The FDA has granted clearance to an investigational new drug (IND) application of intravenous (IV) JCXH-211 in patients with advanced solid tumors.
JCXH-211 is a first-in-class, self-replicating mRNA (srRNA) encoding the engineered human interleukin (IL)-12 protein.
With this IND, a phase 1/2 study will begin, and investigators will evaluate IV JCXH-211 for the treatment of malignant solid tumors.
Source : targetedonc.com/view/fda-cl...