Experiences with

Decitabine

Using a low dose of the epigenetic therapy drug decitabine, which is currently used to treat some blood cancers, the researchers significantly suppressed the growth of endocrine resistant breast tumours in mice and increased survival time by 90%.

Hello I am posting in the hope that it might help some of you…. I live in the UK and was diagnosed with HGSOC grade 4 in Jan 22. I have never been NED. I received first line chemo + Avastin, interval, suboptimal surgery then commenced Olaparib. Avastin continued for the permitted time and Olaparib

Hello this is a bit of a long post, so thank you for reading it. On the 13th March 2018 I was diagnosed with Ovarian cancer. I later found out that it was High Grade 3C. I was put on Carboplatin and Pacataxol and had my De Bulking operation on the 22nd July 2018 I was then NED for 2 years but as

Hi fellow warriors I haven't posted for a while but am on here daily getting my fix of courage & love. I'm currently being treated for my third recurrence. I've been on Carbo/Gem + Avastin since March. A few delays to treatment due to flu, covid, low neutrophils & low platelets. Just recently I had

Good evening ladies. My wife was diagnosed with OC in 2020 She's currently undergoing chemotherapy Carboplatin and Gemcitabine for a reoccurrence that has progressed to her supraclavicular lymph nodes and at the porta hepatis . She's unfortunately experiencing swelling, increasing pain/discomfort

hi all you very supportive ladies . 4 years since my diagnosis with stage 3 ovarian cancer I have had all the chemo combinations available plus Avastin and PARP inhibitors . I was then in a clinical trial for a year which had a small effect and finished in March. a couple of weeks ago , I was admitted

Due to start Gemcitabine in June for 2nd recurrence since surgery. Finished 7 months of caylex/ carbo in November. Really enjoying past 5 months of no treatment ( first time with no treatment in 3yrs). Not feeling ready to start again! Anyone else going through gemcitabine on its own and what your symptoms

hi peeps , I started new rounds of chemo for floating cluster cells , detected after they drained 2.5 L of fluid from my belly. CA 125 820 I’m on Carboplatin / gemcitabine Did anyone had the same?

Hi ladies, I've seen my oncologist today (well, one of his minions anyway) to find out about my treatment plan for my first recurrence. They've told me that I'll have gemcitabine with carboplatin this time round, so I was just wondering if anyone had any advice about this regime please? Even though carbotaxol

hi . Has anyone had Gemiciabine? I’ve been using a cold cap — but do you get hair loss with gemcitabine ? x x ❤️

The findings also indicated that an FDA-approved drug that inhibits epigenetic changes, called decitabine, could hold promise as a treatment for NEPC.

hi , has anyone had the combination of Carboplatin and gemcitabine . This may be my next course of treatment with Carboplatin plus gemcitabine one week, then gemcitabine only the second week with the 3rd week off. Gemcitabine seems to have some nasty side effects!!! I’d appreciate any comments .

Hi ladies! Could do with a bit of advice, as am spiralling a bit. For context, my Mum (54) was diagnosed with HGS stage 3c/4a OC in Jan 2022. BRACA gene negative. Immediately started three rounds of chemo, then had optimal debunking surgery and full hysterectomy, and continued with three more rounds

Morning everyone I was diagnosed with high grade serous ovarian cancer in 2020. I have gone through all the various chemo treatments available (pacitaxol, carboplatin, Caelyx, Gemcitabine, Niraparib and a trial. I was hoping to go on another trial but due to plural effusion, collapsed lung etc unfortunately

Hi everyone! For my mom's second recurrence, the doctor suggested Gemcitabine and Avastin without Carbo, as she got kidney issues and potential liver mets with the last regimen with Carbo+Caelyx. Has anyone used Gem and Avastin without Carbo? Was it effective? Did you have any side effects? Thank

I’m on my second recurrence and currently on carbo/gemcitabine.. ive had a reaction on last three cycles each one being harder than the last.. my question is has this happened to anyone else and , if so what was was the outcome? It’s been mentioned they may slow carb infusion over Two hour period

looks like the cancer is back! Im having a fluid drain in 15 sept and my cancer nurse is trying to bring my sppointment with oncologist firward.. gemcetabine has been mentioned. Anyone has existence of this drug, what sue effects if any did u experience.. this will be second recurrence .

I was reading an article about the tumor biome, and how bacteria & fungi may have a role in treatment resistance. I thought it might be interesting to review the work of Ravid Straussman at the Weizmann Institute of Science, Israel [1]. [2] (2017): Growing evidence suggests that microbes can

Hi, I posted 2 days ago that I was experiencing swollen legs and feet and was unsure if it was due to GSF injections. Had bloods done today prior to seeing oncologist. He felt the swelling was due to Gemcitabine. Apparently it is a common side effect!Only trouble now is my platelets are only 35, so

It looks like there’s no more options for me as I’ve been in hospital for a week with a bowel obstruction. HGSOC 3C. Had 2 lines chemo close together. Just had Carbo/gemcitabine but it made me so ill. Now I’m just waiting to see what happens. No food or drink. Any hints you brave ladies?