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Dopamine
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Is RLS / PLMS really the cause of all my problems ?
I thought that only happened with
dopamine
agonists and not on opiates / opioids ? Most of what I have read on forums etc suggest the overwhelming symptoms of RLS / PLMS are pain / uncomfortable sensations and this is what has a serious impact on quality of life.
I thought that only happened with
dopamine
agonists and not on opiates / opioids ? Most of what I have read on forums etc suggest the overwhelming symptoms of RLS / PLMS are pain / uncomfortable sensations and this is what has a serious impact on quality of life.
DesperateDann
in
Restless Legs Syndrome
6 years ago
My subtype : Postprandial and orthostatic hypotension in Parkinson's disease. 1987
A significant relationship was found in the PD group between the degree of postprandial hypotension and the 24-hour mean value of
dopamine
excretion. Eight PD subjects also showed orthostatic hypotension during the tilt test (performed in the morning hours) and in the postprandial phase.
A significant relationship was found in the PD group between the degree of postprandial hypotension and the 24-hour mean value of
dopamine
excretion. Eight PD subjects also showed orthostatic hypotension during the tilt test (performed in the morning hours) and in the postprandial phase.
aspergerian13
in
Cure Parkinson's
6 years ago
Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs
Existing therapeutic strategies for managing Parkinson disease (PD), which focus on addressing the loss of
dopamine
and dopaminergic function linked with degeneration of dopaminergic neurons, are limited by side effects and lack of long-term efficacy.
Existing therapeutic strategies for managing Parkinson disease (PD), which focus on addressing the loss of
dopamine
and dopaminergic function linked with degeneration of dopaminergic neurons, are limited by side effects and lack of long-term efficacy.
Farooqji
in
Cure Parkinson's
6 years ago
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Have someone had an experience with a supplement that works as a MAO inhibitor in PD?
Although bupropion is a med for depression it works to me in my walking coordination because it capabilities to increase
dopamine
. I quit after 5 years in a row on that med as started to having small seizures just noted by people surrounding me.
Although bupropion is a med for depression it works to me in my walking coordination because it capabilities to increase
dopamine
. I quit after 5 years in a row on that med as started to having small seizures just noted by people surrounding me.
marnegro
in
Cure Parkinson's
6 years ago
How I tried to keep my Dopamine agonist dose under control for >10 years
I just now read a comment by involuntary dancer who wondered if reducing dose when effectiveness goes down might help to get a longer effective period out of
dopamine
agonist treatments.
I just now read a comment by involuntary dancer who wondered if reducing dose when effectiveness goes down might help to get a longer effective period out of
dopamine
agonist treatments.
Wonko_TheSane
in
Restless Legs Syndrome
6 years ago
N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data
LINK: http://www.faim.org/n-acetyl-cysteine-may-support-
dopamine
-neurons-in-parkinsons-disease-preliminary-clinical-and-cell
LINK: http://www.faim.org/n-acetyl-cysteine-may-support-
dopamine
-neurons-in-parkinsons-disease-preliminary-clinical-and-cell
hripka
in
Cure Parkinson's
6 years ago
Introduction!
I have been to my GP and had a blood test, all of which showed normal results so i was started on a course of
Dopamine
which did nothing for me and also Ropinirole. During the summer months, i have noticed a major decrease in the urges and sensations.
I have been to my GP and had a blood test, all of which showed normal results so i was started on a course of
Dopamine
which did nothing for me and also Ropinirole. During the summer months, i have noticed a major decrease in the urges and sensations.
mel_hancock
in
Restless Legs Syndrome
6 years ago
What Brain Chemicals/Neurotransmitters Do People With ADHD Lack, And What Problems Does That Bring?
Dopamine
: A neurotransmitter in the brain that affects your levels of concentration, motivation, pleasure senses, and sense of pain.
Dopamine
: A neurotransmitter in the brain that affects your levels of concentration, motivation, pleasure senses, and sense of pain.
Eclecticentric77
in
CHADD's ADHD Parents Together
6 years ago
What Brain Chemicals/Neurotransmitters Do People With ADHD Lack, And What Problems Does That Bring?
Dopamine
: A neurotransmitter in the brain that affects your levels of concentration, motivation, pleasure senses, and sense of pain.
Dopamine
: A neurotransmitter in the brain that affects your levels of concentration, motivation, pleasure senses, and sense of pain.
Eclecticentric77
in
CHADD's Adult ADHD Support
6 years ago
Low-Dose Aspirin Upregulates Tyrosine Hydroxylase and Increases Dopamine Production in Dopaminergic Neurons:
https://www.google.com.pk/amp/s/scienceofparkinsons.com/2018/09/12/aspirin/amp/
https://www.google.com.pk/amp/s/scienceofparkinsons.com/2018/09/12/aspirin/amp/
Farooqji
in
Cure Parkinson's
6 years ago
Has anyone successfully weaned off DA meds and feeling ok
So my question is, has anyone weaned off of DA's and went back to their pre
dopamine
antagonist life and found it more tolerable than dealing with augmentation, anxiety, restless body etc.
So my question is, has anyone weaned off of DA's and went back to their pre
dopamine
antagonist life and found it more tolerable than dealing with augmentation, anxiety, restless body etc.
mmb8083
in
Restless Legs Syndrome
6 years ago
Sources of dopamine
My original neuro said there was a choice between natural and synthetic
dopamine
. The former would give more immediate results where the latter was better over the long term. I've never asked what I'm actually getting. Is it porcine brains. 🐷
My original neuro said there was a choice between natural and synthetic
dopamine
. The former would give more immediate results where the latter was better over the long term. I've never asked what I'm actually getting. Is it porcine brains. 🐷
Johnmo
in
Cure Parkinson's
6 years ago
Dyskinesia from coffee?
I believe that coffee induce the
dopamine
I feel I have to reduce Comtan and sinemet, but how I do not know. Has anybody have any experience increase dyskinesia from coffee?? Thank you very much!!
I believe that coffee induce the
dopamine
I feel I have to reduce Comtan and sinemet, but how I do not know. Has anybody have any experience increase dyskinesia from coffee?? Thank you very much!!
luba1
in
Cure Parkinson's
6 years ago
Anyone tried elderflower tea?
There are a few articles about elderflower that show promise. https://www.realnatural.org/native-american-herbs-parkinsons-disease/ Extract "The finding of four herbal medicines that induce Nrf2 among
dopamine
-producing brain cells is important.
There are a few articles about elderflower that show promise. https://www.realnatural.org/native-american-herbs-parkinsons-disease/ Extract "The finding of four herbal medicines that induce Nrf2 among
dopamine
-producing brain cells is important.
gingerj
in
Cure Parkinson's
6 years ago
All you need to know about the Mitochondria , the cell Powerhouse
All these may directly or indirectly affect the mitochondrial function of protein degradation systems, including UPS and ALP, and thereby, cause the death of
dopamine
neurons.”
All these may directly or indirectly affect the mitochondrial function of protein degradation systems, including UPS and ALP, and thereby, cause the death of
dopamine
neurons.”
Kia17
in
Cure Parkinson's
6 years ago
Re : Dopamine agonists .. help .. plz ! 😱
Has anyone had similar .. or bad reaction … but switched to
Dopamine
agonist of NONE - ERGOLINE class ie .. Pramipexole (Mirapex, Mirapexin, Sifrol) and then had good result ??
Has anyone had similar .. or bad reaction … but switched to
Dopamine
agonist of NONE - ERGOLINE class ie .. Pramipexole (Mirapex, Mirapexin, Sifrol) and then had good result ??
Svengolly
in
Restless Legs Syndrome
6 years ago
AGM 1st September
Let’s see if we can raise the issue of a letter to BMA and Association of Neurologists about the increase in reported cases of Augmentation on
dopamine
agonists and best advice on withdrawal. Jools
Let’s see if we can raise the issue of a letter to BMA and Association of Neurologists about the increase in reported cases of Augmentation on
dopamine
agonists and best advice on withdrawal. Jools
Joolsg
in
Restless Legs Syndrome
6 years ago
How were your experiences coming off DAs?
I've noticed several things though, and therefore would like to know what others have experienced getting rid of their
dopamine
agonists. 1) my tremor has become worse - could that be a side effect of DA withdrawal?
I've noticed several things though, and therefore would like to know what others have experienced getting rid of their
dopamine
agonists. 1) my tremor has become worse - could that be a side effect of DA withdrawal?
Wonko_TheSane
in
Restless Legs Syndrome
6 years ago
My Journey With RLS, Experience With Kratom
I've run the gamut of medications and treatments. ..
dopamine
agonists (made it worse), gabapentin (worked for years but just stopped working at even the highest of doses), tramadol (same experience as gabapentin, years of efficacy then just stopped working), CBD oil, every vitamin, mineral, and herbal
I've run the gamut of medications and treatments. ..
dopamine
agonists (made it worse), gabapentin (worked for years but just stopped working at even the highest of doses), tramadol (same experience as gabapentin, years of efficacy then just stopped working), CBD oil, every vitamin, mineral, and herbal
BHogan
in
Restless Legs Syndrome
6 years ago
Doctor Buchfuhrer's Augmentation Algorithm
As augmentation due to
dopamine
agonists is such a strong (and unhappy) topic on this site, due chiefly to pramipexole, and as it has afflicted so many of us, I thought to post a very concise diagram from Doctor Buchfuhrer to help those needing to find a new direction, and who must help their doctors
As augmentation due to
dopamine
agonists is such a strong (and unhappy) topic on this site, due chiefly to pramipexole, and as it has afflicted so many of us, I thought to post a very concise diagram from Doctor Buchfuhrer to help those needing to find a new direction, and who must help their doctors
Parminter
in
Restless Legs Syndrome
6 years ago
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