My liver bloods are normal just now except for GGT (112) and my last fibroscan was 5.7 with CAP score of 233. Both AMA and ANA positive but my hepatoligist
FarahS
in
PBC Foundation
8 months ago
Ibs bam
I got diagnosed with bile acid malabsorption last year January i have colesevelam for it was taking 3 a day but was getting really bad constipation, gastroenterologist said to just take 1 a day so i have been for the last few months but still getting constipation i dont eat a load of junk food i eat
I got diagnosed with bile acid malabsorption last year January i have colesevelam for it was taking 3 a day but was getting really bad constipation, gastroenterologist said to just take 1 a day so i have been for the last few months but still getting constipation i dont eat a load of junk food i eat
Netbet22
in
IBS Network
8 months ago
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