Intratumoral Immunotherapy

[PTvsPC]

Has anyone heard or and/or researched Intratumoral Immunotherapy for prostate cancer? Here's a brief description of what it is:

"This treatment involves directly injecting immune-stimulating agents into the tumor, enhancing the body's immune response against cancer cells. This localized treatment activates immune cells within the tumor microenvironment, promoting the recognition and destruction of cancer cells by the immune system." (From ChatGPT)

From what I understand, multiple types of immunotherapy agents are injected directly since each person's body responds to these agents differently. Also, from what I understand, the goal isn't for the agents injected to completely kill all the cancer since it's inducing the body to learn how to identify the cancer so the body's immune response will kill it, and not just locally, but throughout the entire body. It's like a vaccine in some ways.

Any thoughts?

[dhccpa]

Provenge is the only immunotherapy approved for prostate cancer in the USA (unless you have rare mutations). At least, it seems that way to me. Others can correct me if that's incorrect.

Provenge was approved in 2010, but got off to a slow start. Still used, but less than second line ADT, chemo, etc.

[PTvsPC in reply to dhccpa]

Ok, interesting... I just recently heard about this type of treatment. I saw a video by The Williams Cancer Institute (williamscancerinstitute.com). I'm just starting to research this doctor to try to determine if this is legit.

[dhccpa in reply to PTvsPC]

Please keep us posted.

[PTvsPC in reply to dhccpa]

Will do.

[addicted2cycling]

2015 I had an in-situ injection of Keytruda+Opdivo+Yervoy in left half of prostate GL10 tumor that was cryoablated.

[PTvsPC in reply to addicted2cycling]

Was it successful? Was the cryoablation done prior to the injection?

[addicted2cycling in reply to PTvsPC]

First the cryo then months later to allow body to assimilate cryo procedure then injection. No mets and no GL 10 return yet

[PTvsPC in reply to addicted2cycling]

I'm very glad to hear that!