Hi all, I've had RLS since about 10 years. I've taken Pramipexole for it nightly for about 6 years of those. I was up to 0.54mg per night, having to increase my dosage regularly to keep its effect on my sleep. When this didn't help anymore, being the maximum recommended for RLS, at least by some sources, I decided I need to try and at least take a break. I had tried Pregabalin before, but it only allowed me to reduce the Pramipexole by about 30 percent. On top of the RLS I recently developed a tremor in my left hand and am which is annoying sometimes, and disabling (typing at work) when it's bad. I have no idea if this is idiopathic, a side effect of taking rather high doses of a dopamine agonist for years, or even beginning Parkinson. My doc suggested cutting the DAs out cold and substituting with oxycodone, since that's required for properly testing for Parkinson.
Instead of that, I followed the advice given by knowledgeable people here: I started weaning myself off of the Pramipexole slowly and ordered Kratom, which luckily isn't regulated where I live (yet?). The Kratom had been great so far, having allowed me to cut my ppx dose in half over a week. I've noticed several things though, and therefore would like to know what others have experienced getting rid of their dopamine agonists.
1) my tremor has become worse - could that be a side effect of DA withdrawal?
2) My back muscles, which were always tense in sync with my RLS when it got worse, got so tense that I was in enough pain to worry about a herniated disc. I took some diclofenac (called Voltaren here) and it helped.
3) I wonder about a longer term solution. I'm considering Kratom only, or maybe rotating Kratom / Pramipexole to keep tolerance under control. I'll have to try and convince my doc, and I worry about Kratom being outlawed. What have you tried?
I'm starting a new job next week and would like to be prepared - what else have you experienced that I could be (at least mentally) prepared for?
Thanks in advance for your input,