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Advancing Prostate Cancer Care: Treatment Approaches to Precision Medicine, Biomarker Innovations, and Equitable Access -ASCO - May 23, 2024
While not a lot of specific focus on PCa (Like at the GU ASCO Meeting earlier this year), this full-access section from their Educational Book released at this week's ASCO Annual Meeting in Chicago may be of interest to those here who want to understand the oncology community's current view on precision
While not a lot of specific focus on PCa (Like at the GU ASCO Meeting earlier this year), this full-access section from their Educational Book released at this week's ASCO Annual Meeting in Chicago may be of interest to those here who want to understand the oncology community's current view on precision
cujoe
in
Fight Prostate Cancer
3 months ago
Has T3 made me go overactive? Please help
Hi, I wonder if anyone can help me please. I got tests done to check my iron as I am going to have an iron infusion next week. They also checked my thyroid and the results are a bit high. (See pic) For context, i have Hashimotos and am Hypothyroid. I am on 175mcg daily of Levothyroxine and 5mcg daily
Hi, I wonder if anyone can help me please. I got tests done to check my iron as I am going to have an iron infusion next week. They also checked my thyroid and the results are a bit high. (See pic) For context, i have Hashimotos and am Hypothyroid. I am on 175mcg daily of Levothyroxine and 5mcg daily
sugarbee1981
in
Thyroid UK
3 months ago
Genetic background strongly influences the impact of carrying the Thr92Ala-DIO2 polymorphism in the male mouse
Are you male? Are you a mouse? Do you carry the Thr92Ala-DIO2 allele? Can you wait for the publication of this paper? Can you wait for the human version of this trial? And do you consider it necessary to wait for the eventual publication of the human trial before considering T3? It is undoubtedly
Are you male? Are you a mouse? Do you carry the Thr92Ala-DIO2 allele? Can you wait for the publication of this paper? Can you wait for the human version of this trial? And do you consider it necessary to wait for the eventual publication of the human trial before considering T3? It is undoubtedly
helvella
Thyroid UK
in
Thyroid UK
3 months ago
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If you take a small dose of T3 (6mcg) does this slowly build up in your system or will it get used quickly every day?
I’m taking 6.25mcg of T3 for a week now I just wondered if this will build up in your system similar to T4? I know T4 is the storage hormone so that builds up slowly. I didn’t know whether the 6mcg will build up aswell as I was thinking of adding a little more but I don’t want to add more if it’s still
I’m taking 6.25mcg of T3 for a week now I just wondered if this will build up in your system similar to T4? I know T4 is the storage hormone so that builds up slowly. I didn’t know whether the 6mcg will build up aswell as I was thinking of adding a little more but I don’t want to add more if it’s still
ockerdoc
in
Thyroid UK
3 months ago
half life T3 in NDT
I've read over a period of time that T3 has half-life of anywhere from 2-2.5 days. I have, always, assumed (bad thing!) that was for synthetic T3. Anyone know, if that time-frame is applicable to dessicated T3? My FT3 shot up from 2.7 in late Feb. to 3.85 2 weeks ago. I had increased dose from97.5
I've read over a period of time that T3 has half-life of anywhere from 2-2.5 days. I have, always, assumed (bad thing!) that was for synthetic T3. Anyone know, if that time-frame is applicable to dessicated T3? My FT3 shot up from 2.7 in late Feb. to 3.85 2 weeks ago. I had increased dose from97.5
terebol
in
Thyroid UK
3 months ago
Sudden crash back into fatigue.
After seeing my Endo last week, my T3 was kept the same (5mcg twice a day) and my t4 was put back up to 75. Usually it takes weeks before any difference shows doesn’t it? It wouldn’t be any difference in this case? The day after I started back on the higher dose I felt exhausted, insomnia and poor sleep
After seeing my Endo last week, my T3 was kept the same (5mcg twice a day) and my t4 was put back up to 75. Usually it takes weeks before any difference shows doesn’t it? It wouldn’t be any difference in this case? The day after I started back on the higher dose I felt exhausted, insomnia and poor sleep
Loopnova
in
Thyroid UK
3 months ago
reverse t3 testing.
I’m on a journey with t3 so far taking has not affected serum t3 levels and I have read that reverse t3 can block active t3. Has anyone here tested for this and did you find it useful? I understand it is a somewhat controversial test in the medical world Thanks!
I’m on a journey with t3 so far taking has not affected serum t3 levels and I have read that reverse t3 can block active t3. Has anyone here tested for this and did you find it useful? I understand it is a somewhat controversial test in the medical world Thanks!
Mag999
in
Thyroid UK
3 months ago
help needing t4
I wonder if anyone could help me I need to buy a top up of t4 without a prescription if someone could be as helpful as to give me an email address thankyou
I wonder if anyone could help me I need to buy a top up of t4 without a prescription if someone could be as helpful as to give me an email address thankyou
Kowbie
in
Thyroid UK
3 months ago
Up and down…
I’m on 87.5mcg levo. My last blood tests showed low ferritin (32), t4 19.1 (12-22) t3 3.9 (3.1-6.8), slightly over range testosterone (on hrt but not on any testosterone). I’m seeing a thyroid specialist for the first time at the end of the month and will ask about iron testing and low ferritin, and
I’m on 87.5mcg levo. My last blood tests showed low ferritin (32), t4 19.1 (12-22) t3 3.9 (3.1-6.8), slightly over range testosterone (on hrt but not on any testosterone). I’m seeing a thyroid specialist for the first time at the end of the month and will ask about iron testing and low ferritin, and
JoJoloveschocolate
in
Thyroid UK
6 days ago
low resting heart rate
Hi All, I have Low resting heart rate, regardless of upping dose. I’ve upped my T3 meds from 20mcg to 25mcg and I take 100mcg of Levo and my resting hr stays at 52/51bpm my resting heart rate was the same at 15mcg T3 too. Initially when I up the dose for 2-3 days resting heart rate will increase to
Hi All, I have Low resting heart rate, regardless of upping dose. I’ve upped my T3 meds from 20mcg to 25mcg and I take 100mcg of Levo and my resting hr stays at 52/51bpm my resting heart rate was the same at 15mcg T3 too. Initially when I up the dose for 2-3 days resting heart rate will increase to
Thyroid_mum
in
Thyroid UK
3 months ago
Can anyone comment on my daughter's blood tests and advise what - if anything - we should do next?
My daughter is 18. I first requested blood tests with the GP when she was 15. This was during covid. I had to fight over the phone for them but she'd put on weight rapidly, she especially looked to be retaining fluid in her legs, feet, hands and face. Other symptoms = tiredness, slow movements, dry eyes
My daughter is 18. I first requested blood tests with the GP when she was 15. This was during covid. I had to fight over the phone for them but she'd put on weight rapidly, she especially looked to be retaining fluid in her legs, feet, hands and face. Other symptoms = tiredness, slow movements, dry eyes
ReaCoe
in
Thyroid UK
3 months ago
Why does Levothyroxine cause weight gain if it treats hypothyroidism, weight gain being a hypo symptom?
Shouldn't it help rectify hypo symptoms not make them worse? This baffles me! I wish I could revert back to Levothyroxine and use it together with T3 as NDT is extortionately priced, and not working brilliantly for me anymore, however, weight gain is my biggest fear, and I read so much about this on
Shouldn't it help rectify hypo symptoms not make them worse? This baffles me! I wish I could revert back to Levothyroxine and use it together with T3 as NDT is extortionately priced, and not working brilliantly for me anymore, however, weight gain is my biggest fear, and I read so much about this on
MindfulMoments
in
Thyroid UK
3 months ago
Thyroid uptake scan results
hi folks, In February I was diagnosed as hyperthyroid. My T4 was high at 38 (ref range 11-22). TPOAb high at 178 (range 0-35). TRAb negative at 3 (ref 0-3.3). I was referred recently for a thyroid uptake scan to conclude Graves diagnosis. Findings: The thyroid gland is not enlarged however there
hi folks, In February I was diagnosed as hyperthyroid. My T4 was high at 38 (ref range 11-22). TPOAb high at 178 (range 0-35). TRAb negative at 3 (ref 0-3.3). I was referred recently for a thyroid uptake scan to conclude Graves diagnosis. Findings: The thyroid gland is not enlarged however there
Hungryallthetimes
in
Thyroid UK
3 months ago
T3 in Crete
Hi, I am going to Crete and would like to pick up some T3, has anyone been recently and is easy to buy? Thanks very much.
Hi, I am going to Crete and would like to pick up some T3, has anyone been recently and is easy to buy? Thanks very much.
Bollieforme
in
Thyroid UK
3 months ago
SC5NA Gene mutation
hey, I’ve just been diagnosed with an SC5NA gene mutation after having genetic testing done which has identified the cause of my Brugada, I’ve now been advised I’m at risk of cardiomyopathy. Has anyone else experienced this diagnosis and can offer any advice?
hey, I’ve just been diagnosed with an SC5NA gene mutation after having genetic testing done which has identified the cause of my Brugada, I’ve now been advised I’m at risk of cardiomyopathy. Has anyone else experienced this diagnosis and can offer any advice?
Lilbandit88
in
British Heart Foundation
3 months ago
Follow up
I had a follow up appt with my Dr yesterday. Told her I am down from 10 mg ropinorole to 3 mg with the help of 25 mg tramadol when needed. She thought that was great but does not want me to use tramadol. She said it causes Rls. She gave me gabapentin 300 mg. to try instead of Tramadol. I asked about
I had a follow up appt with my Dr yesterday. Told her I am down from 10 mg ropinorole to 3 mg with the help of 25 mg tramadol when needed. She thought that was great but does not want me to use tramadol. She said it causes Rls. She gave me gabapentin 300 mg. to try instead of Tramadol. I asked about
ParisianTN55
in
Restless Legs Syndrome
3 months ago
Experiences of NDT v Levo and Lio
Hello again, I have been trialling NDT (2 grains since mid March 2024. I was previously on 75mcg Levo and 10mcg Lio (from NHS Endo) but still had symptoms. Both T4 and T3 levels are better on NDT yet I’m not feeling improvement. The private GP I saw increased my dose to 2.25 grains and I felt jittery
Hello again, I have been trialling NDT (2 grains since mid March 2024. I was previously on 75mcg Levo and 10mcg Lio (from NHS Endo) but still had symptoms. Both T4 and T3 levels are better on NDT yet I’m not feeling improvement. The private GP I saw increased my dose to 2.25 grains and I felt jittery
Piglet1956
in
Thyroid UK
3 months ago
Free T3 not increasing with T4 increase
Hi, in May I had been prescribed 20mg of T3 (and not advised to start low) so after 2 weeks I was naturally feeling horrendous with such a high starting dose and my T4 was still very low (52% through range). Thus on advice from the amazing guys on this forum, I stopped the T3 altogether and have been
Hi, in May I had been prescribed 20mg of T3 (and not advised to start low) so after 2 weeks I was naturally feeling horrendous with such a high starting dose and my T4 was still very low (52% through range). Thus on advice from the amazing guys on this forum, I stopped the T3 altogether and have been
Hippocamp
in
Thyroid UK
20 days ago
2022 'T3 only' crossover study (compared to Levo only) shows good results .
just sticking this on a post so i can find it easily [i]Front. Endocrinol., 22 February 2022[/i] [i]Sec. Thyroid Endocrinology[/i] [i]Volume 13 - 2022 | https://doi.org/10.3389/fendo.2022.816566[/i] [i]
Effect of Liothyronine Treatment on Quality of Life in Female Hypothyroid Patients With Residual
just sticking this on a post so i can find it easily [i]Front. Endocrinol., 22 February 2022[/i] [i]Sec. Thyroid Endocrinology[/i] [i]Volume 13 - 2022 | https://doi.org/10.3389/fendo.2022.816566[/i] [i]
Effect of Liothyronine Treatment on Quality of Life in Female Hypothyroid Patients With Residual
tattybogle
in
Thyroid UK
4 months ago
thydroid T4
hello everyone hope your keeping as well as you can, I’m just wanting to ask if anyone can put me in touch with a supplier for t4 I’m taking accord thyroxine and need to buy some privately no prescription thankyou looking forward to your replies
hello everyone hope your keeping as well as you can, I’m just wanting to ask if anyone can put me in touch with a supplier for t4 I’m taking accord thyroxine and need to buy some privately no prescription thankyou looking forward to your replies
Kowbie
in
Thyroid UK
4 months ago
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