hopefully it will be clinically tested soon
”For the study in Nature Communications, Mitrofanova's team developed computational algorithms to discover why the prostate cancer drug enzalutamide (sold under the brand name Xtandi) never works for some patients and why it eventually stops working in others.”
The question then becomes "Do I want to know this information?"...the added anxiety that some men suffer can be worse. I guess if you have the mental fortitude to handle bad news...this might be helpful, otherwise it can be unhelpful.
I understand what you mean even if I think there would be ethical reasons why doctor would be forced to tell you the truth, but I think the advantages are way more important. There are two advantages, the first one is not to let you waste time with a line of treatment that won't work, the second and more important one is that understanding why it does not work gave them an idea about how to make it work de novo or how to restore enza effect when a patient stops responding.
"But there was a silver lining: Reducing NME2 and, thus, MYC levels restored the efficacy of enzalutamide in cancers that had grown resistant to its effects."
They are already thinking about a blocker or a CRISPR genetic knockout. Ok, this test taken tomorrow would give you just the first advantage, but maybe in one year....
Thanks for sharing!
The food to avoid for a patient with advanced prostate cancer
Thoughts on these recommended supplements
Enzalutamide working for my dad
