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Short-Course Bicalutamide with or without Bevacizumab
New study below. 6-month treatment after primary treatment failure. Seems odd to me - I wonder what they had in mind other than demonstrating an add-on benefit for bevacizumab? This statement makes no sense to me: "Patients were randomly assigned 2:1 to a luteinizing hormone-releasing hormone agonist
New study below. 6-month treatment after primary treatment failure. Seems odd to me - I wonder what they had in mind other than demonstrating an add-on benefit for bevacizumab? This statement makes no sense to me: "Patients were randomly assigned 2:1 to a luteinizing hormone-releasing hormone agonist
pjoshea13
in
Advanced Prostate Cancer
8 years ago
PC
Hi my name is Bill age 63. I have stage four PC Gleason 8 and 9. I was first diagnosed about fours years ago PSA 53. I was too late for surgery so I had radio therapy 45 sessions. I've been on Lupron from the start and went through Casodex as well. My PSA jumped to about 150+ before starting Zytiga on
Hi my name is Bill age 63. I have stage four PC Gleason 8 and 9. I was first diagnosed about fours years ago PSA 53. I was too late for surgery so I had radio therapy 45 sessions. I've been on Lupron from the start and went through Casodex as well. My PSA jumped to about 150+ before starting Zytiga on
wrando
in
Advanced Prostate Cancer
8 years ago
Targeting mTOR
mTOR is a protein with the rather whimsical name "mammalian target of rapamycin". Rapamycin (aka Sirolimus) is a bacteria discovered on Rapa Nui [Easter Island]. It inhibits mTOR. So the protein is named after the drug that inhibits it! mTOR is involved with cancer cell survival, proliferation & metastasis
mTOR is a protein with the rather whimsical name "mammalian target of rapamycin". Rapamycin (aka Sirolimus) is a bacteria discovered on Rapa Nui [Easter Island]. It inhibits mTOR. So the protein is named after the drug that inhibits it! mTOR is involved with cancer cell survival, proliferation & metastasis
pjoshea13
in
Advanced Prostate Cancer
8 years ago
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MybJourney
I was diagnosed January 20, 2014. My gleason was 9 (4+5). I had a prostatectomy in March, 2014. Unfortunately PSA didn't drop much. I decided to get colonoscopy which showed prostate cancer on my rectum. I had a prostate cancer specific contrast agent and PET scan developed at JH which showed cancer
I was diagnosed January 20, 2014. My gleason was 9 (4+5). I had a prostatectomy in March, 2014. Unfortunately PSA didn't drop much. I decided to get colonoscopy which showed prostate cancer on my rectum. I had a prostate cancer specific contrast agent and PET scan developed at JH which showed cancer
Joe32963
in
Advanced Prostate Cancer
8 years ago
Hello from uk
11 years now still here I am 73 years of age and have led an active life diagnosed in 2005 psa 4.2 gleason score 4+3=7 completed 6 months of neo adjuvant casodex followed by brachytherapy in march 2006 ,febuary 2014 psa 10.84 ct demonstrated recurrence at bladder base and seminal vesicals commenced
11 years now still here I am 73 years of age and have led an active life diagnosed in 2005 psa 4.2 gleason score 4+3=7 completed 6 months of neo adjuvant casodex followed by brachytherapy in march 2006 ,febuary 2014 psa 10.84 ct demonstrated recurrence at bladder base and seminal vesicals commenced
durango
in
Advanced Prostate Cancer
8 years ago
Xtandi, Xgeva, and Dental
Hi. Diagnosed with PC in June, 1994, Gleason 6, PSA 85.Went on intermittent hormone therapy - Lupron + Casodex -for about 14 years, which initially brought my PSA down to<0.1, but gradually became less effective.. Then tried Casodex and Avodart combo, which sort of controlled the cancer for nearly
Hi. Diagnosed with PC in June, 1994, Gleason 6, PSA 85.Went on intermittent hormone therapy - Lupron + Casodex -for about 14 years, which initially brought my PSA down to<0.1, but gradually became less effective.. Then tried Casodex and Avodart combo, which sort of controlled the cancer for nearly
lescoh
in
Advanced Prostate Cancer
8 years ago
Xtandi ?
Cost of Xtandi (enzalutamide) Diagnosed in 2000 at age 61. PSA 5.6. Radical retropubic prostatectomy. Detectable PSA 18 months post surgery. Salvage radiation 2003. PSA has continued to rise almost continuously to current level – 197.8. Have been on Lupron + Casodex for a while, then Lupron + Nilandron
Cost of Xtandi (enzalutamide) Diagnosed in 2000 at age 61. PSA 5.6. Radical retropubic prostatectomy. Detectable PSA 18 months post surgery. Salvage radiation 2003. PSA has continued to rise almost continuously to current level – 197.8. Have been on Lupron + Casodex for a while, then Lupron + Nilandron
Davisjl
in
Advanced Prostate Cancer
8 years ago
Introduction
Hi, I am here for my Dad whom was diagnosed almost 4 years ago with Stage 4 prostate Cancer, Gleason 10, PSA 32 cancer mets located in right hip, lymph nodes, T11 spine, and 2 liver lesions. At the time of diagnosis my Dad was 60 years old and is now 64. When my Dad was initially diagnosed he was experiencing
Hi, I am here for my Dad whom was diagnosed almost 4 years ago with Stage 4 prostate Cancer, Gleason 10, PSA 32 cancer mets located in right hip, lymph nodes, T11 spine, and 2 liver lesions. At the time of diagnosis my Dad was 60 years old and is now 64. When my Dad was initially diagnosed he was experiencing
ascott32
in
Advanced Prostate Cancer
8 years ago
Provenge Poster Child
2008 Gleason 4+3, 2008 RP, 2009 Radiation treatments, castrate resistant, ADT and Casodex, PSA 20 with metastasized lymph nodes, 2012 Provenge, present PSA 0.2 with metastasized lymph nodes, still doing Hormone Therapy
2008 Gleason 4+3, 2008 RP, 2009 Radiation treatments, castrate resistant, ADT and Casodex, PSA 20 with metastasized lymph nodes, 2012 Provenge, present PSA 0.2 with metastasized lymph nodes, still doing Hormone Therapy
Scoop65
in
Advanced Prostate Cancer
8 years ago
My Intro...
I was applying for life insurance and submitted a blood sample. So got a letter back saying that my PSA was at 42 so I better check that out. So after a visit with a urologist, I was diagnosed with PC with a call from my urologist on Friday December 31, 2008 at 5:30pm on New Year’s Eve! He could have
I was applying for life insurance and submitted a blood sample. So got a letter back saying that my PSA was at 42 so I better check that out. So after a visit with a urologist, I was diagnosed with PC with a call from my urologist on Friday December 31, 2008 at 5:30pm on New Year’s Eve! He could have
Don1157
in
Advanced Prostate Cancer
8 years ago
My journey so far
It has been 3 years since my diagnosis. Beginning PSA was 843 and Gleason was 4+5. Began with Lupron and Casodex. PSA declined to 78, but began rising again shortly. Tried degerilix briefly without success, then shifted to Zytiga for sever months. Progression slowed and PSA stabilized around 270. Moved
It has been 3 years since my diagnosis. Beginning PSA was 843 and Gleason was 4+5. Began with Lupron and Casodex. PSA declined to 78, but began rising again shortly. Tried degerilix briefly without success, then shifted to Zytiga for sever months. Progression slowed and PSA stabilized around 270. Moved
Gecrellin
in
Advanced Prostate Cancer
8 years ago
So here I am
In the last quarter of 2013 I began having erection and urination issues, which the urologist treated as BCH. Then in Feb. 2014 in my regular annual physical my PSA came in @ 5.0 and I had discussions with the urologist again and we decided to closely monitor, but took no tests. In July 2014 I began
In the last quarter of 2013 I began having erection and urination issues, which the urologist treated as BCH. Then in Feb. 2014 in my regular annual physical my PSA came in @ 5.0 and I had discussions with the urologist again and we decided to closely monitor, but took no tests. In July 2014 I began
ETodd3
in
Advanced Prostate Cancer
8 years ago
Intro
I was diagnosed at 56 in 2012. PSA 8.0 Initial biopsy showed positive cores with Glesason 3 + 4. Sent biopsy to Johns Hopkins which read it 4 +5. Went to MD Anderson. Evaluated treatment options and third read was 3 +4. CT showed one pelvic lymph node was slightly enlarged,but not enough to be considered
I was diagnosed at 56 in 2012. PSA 8.0 Initial biopsy showed positive cores with Glesason 3 + 4. Sent biopsy to Johns Hopkins which read it 4 +5. Went to MD Anderson. Evaluated treatment options and third read was 3 +4. CT showed one pelvic lymph node was slightly enlarged,but not enough to be considered
scarlino
in
Advanced Prostate Cancer
8 years ago
First 3 months on combined androgen blockade...
Hello - My name is Graham Colville. I'm a 71-year-old Canadian living in Cyprus and was diagnosed in March 2002 while living in London, England. In May 2002 I had radical prostatectomy at Sloan Kettering in NY. My Gleason grade was 4 + 3 = 7 and pathology showed spread to a seminal vesicle but otherwise
Hello - My name is Graham Colville. I'm a 71-year-old Canadian living in Cyprus and was diagnosed in March 2002 while living in London, England. In May 2002 I had radical prostatectomy at Sloan Kettering in NY. My Gleason grade was 4 + 3 = 7 and pathology showed spread to a seminal vesicle but otherwise
Arcticfox44
in
Advanced Prostate Cancer
8 years ago
Starting PSA was 5,006.4
In November 2013 I was in a Northern California emergency room with severe lower back pain at age 65. Turned out I had previously undiagnosed, widespread metastatic prostate cancer. PSA was 5,006.4, with testosterone level of 908, and Alkaline Phosphatase around 424. Nuclear medicine bone scan lighted
In November 2013 I was in a Northern California emergency room with severe lower back pain at age 65. Turned out I had previously undiagnosed, widespread metastatic prostate cancer. PSA was 5,006.4, with testosterone level of 908, and Alkaline Phosphatase around 424. Nuclear medicine bone scan lighted
ctarleton
in
Advanced Prostate Cancer
8 years ago
My Intro - Ned in St Louis
I was diagnosed at age 60, in Aug 2010, with 12 positive cores out of the 12 sampled in my biopsy! I had lost my mother to colon cancer when she was age 59, and my secret goal was to at least make it past that age. The urologist called me, very concerned with those results, the DAY AFTER my 60th birthday
I was diagnosed at age 60, in Aug 2010, with 12 positive cores out of the 12 sampled in my biopsy! I had lost my mother to colon cancer when she was age 59, and my secret goal was to at least make it past that age. The urologist called me, very concerned with those results, the DAY AFTER my 60th birthday
NCrocker
in
Advanced Prostate Cancer
8 years ago
My Introduction
Hi, my name is Jim Bell. I' 71 years old, 72 next month. I was diagnosed with prostate cancer seven years ago. My PSA was at 44 and my Gleason score was a 7. I had a radical prostectemy which left me impotent and incontinent. After about a year, my PSA started to rise and I had 39 radiation treatments
Hi, my name is Jim Bell. I' 71 years old, 72 next month. I was diagnosed with prostate cancer seven years ago. My PSA was at 44 and my Gleason score was a 7. I had a radical prostectemy which left me impotent and incontinent. After about a year, my PSA started to rise and I had 39 radiation treatments
jeb350
in
Advanced Prostate Cancer
8 years ago
Low PSA with a Gleason 8 diagnosis
I was diagnosed with prostatitis and BPH (Benign Prostate Hyperplasia) in 2001, but since my PSA level remained around 1.5 for the next seven years, my primary care physician always assumed it was simply an enlarged prostate she was feeling via the DRE (Digital Rectal Examination) at my annual physical
I was diagnosed with prostatitis and BPH (Benign Prostate Hyperplasia) in 2001, but since my PSA level remained around 1.5 for the next seven years, my primary care physician always assumed it was simply an enlarged prostate she was feeling via the DRE (Digital Rectal Examination) at my annual physical
craigpynn
in
Advanced Prostate Cancer
8 years ago
On to the Next Step
2012-Urologist biopsy with Gleason 9; (2012)-Dattoli Cancer Center, Sarasota, FL for Color Dopler affirmative PCA; 8 weeks Conformed Radiation, seeding, follow-up radiation; ADT. (2014) PSA doubling-Sand Lake Imaging Pet,CT/MRI, Ferheim (sp) imaging-no mets found. Continued ADT and supplements+Metformin
2012-Urologist biopsy with Gleason 9; (2012)-Dattoli Cancer Center, Sarasota, FL for Color Dopler affirmative PCA; 8 weeks Conformed Radiation, seeding, follow-up radiation; ADT. (2014) PSA doubling-Sand Lake Imaging Pet,CT/MRI, Ferheim (sp) imaging-no mets found. Continued ADT and supplements+Metformin
Baddawg
in
Advanced Prostate Cancer
8 years ago
Zytiga and Xtandi .... what do you think about this?
Diagnosed in ‘2008 at the age of 50. Because it was in his lymph node, he went with Casodex (30 days), Lupron (2 years) and radiation (40 external beam). In ‘2012 he did Taxotere when his PSA had a one month doubling rate. Planned to do 6 months, but was stopped at four months with heavy side effects
Diagnosed in ‘2008 at the age of 50. Because it was in his lymph node, he went with Casodex (30 days), Lupron (2 years) and radiation (40 external beam). In ‘2012 he did Taxotere when his PSA had a one month doubling rate. Planned to do 6 months, but was stopped at four months with heavy side effects
Darryl
Partner
in
Advanced Prostate Cancer
8 years ago
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