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Empagliflozin / Metformin
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Effects of Metformin and Statins on MCRPC
This trial appears to support the use of Metformin and Statin for men with MCRPC. http://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/137274-effects-of-metformin-and-statins-on-outcomes-in-men-with-castration-resistant-metastatic-prostate-cancer-secondary-analysis-of-cou-aa-301
This trial appears to support the use of Metformin and Statin for men with MCRPC. http://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/137274-effects-of-metformin-and-statins-on-outcomes-in-men-with-castration-resistant-metastatic-prostate-cancer-secondary-analysis-of-cou-aa-301
EdBar
in
Advanced Prostate Cancer
2 years ago
Efficacy of Once- Weekly semaglutide V/s Thrice Daily Insulin Aspart as Add-on to Metformin and Insulin Glargine in Type 2 Diabetes..
Type 2 diabetes is a progressive disease, requiring treatment intensification. May have a look at the recent article published in [i]
Diabetes
[/i] journal. TAKE-HOME MESSAGE… * In the SUSTAIN 11 trial, the investigators compared weekly semaglutide to meal-time insulin aspart in patients with type
Type 2 diabetes is a progressive disease, requiring treatment intensification. May have a look at the recent article published in [i]
Diabetes
[/i] journal. TAKE-HOME MESSAGE… * In the SUSTAIN 11 trial, the investigators compared weekly semaglutide to meal-time insulin aspart in patients with type
DRH-sangli
Star
in
Diabetes India
2 years ago
Be careful about the studies you see posted on this site
The wonderful thing about this site is we are free to post anything we want within the bounds of civility. But that is also a danger - many people post studies without regard to truth. Truth is judged by the scientific process. Two studies this week illustrate why patients should never use retrospective
The wonderful thing about this site is we are free to post anything we want within the bounds of civility. But that is also a danger - many people post studies without regard to truth. Truth is judged by the scientific process. Two studies this week illustrate why patients should never use retrospective
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
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More evidence that metformin probably has no effect in prostate cancer
This was among 3,649 women with breast cancer. https://jamanetwork.com/journals/jama/fullarticle/2792615 But taken together with all the randomized clinical trials so far among men with prostate cancer, it does increase our skepticism. Here are the RCTs so far for prostate cancer: https://www.prostatecancer.news
This was among 3,649 women with breast cancer. https://jamanetwork.com/journals/jama/fullarticle/2792615 But taken together with all the randomized clinical trials so far among men with prostate cancer, it does increase our skepticism. Here are the RCTs so far for prostate cancer: https://www.prostatecancer.news
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
What should I ask GP at follow up appointment after blood test ?
Hi, I’m 28 and presumed to have PCOS. Blood tests will confirm. My weight and other symptoms have rocketed in the last few years. I’ve gone from a 26in waist to a 32in. My body shape has totally morphed and it’s the lowest I’ve ever felt about myself. I have been very cautious and aware of my diet etc
Hi, I’m 28 and presumed to have PCOS. Blood tests will confirm. My weight and other symptoms have rocketed in the last few years. I’ve gone from a 26in waist to a 32in. My body shape has totally morphed and it’s the lowest I’ve ever felt about myself. I have been very cautious and aware of my diet etc
BlenheimBlue
in
PCOS UK (Verity)
2 years ago
scared to take my first tablet
Hi everyone I start metformin today I'm suppose to take my first tablet with lunch but iv built myself up so much about it I'm scared to take them because of the side affects are they that bad :(
Hi everyone I start metformin today I'm suppose to take my first tablet with lunch but iv built myself up so much about it I'm scared to take them because of the side affects are they that bad :(
Parris96
in
PCOS UK (Verity)
2 years ago
Menopause
Has anyone had the experience of raised BP and sugar levels as a result of being in the menopause? I am on Metformin and Jardiance and I eat carefully such as low carbs and sugar. I do have a sweet tooth so have to curb this which is of course tricky. I exercise regularly but my blood count still remains
Has anyone had the experience of raised BP and sugar levels as a result of being in the menopause? I am on Metformin and Jardiance and I eat carefully such as low carbs and sugar. I do have a sweet tooth so have to curb this which is of course tricky. I exercise regularly but my blood count still remains
Lyndsayd
in
High Blood Pressure Support
2 years ago
Effects of metformin and statins on outcomes in men with castration-resistant metastatic prostate cancer
New international study, below [1]. "Secondary analysis of COU-AA-301 and COU-AA-302" [2] & [3].
Objective:
To determine whether metformin or statins ± abiraterone acetate plus prednisone/prednisolone (AAP) influence OS {overall survival} and PSA-RR {prostate specific antigen response rate}.
New international study, below [1]. "Secondary analysis of COU-AA-301 and COU-AA-302" [2] & [3].
Objective:
To determine whether metformin or statins ± abiraterone acetate plus prednisone/prednisolone (AAP) influence OS {overall survival} and PSA-RR {prostate specific antigen response rate}.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Rank Neutraceuticals / Off-Label Drugs By Most Likely Most Beneficial
I'm curious about the opinions of members here on how they would currently rank Neutraceutical and off-label use drugs in order of highest benefit potential (most confirming clinical trial evidence combined with actual therapeutic or synergistic therapeutic effect) in slowing/stopping PCa progression
I'm curious about the opinions of members here on how they would currently rank Neutraceutical and off-label use drugs in order of highest benefit potential (most confirming clinical trial evidence combined with actual therapeutic or synergistic therapeutic effect) in slowing/stopping PCa progression
jazj
in
Advanced Prostate Cancer
2 years ago
Current Consensus on Metformin and Berberine?
I've been studying Metformin (not Berberine, yet). My conclusion reading all the latest studies, especially the large meta-studies, is that evidence is weak on Metformin having a significant positive effect BY ITSELF. There appears to be significant evidence it has a positive effect when used synergistically
I've been studying Metformin (not Berberine, yet). My conclusion reading all the latest studies, especially the large meta-studies, is that evidence is weak on Metformin having a significant positive effect BY ITSELF. There appears to be significant evidence it has a positive effect when used synergistically
jazj
in
Advanced Prostate Cancer
2 years ago
Having a bit of a trying time.
Hello - the last few days have been not so good - no energy or motivation and this morning I had my breakfast and felt so sick afterwards I had to go back to bed. It has been slowly going downhill for a few days now.My biggest worry is that this all points to kidney function and the dialysis question
Hello - the last few days have been not so good - no energy or motivation and this morning I had my breakfast and felt so sick afterwards I had to go back to bed. It has been slowly going downhill for a few days now.My biggest worry is that this all points to kidney function and the dialysis question
fartikins
in
Kidney Disease
2 years ago
dapagliflozin
Hi Is anyone taking dapagliflozin for their Heart condition,just wondering as I’ve just been prescribed them curious about side effects etc that may have been encountered? Thanks,Ali
Hi Is anyone taking dapagliflozin for their Heart condition,just wondering as I’ve just been prescribed them curious about side effects etc that may have been encountered? Thanks,Ali
AliDerees
in
British Heart Foundation
2 years ago
HF r EF HF p EF
Hello Sorry for using abbreviations, but thought they may catch the attention of someone who knows the answer !!! Question is how do you tell if you are classified as reduced or preserved my EF is currently 39 % which has reduced from 44 % which I have maintained for around 6 years. I believe this
Hello Sorry for using abbreviations, but thought they may catch the attention of someone who knows the answer !!! Question is how do you tell if you are classified as reduced or preserved my EF is currently 39 % which has reduced from 44 % which I have maintained for around 6 years. I believe this
Prada47
in
British Heart Foundation
2 years ago
Difficulties in getting aa good night's sleep
My husband (82) has very recently developed heart problems which are being investigated further. He's on a cocktail of medication including beta blocker, endoxaban, diuretics and dapagliflozin. Big problem is he can get to sleep quite easily but then wakes up with a start after 5 - 10 minutes. He's
My husband (82) has very recently developed heart problems which are being investigated further. He's on a cocktail of medication including beta blocker, endoxaban, diuretics and dapagliflozin. Big problem is he can get to sleep quite easily but then wakes up with a start after 5 - 10 minutes. He's
constantheart
in
British Heart Foundation
2 years ago
Just Diagnosed type 2, feeling a bit downhearted!
Having been told 3 years ago that I was pre diabetic I made as many changes to my diet and lifestyle (other health conditions and covid permitting) to try and avoid progressing to the "I am diabetic" status but today I have been told I am diabetic, steroid induced. My doctor prescribed gliclazide in
Having been told 3 years ago that I was pre diabetic I made as many changes to my diet and lifestyle (other health conditions and covid permitting) to try and avoid progressing to the "I am diabetic" status but today I have been told I am diabetic, steroid induced. My doctor prescribed gliclazide in
AF59
in
Diabetes Research & Wellness Foundation
2 years ago
Salmon Protein Hydrolysate
New study below [1]. Anyone here using
Salmon Protein Hydrolysate
? FWIW: "A growing body of evidence implicates iron dysmetabolism in prostate cancer progression. A bioactive peptide-rich salmon protein hydrolysate (SPH) has previously been demonstrated to modulate iron homeostatic mechanisms.
New study below [1]. Anyone here using
Salmon Protein Hydrolysate
? FWIW: "A growing body of evidence implicates iron dysmetabolism in prostate cancer progression. A bioactive peptide-rich salmon protein hydrolysate (SPH) has previously been demonstrated to modulate iron homeostatic mechanisms.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Whether to push for a diagnosis
Hello All, my first post and I'm afraid it will be a long one but perhaps someone has had similar experiences and can help. I am male and 53 years old. I’ve had a diagnosis of Raynaud’s since my teens. Over the last ten years or so I developed visible red veins on the backs of my hands, forearms, feet
Hello All, my first post and I'm afraid it will be a long one but perhaps someone has had similar experiences and can help. I am male and 53 years old. I’ve had a diagnosis of Raynaud’s since my teens. Over the last ten years or so I developed visible red veins on the backs of my hands, forearms, feet
2reddogs
in
Scleroderma & Raynaud's UK (SRUK)
2 years ago
Inhibition of Stearoyl-CoA Desaturase by Sterculic Oil Reduces Proliferation and Induces Apoptosis in Prostate Cancer Cells
Prostate cancer (PCa) is a common type of cancer affecting male population. PCa treatments have side effects and are temporarily effective, so new therapeutic options are being investigated. Due to the high demand of energy for cell proliferation, an increase in the expression and activity of lipogenic
Prostate cancer (PCa) is a common type of cancer affecting male population. PCa treatments have side effects and are temporarily effective, so new therapeutic options are being investigated. Due to the high demand of energy for cell proliferation, an increase in the expression and activity of lipogenic
Hidden
in
Advanced Prostate Cancer
2 years ago
Natural metformin alternatives
I know that some of you take metformin. I read that it comes from a natural ingredient called French lilac, also known as Goat's Rue. It is in other plants as well. Has anyone taken any of those natural forms instead of metformin? Thanks.
I know that some of you take metformin. I read that it comes from a natural ingredient called French lilac, also known as Goat's Rue. It is in other plants as well. Has anyone taken any of those natural forms instead of metformin? Thanks.
dhccpa
in
Advanced Prostate Cancer
2 years ago
Really lost.
so so fed up and in tears. The self injecting of B12 is going well, not arranged re checking of bloods yet going to ask in a few months. So I am fat, have carried extra fat for a few years, but seems to have got out of hand last couple. Early last year had all sorts of blood done after insisting
so so fed up and in tears. The self injecting of B12 is going well, not arranged re checking of bloods yet going to ask in a few months. So I am fat, have carried extra fat for a few years, but seems to have got out of hand last couple. Early last year had all sorts of blood done after insisting
Polo22
in
Pernicious Anaemia Society
2 years ago
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