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FDA Clears IND of Intravenous JCXH-211 in Advanced Solid Tumors
The FDA has granted clearance to an investigational new drug (IND) application of intravenous (IV) JCXH-211 in patients with advanced solid tumors. JCXH-211 is a first-in-class, self-replicating mRNA (srRNA) encoding the engineered human interleukin (IL)-12 protein. With this IND, a phase 1/2 study
The FDA has granted clearance to an investigational new drug (IND) application of intravenous (IV) JCXH-211 in patients with advanced solid tumors. JCXH-211 is a first-in-class, self-replicating mRNA (srRNA) encoding the engineered human interleukin (IL)-12 protein. With this IND, a phase 1/2 study
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
palbociclib and letrozole
hi, taking palbo and letrozole for last 6 months and few days back gone for pet scan and scan response was good , many places were reduced and not much metabolic activity. So same medicines prescribed, but now suddenly in both legs nerves are paining like shooting pain heavily, will palbociclib or
hi, taking palbo and letrozole for last 6 months and few days back gone for pet scan and scan response was good , many places were reduced and not much metabolic activity. So same medicines prescribed, but now suddenly in both legs nerves are paining like shooting pain heavily, will palbociclib or
Wickey20
in
SHARE Metastatic Breast Cancer
3 months ago
Good news
I haven't written for a while , just getting on with life! But last week's news is worth reporting.The mammary lymph node they had been monitoring is now too small to report measurements. It was 9 mm last time and has further reduced. My cancer markers are better than two and a half years ago. 15-3 is
I haven't written for a while , just getting on with life! But last week's news is worth reporting.The mammary lymph node they had been monitoring is now too small to report measurements. It was 9 mm last time and has further reduced. My cancer markers are better than two and a half years ago. 15-3 is
Beryl71
in
SHARE Metastatic Breast Cancer
3 months ago
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My mother's good news
Hello ladies, I wanted to share our good news as a positive example. My mother was diagnosed with ovarian cancer staga 4a in December 2019 (you can read her story in my profile.) She had a PET scan two weeks ago and the results are good - she is stable! The doctors said she will stop taking Olaparib
Hello ladies, I wanted to share our good news as a positive example. My mother was diagnosed with ovarian cancer staga 4a in December 2019 (you can read her story in my profile.) She had a PET scan two weeks ago and the results are good - she is stable! The doctors said she will stop taking Olaparib
Uniquem
in
My Ovacome
3 months ago
21Bedlam21
I have had CLL for a couple of years now. I am on watch and wait. I have posted on this sight before. I had reconstruction from my breast cancer a number of years ago. Both sides. It looks like one side may have ruptured. I have a fast tracked appointment on Friday. I am worried sick. I know I need to
I have had CLL for a couple of years now. I am on watch and wait. I have posted on this sight before. I had reconstruction from my breast cancer a number of years ago. Both sides. It looks like one side may have ruptured. I have a fast tracked appointment on Friday. I am worried sick. I know I need to
21Bedlam21
in
CLL Support
3 months ago
Info ... Immunotherapy for Colorectal Cancer
Immunotherapy is a cancer treatment that helps the body's own immune system kill cancer cells. https://www.globalcca.org/learn/colorectal-cancer-immunotherapy
Immunotherapy is a cancer treatment that helps the body's own immune system kill cancer cells. https://www.globalcca.org/learn/colorectal-cancer-immunotherapy
GCCA-Survivor
Administrator
in
Colon Cancer Connected
3 months ago
Intratumoral Immunotherapy
Has anyone heard or and/or researched Intratumoral Immunotherapy for prostate cancer? Here's a brief description of what it is: "This treatment involves directly injecting immune-stimulating agents into the tumor, enhancing the body's immune response against cancer cells. This localized treatment activates
Has anyone heard or and/or researched Intratumoral Immunotherapy for prostate cancer? Here's a brief description of what it is: "This treatment involves directly injecting immune-stimulating agents into the tumor, enhancing the body's immune response against cancer cells. This localized treatment activates
PTvsPC
in
Prostate Cancer Network
3 months ago
initial treatment question
I am posting for my husband. He is newly diagnosed and we have spoken to the urologist/surgeon only. We were told surgery or radiation were the options. The surgeon said he would remove the prostate, seminal vesicles and 2 lymph nodes. (Said these would be teated for cancer because although the scans
I am posting for my husband. He is newly diagnosed and we have spoken to the urologist/surgeon only. We were told surgery or radiation were the options. The surgeon said he would remove the prostate, seminal vesicles and 2 lymph nodes. (Said these would be teated for cancer because although the scans
FredNick
in
Prostate Cancer Network
3 months ago
progressed on xeloda to Doxil…some fun things that happened on the way… with pictures…
I’m Beth and I am 4 years and 4 lines into this journey with the tough stuff still ahead. I am writing today to share a bit as some here have been kind enough to ask how things are going for me knowing I was having a therapy change. What a memorable month it’s been since having a small progression
I’m Beth and I am 4 years and 4 lines into this journey with the tough stuff still ahead. I am writing today to share a bit as some here have been kind enough to ask how things are going for me knowing I was having a therapy change. What a memorable month it’s been since having a small progression
Bettybuckets
in
SHARE Metastatic Breast Cancer
3 months ago
Seeking Advice for My Mom with Ovarian Cancer
Hi everyone, I'm seeking advice and opinions for my mom who has been diagnosed with ovarian cancer. The diagnosis confirmed it is aggressive. She has already undergone ovarian removal surgery and chemotherapy at a private hospital. Initially, the doctor said the first few chemotherapy sessions were
Hi everyone, I'm seeking advice and opinions for my mom who has been diagnosed with ovarian cancer. The diagnosis confirmed it is aggressive. She has already undergone ovarian removal surgery and chemotherapy at a private hospital. Initially, the doctor said the first few chemotherapy sessions were
Jasonn
in
My Ovacome
3 months ago
Lots of updates to Genetics of Prostate Cancer (PDQ®)–Health Professional Version
Genetics of Prostate Cancer •We updated information on •Executive Summary •Risk Factors for Prostate Cancer •Risk Assessment for Prostate Cancer •Indications for Prostate Cancer Germline Genetic Testing •Genetic Testing Approach for Prostate Cancer •Prostate Cancer Genetics: Screening, Surveillance
Genetics of Prostate Cancer •We updated information on •Executive Summary •Risk Factors for Prostate Cancer •Risk Assessment for Prostate Cancer •Indications for Prostate Cancer Germline Genetic Testing •Genetic Testing Approach for Prostate Cancer •Prostate Cancer Genetics: Screening, Surveillance
KocoPr
in
Advanced Prostate Cancer
3 months ago
PATIENT EXPERIENCE OF PEMBROLIZUMAB (KEYTRUDA)
PEMBOLIZUMAB (KEYTRUDA)
will shortly be assessed by the Scottish Medicine Consortium (SMC) for use in NHS Scotland with two indications: 1. In combination with platinum-based chemotherapy for the neoadjuvant (treatment given before surgery) and then continued as monotherapy (single treatment
PEMBOLIZUMAB (KEYTRUDA)
will shortly be assessed by the Scottish Medicine Consortium (SMC) for use in NHS Scotland with two indications: 1. In combination with platinum-based chemotherapy for the neoadjuvant (treatment given before surgery) and then continued as monotherapy (single treatment
RoyCastleHelpline
Roy Castle
in
The Roy Castle Lung Cancer Foundation
3 months ago
Assessing the Benefit of CAR T-cell Therapies for mCRPC
A first-in-human phase 1 trial (NCT03873805) investigated the safety and bioactivity of prostate stem cell antigen-directed CAR T cells for patients with metastatic castration-resistant prostate cancer. CancerNetwork® spoke with Saul Priceman, PhD, associate professor and associate director of the
A first-in-human phase 1 trial (NCT03873805) investigated the safety and bioactivity of prostate stem cell antigen-directed CAR T cells for patients with metastatic castration-resistant prostate cancer. CancerNetwork® spoke with Saul Priceman, PhD, associate professor and associate director of the
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
NICE early value assessment on robot-assisted surgery
Good afternoon everyone, We have been contacted by the National Institute of Health and Care Excellence (NICE) as they are currently undertaking an early value assessment on robot-assisted surgery for soft tissue procedures. We have been invited to make a submission as part of this assessment. It
Good afternoon everyone, We have been contacted by the National Institute of Health and Care Excellence (NICE) as they are currently undertaking an early value assessment on robot-assisted surgery for soft tissue procedures. We have been invited to make a submission as part of this assessment. It
OvacomeSupport
My Ovacome Team
in
My Ovacome
3 months ago
What Now?
I have been out of the hospital for about 3 days after VAT surgery. I am taking a medication and I feel nausea all the time, and even the thought of food makes me want to vomit. Is this normal? I am taking paracitomol, ibuprofin, dicloxacillin and another medication for the cough. I dont feel too
I have been out of the hospital for about 3 days after VAT surgery. I am taking a medication and I feel nausea all the time, and even the thought of food makes me want to vomit. Is this normal? I am taking paracitomol, ibuprofin, dicloxacillin and another medication for the cough. I dont feel too
VATpatient
in
Lung Cancer Support
3 months ago
My 80 year-old dad with MPCa, broke his leg and now seems to be giving up. Advice on best anti-anxiety meds desperately needed.
Dear PC family As you will see from my profile my dad in England has been on his prostate cancer journey for five years. He was doing well until March, still actively farming though fatigued, and was due to start Radium 223 in April. Sadly, he broke his leg on March 12 in a fall, was put in a full-leg
Dear PC family As you will see from my profile my dad in England has been on his prostate cancer journey for five years. He was doing well until March, still actively farming though fatigued, and was due to start Radium 223 in April. Sadly, he broke his leg on March 12 in a fall, was put in a full-leg
Lemonpower
in
Advanced Prostate Cancer
3 months ago
3mm nodule on Cardiac CT scan
On a Cardiac CT scan for my husband his internist (Not from MSK) found a nodule. This is what the impression said: "Stable 3 mm nodule in the left upper lobe, probably an impacted small airway or benign lymph node. Recommend follow-up per clinical/oncologic protocol in this patient with reported prostate
On a Cardiac CT scan for my husband his internist (Not from MSK) found a nodule. This is what the impression said: "Stable 3 mm nodule in the left upper lobe, probably an impacted small airway or benign lymph node. Recommend follow-up per clinical/oncologic protocol in this patient with reported prostate
SherryKahn
in
Advanced Prostate Cancer
3 months ago
I think we knew this - PSMA-Pet superior to MRI
PSMA PET Beats MRI in Prostate Cancer Staging Study https://www.medpagetoday.com/hematologyoncology/prostatecancer/110931 The article is basically about using PSMA-PET to plan surgical procedures more accurately, but the study has a secondary result in - that PSMA-PET found a very significant percentage
PSMA PET Beats MRI in Prostate Cancer Staging Study https://www.medpagetoday.com/hematologyoncology/prostatecancer/110931 The article is basically about using PSMA-PET to plan surgical procedures more accurately, but the study has a secondary result in - that PSMA-PET found a very significant percentage
Don_1213
in
Prostate Cancer Network
3 months ago
radiotherapy
Hi all. My husband is scheduled to have radiotherapy on Wednesday. This will hopefully stop, or at least slow down the cancer growing in his liver. He will also have radiotherapy on a hip bone which has started to cause some pain. Hopefully he will get some relief from this. I think that for now
Hi all. My husband is scheduled to have radiotherapy on Wednesday. This will hopefully stop, or at least slow down the cancer growing in his liver. He will also have radiotherapy on a hip bone which has started to cause some pain. Hopefully he will get some relief from this. I think that for now
Believeit
in
Advanced Prostate Cancer
3 months ago
Interferon
Hi everyone im on 90mg interferon every second week since Feb this year platelets were 1110 came dwn to 916 quick enough but haven't really moved dwn much since actually they went up again and now they are 876 is this the way for any of ye as it seems fairly slow to me even though my hematologist
Hi everyone im on 90mg interferon every second week since Feb this year platelets were 1110 came dwn to 916 quick enough but haven't really moved dwn much since actually they went up again and now they are 876 is this the way for any of ye as it seems fairly slow to me even though my hematologist
VTAR24
in
MPN Voice
3 months ago
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