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We could tell in advance if enzalutamide works on a patient: computational biology
hopefully it will be clinically tested soon ”For the study in Nature Communications, Mitrofanova's team developed computational algorithms to discover why the prostate cancer drug enzalutamide (sold under the brand name Xtandi) never works for some patients and why it eventually stops working in others
hopefully it will be clinically tested soon ”For the study in Nature Communications, Mitrofanova's team developed computational algorithms to discover why the prostate cancer drug enzalutamide (sold under the brand name Xtandi) never works for some patients and why it eventually stops working in others
Maxone73
in
Advanced Prostate Cancer
6 months ago
Low Testosterone and value of continuing Hormone Therapy
83 year old male with a question: My understanding is that the role of hormone therapy is to lower one’s testosterone level. Does hormone therapy provide additional benefits in fighting prostate cancer beyond lowering testosterone levels? I was diagnosed with high grade prostate cancer (Gleason 10
83 year old male with a question: My understanding is that the role of hormone therapy is to lower one’s testosterone level. Does hormone therapy provide additional benefits in fighting prostate cancer beyond lowering testosterone levels? I was diagnosed with high grade prostate cancer (Gleason 10
saniku
in
Advanced Prostate Cancer
6 months ago
need some guidance, feeling desperate..
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
Kiki27
in
Advanced Prostate Cancer
6 months ago
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levothyroxine
Diagnosed eight weeks ago underactive thyroid even though I had no symptoms. 25mg given and 12 days later reduced to 12.5 as I was so ill. 4 weeks later I was bedridden, severe headaches and unable to urinate so took myself off them as Surgery would not respond. Informed Surgery what I had done they
Diagnosed eight weeks ago underactive thyroid even though I had no symptoms. 25mg given and 12 days later reduced to 12.5 as I was so ill. 4 weeks later I was bedridden, severe headaches and unable to urinate so took myself off them as Surgery would not respond. Informed Surgery what I had done they
Sunny-time
in
Thyroid UK
3 months ago
Antibody blood test
Hello I hope everyone is well. I was diagnosed with hashimotos about 9 weeks ago and have been on levothyroxine 50mg, blood test due at 12 weeks. Have also been taking vit d and ferroglobin. I have awful upper back, neck and foot pain. Currently under physio. Doctor did blood tests for rheumatoid arthritis
Hello I hope everyone is well. I was diagnosed with hashimotos about 9 weeks ago and have been on levothyroxine 50mg, blood test due at 12 weeks. Have also been taking vit d and ferroglobin. I have awful upper back, neck and foot pain. Currently under physio. Doctor did blood tests for rheumatoid arthritis
Nattycake
in
Thyroid UK
3 months ago
Creatine
I am on Ursofalk and very well fortunately. I take Bezafibrate for itch (life saver). I have embark on a fitness journey of Crossfit and after 12 months wish to improve even more. I am advised by my coach to take Creatine and that this is natural and improves performance and muscle recovery. Anyone
I am on Ursofalk and very well fortunately. I take Bezafibrate for itch (life saver). I have embark on a fitness journey of Crossfit and after 12 months wish to improve even more. I am advised by my coach to take Creatine and that this is natural and improves performance and muscle recovery. Anyone
amt50
in
PBC Foundation
6 months ago
Getting on with life.
My prostate has been removed, my psa is rising. I am not on medication. Basically, just getting on with life. Refusing to let this nonsense get me down. Thoughts anyone ?
My prostate has been removed, my psa is rising. I am not on medication. Basically, just getting on with life. Refusing to let this nonsense get me down. Thoughts anyone ?
Scouse0151
in
Advanced Prostate Cancer
6 months ago
CD20 Therapies (Ocrevus, Kesimpta, etc.) and potentially serious dental problems
This was an interesting post on the MS-blog. You have to get past the Dustin Hoffman in Marathon Man reference (which was a memorable scene!) to get down to the nitty gritty of why dental hygiene and regular checkups are so critical when when you're on certain MS therapies. https://multiple-sclerosis-research.org
This was an interesting post on the MS-blog. You have to get past the Dustin Hoffman in Marathon Man reference (which was a memorable scene!) to get down to the nitty gritty of why dental hygiene and regular checkups are so critical when when you're on certain MS therapies. https://multiple-sclerosis-research.org
CatsandCars
in
My MSAA Community
3 months ago
Selegeline/RBD?
It's often said that all of the treatments currently in use for Parkinson's offer symptomatic relief only, and do not affect underlying pathology. However, a recent study suggests selegeline use impacts white matter microstructure and could be neuroprotective. I know white matter abnormalities have been
It's often said that all of the treatments currently in use for Parkinson's offer symptomatic relief only, and do not affect underlying pathology. However, a recent study suggests selegeline use impacts white matter microstructure and could be neuroprotective. I know white matter abnormalities have been
Rufous2
in
Cure Parkinson's
6 months ago
Difference in levels-stress?
I've been on leventhyroxine for years for underactive thyroid. Had yearly check muddle of Feb. TSH 2.09. Had full bloods for something else (WRS) and levels are 0.36 by middle if April. I'm wondering if stress can cause TSH to go up or down? Dr. Says this is in normal range for lab- but normal
I've been on leventhyroxine for years for underactive thyroid. Had yearly check muddle of Feb. TSH 2.09. Had full bloods for something else (WRS) and levels are 0.36 by middle if April. I'm wondering if stress can cause TSH to go up or down? Dr. Says this is in normal range for lab- but normal
Itsallaboutcheese
in
Thyroid UK
3 months ago
rheumatoid arthritis
Has anyone had an operation on elbow from rheumatoid arthritis? Did it help?
Has anyone had an operation on elbow from rheumatoid arthritis? Did it help?
65_women
in
NRAS
3 months ago
Thyroid or menopause - which to sort first?
I've just checked the app, and the last of my blood tests are back. I definitely have started perimenopause and as per my last post I have high TPOab, high TSH (7.5 with high ref being 4.26), and lowish T4 (14.2 of a 12—22 range). I have symptoms that overlap the two conditions, but also symptoms that
I've just checked the app, and the last of my blood tests are back. I definitely have started perimenopause and as per my last post I have high TPOab, high TSH (7.5 with high ref being 4.26), and lowish T4 (14.2 of a 12—22 range). I have symptoms that overlap the two conditions, but also symptoms that
Heappestre
in
Thyroid UK
3 months ago
PA and Sjogren’s
I posted a few days ago about dry mouth and eyes, but since then my early sjogrens bloodwork has come back positive. I am terrified! Is there anyone else who has AIG/PA and also sjogrens? I feel desperately in need of some hope and guidance…in particular I’m wondering if injections have helped with SS
I posted a few days ago about dry mouth and eyes, but since then my early sjogrens bloodwork has come back positive. I am terrified! Is there anyone else who has AIG/PA and also sjogrens? I feel desperately in need of some hope and guidance…in particular I’m wondering if injections have helped with SS
Lhood08
in
Pernicious Anaemia Society
3 months ago
Google Research created an AI system that outperforms human doctors at diagnosing through conversation.
Google Research created an AI system that outperforms human doctors at diagnosing through conversation. https://blog.research.google/2024/01/amie-research-ai-system-for-diagnostic_12.html The Articulate Medical Intelligence Explorer (AMIE) is built on a Google LLM, and it's been optimized for "diagnostic
Google Research created an AI system that outperforms human doctors at diagnosing through conversation. https://blog.research.google/2024/01/amie-research-ai-system-for-diagnostic_12.html The Articulate Medical Intelligence Explorer (AMIE) is built on a Google LLM, and it's been optimized for "diagnostic
Darryl
Partner
in
Advanced Prostate Cancer
6 months ago
Flare
Thursday, my husband had his follow-up appointment with Oncologist. I was very alarmed at some of his blood test results. His PSA went up to 1600. Doctor said other blood work was to be expected. I researched surged in PSA and found this, The PSA flare is a well-known phenomenon. The post chemotherapy
Thursday, my husband had his follow-up appointment with Oncologist. I was very alarmed at some of his blood test results. His PSA went up to 1600. Doctor said other blood work was to be expected. I researched surged in PSA and found this, The PSA flare is a well-known phenomenon. The post chemotherapy
MsHope
in
Advanced Prostate Cancer
6 months ago
xtandi failing?
In September last year my PSA was 0.06. Three months later PSA was 0.09. I asked my doctor if xtandi was failing. He told me not necessarily, once your PSA reached its lowest point, it tends to go up and down before it settles down. He told me they would check my PSA in six weeks, six weeks later
In September last year my PSA was 0.06. Three months later PSA was 0.09. I asked my doctor if xtandi was failing. He told me not necessarily, once your PSA reached its lowest point, it tends to go up and down before it settles down. He told me they would check my PSA in six weeks, six weeks later
Echotango51
in
Advanced Prostate Cancer
6 months ago
Updated Lupus and the Skin booklet available now
We are proud to launch an updated version of our Lupus and the Skin information booklet. It is now available online and in hard copy from National Office. You can find more information about how the booklet was updated here: https://lupusuk.org.uk/updated-lupus-and-the-skin-booklet-available-now/ or
We are proud to launch an updated version of our Lupus and the Skin information booklet. It is now available online and in hard copy from National Office. You can find more information about how the booklet was updated here: https://lupusuk.org.uk/updated-lupus-and-the-skin-booklet-available-now/ or
Debbie_kinsey
Administrator
in
LUPUS UK
3 months ago
Barry
Hi, Diagnosed with advanced prostate cancer stage 4 gleeson score 4+4, having six monthly degarelix injections, had bad side effects on second injection upset stomach diorea feeling very drained, wondering if 3 monthly injections would be better less chemical in system?
Hi, Diagnosed with advanced prostate cancer stage 4 gleeson score 4+4, having six monthly degarelix injections, had bad side effects on second injection upset stomach diorea feeling very drained, wondering if 3 monthly injections would be better less chemical in system?
littlemount
in
Advanced Prostate Cancer
6 months ago
prescription
hi Every time I collect my prescription they give me my urso like this I was seeing if anybody else has this? I feel like when I change too the next box I get a pain on my liver side for a few days and itch a little more then it goes away same thing happens again when I start over again!
hi Every time I collect my prescription they give me my urso like this I was seeing if anybody else has this? I feel like when I change too the next box I get a pain on my liver side for a few days and itch a little more then it goes away same thing happens again when I start over again!
Lena2011
in
PBC Foundation
6 months ago
TIA in March
Hi, l recently had a mild TIA while in Cyprus where l live the treatment l received was excellent but the Neuroligist has prescribed Atvorstatin which l have found out shouldn’t be taken if you have an underactive Thyroid he dismissed this. Should l see my GP whilst l am in UK
Hi, l recently had a mild TIA while in Cyprus where l live the treatment l received was excellent but the Neuroligist has prescribed Atvorstatin which l have found out shouldn’t be taken if you have an underactive Thyroid he dismissed this. Should l see my GP whilst l am in UK
Tillybuds
in
Thyroid UK
3 months ago
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