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Use of Rx drugs and botanical compounds to prevent chemo drug-resistance with Docetaxel.
The anti-diabetic medication has low cost and minimal side effects, and it is known to decrease prostate cancer incidence and improve time to
castration
resistance and survival in prostate cancer patients who are diabetic.
The anti-diabetic medication has low cost and minimal side effects, and it is known to decrease prostate cancer incidence and improve time to
castration
resistance and survival in prostate cancer patients who are diabetic.
chillpill7
in
Advanced Prostate Cancer
5 years ago
Would anybody know if you could take CABAZITAZEL and still continue taking ZYTIGA, LUPRON and ZOMETA?
Second part of the question was: I’m someone who has already reached the stage of being Metastatic
Castration
Resistant Prostate Cancer, I very much still want to qualify for drugs like CABAZITAXEL if I can be.
Second part of the question was: I’m someone who has already reached the stage of being Metastatic
Castration
Resistant Prostate Cancer, I very much still want to qualify for drugs like CABAZITAXEL if I can be.
Xtandie
in
Advanced Prostate Cancer
5 years ago
FDA Approves Apalutamide for mHSPC
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-apalutamide-metastatic-
castration
-sensitive-prostate-cancer Interesting, Xtandi got a head start from Erleada, perhaps competition will lower the cost...
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-apalutamide-metastatic-
castration
-sensitive-prostate-cancer Interesting, Xtandi got a head start from Erleada, perhaps competition will lower the cost...
DarkEnergy
in
Advanced Prostate Cancer
5 years ago
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Cabazitaxel Plus Carboplatin for the Treatment of Men With Metastatic Castration-Resistant Prostate Cancer
METHODS We did a phase 1-2, open label, randomised study at two centres in men with progressive metastatic
castration
-resistant prostate cancer.
METHODS We did a phase 1-2, open label, randomised study at two centres in men with progressive metastatic
castration
-resistant prostate cancer.
Balsam01
in
Advanced Prostate Cancer
5 years ago
ADT vs Castration Should I hold off.
Considering
castration
. I am going to turn 58 in December March 2020 will be five years in the fight. Farm 15
Considering
castration
. I am going to turn 58 in December March 2020 will be five years in the fight. Farm 15
farm15
in
Advanced Prostate Cancer
5 years ago
Digitoxin
"
Castration
Resistant Prostate Cancer (CRPC) is thought to be driven by a collaborative mechanism between TNFα/NFκB and TGFβ signaling, leading to inflammation, Epithelial-to-Mesenchymal-Transition (EMT), and metastasis."
"
Castration
Resistant Prostate Cancer (CRPC) is thought to be driven by a collaborative mechanism between TNFα/NFκB and TGFβ signaling, leading to inflammation, Epithelial-to-Mesenchymal-Transition (EMT), and metastasis."
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Caregiver research for stage 4 prostate cancer OR non-metastatic castrate resistant prostate cancer
Find A Cure Panel has some new online caregivers research of men who have stage 4 prostate cancer or are non metastatic
castration
resistant (NMCR) Your loved must be on current or recent treatment for his PC.
Find A Cure Panel has some new online caregivers research of men who have stage 4 prostate cancer or are non metastatic
castration
resistant (NMCR) Your loved must be on current or recent treatment for his PC.
Darryl
Partner
in
Advanced Prostate Cancer
5 years ago
Dream Cruise
I've never been told
castration
resistant but I assume so. His pathology report showed 12 of 12 cores 5+4. We all know what that means. Why the heck would they NOT approve Zytiga? Any words of wisdom would be appreciated! Love you all! Barb PS...
I've never been told
castration
resistant but I assume so. His pathology report showed 12 of 12 cores 5+4. We all know what that means. Why the heck would they NOT approve Zytiga? Any words of wisdom would be appreciated! Love you all! Barb PS...
Brbnbrn
in
Advanced Prostate Cancer
5 years ago
Prostate Cancer Germline Genetics in Clinical Practice
However, there is strong evidence that patients with metastatic,
castration
resistant prostate cancer who have DNA damage repair defects respond positively to targeting PARP enzymes.
However, there is strong evidence that patients with metastatic,
castration
resistant prostate cancer who have DNA damage repair defects respond positively to targeting PARP enzymes.
Balsam01
in
Advanced Prostate Cancer
5 years ago
Oral docetaxel
They completed a Phase I trial with prostate cancer patients and apparently did well enough that they say that they've started a Phase II with breast cancer patients and are planning a Phase IIb clinical trial for metastatic
castration
resistant prostate cancer - for which they say they have FDA approval
They completed a Phase I trial with prostate cancer patients and apparently did well enough that they say that they've started a Phase II with breast cancer patients and are planning a Phase IIb clinical trial for metastatic
castration
resistant prostate cancer - for which they say they have FDA approval
AlanMeyer
in
Advanced Prostate Cancer
5 years ago
Cabazitaxel Plus Carboplatin for the Treatment of Men With Metastatic Castration-Resistant Prostate Cancer
"TAKE-HOME MESSAGE This phase I/II trial evaluated the combination of cabazitaxel and carboplatin for patients with metastatic
castration
-resistant prostate cancer.
"TAKE-HOME MESSAGE This phase I/II trial evaluated the combination of cabazitaxel and carboplatin for patients with metastatic
castration
-resistant prostate cancer.
snoraste
in
Advanced Prostate Cancer
5 years ago
Abiraterone in "High-" and "Low-risk" Metastatic Hormone-sensitive PCa.
"
Castration
therapy" would perhaps be clearer. The term CRPC (castrate-resistant PCa) is clear enough, but what is the term for failing Abi monotherapy or Abi+classic ADT?
"
Castration
therapy" would perhaps be clearer. The term CRPC (castrate-resistant PCa) is clear enough, but what is the term for failing Abi monotherapy or Abi+classic ADT?
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer
"The efficacy and safety of cabazitaxel, as compared with an androgen-signaling–targeted inhibitor (abiraterone or enzalutamide), in patients with metastatic
castration
-resistant prostate cancer who were previously treated with docetaxel and had progression within 12 months while receiving the alternative
"The efficacy and safety of cabazitaxel, as compared with an androgen-signaling–targeted inhibitor (abiraterone or enzalutamide), in patients with metastatic
castration
-resistant prostate cancer who were previously treated with docetaxel and had progression within 12 months while receiving the alternative
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Need Advice-Bipolar Androgen Therapy
He has
castration
-resistant prostate cancer with progression despite abiraterone, enzalutamide, and docetaxel chemotherapy and radium-223. His alkaline phosphate were about 1500 prior to the start and now they are almost normal. However his PSA remains around 500.
He has
castration
-resistant prostate cancer with progression despite abiraterone, enzalutamide, and docetaxel chemotherapy and radium-223. His alkaline phosphate were about 1500 prior to the start and now they are almost normal. However his PSA remains around 500.
Amandaslp78
in
Advanced Prostate Cancer
5 years ago
CRPC & 'Drug Repositioning'
Screening of Drug Repositioning Candidates for
Castration
Resistant Prostate Cancer. Kim IW1, Kim JH1, Oh JM1. Author information 1 College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul, South Korea.
Screening of Drug Repositioning Candidates for
Castration
Resistant Prostate Cancer. Kim IW1, Kim JH1, Oh JM1. Author information 1 College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul, South Korea.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Radium-223 in Clinical Practice. Video
"In conclusion, the ERA-223 study highlights the importance of bone health, a topic in need of quality improvement, as it represents an area of high-value care for men with
castration
-resistant prostate cancer.
"In conclusion, the ERA-223 study highlights the importance of bone health, a topic in need of quality improvement, as it represents an area of high-value care for men with
castration
-resistant prostate cancer.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
New prostate cancer treatment concept
Recent clinical trials have hinted that combining immunotherapy and radiation therapy may be a powerful treatment approach for
castration
-resistant prostate cancer. https://medicalxpress.com/news/2019-08-prostate-cancer-treatment-concept.html
Recent clinical trials have hinted that combining immunotherapy and radiation therapy may be a powerful treatment approach for
castration
-resistant prostate cancer. https://medicalxpress.com/news/2019-08-prostate-cancer-treatment-concept.html
George71
in
Advanced Prostate Cancer
5 years ago
PSMA Heterogeneity and DNA Repair Defects in Prostate Cancer
The expression of membranous PSMA was heterogeneous, more common in
castration
-resistant disease, and associated with a higher Gleason score (P=.04), and worse overall survival (P=.006).
The expression of membranous PSMA was heterogeneous, more common in
castration
-resistant disease, and associated with a higher Gleason score (P=.04), and worse overall survival (P=.006).
Balsam01
in
Advanced Prostate Cancer
5 years ago
PSMA Heterogeneity and DNA Repair Defects in Prostate Cancer
The expression of membranous PSMA was heterogeneous, more common in
castration
-resistant disease, and associated with a higher Gleason score (P=.04), and worse overall survival (P=.006).
The expression of membranous PSMA was heterogeneous, more common in
castration
-resistant disease, and associated with a higher Gleason score (P=.04), and worse overall survival (P=.006).
Balsam01
in
Advanced Prostate Cancer
5 years ago
PSMA Heterogeneity and DNA Repair Defects in Prostate Cancer
The expression of membranous PSMA was heterogeneous, more common in
castration
-resistant disease, and associated with a higher Gleason score (P=.04), and worse overall survival (P=.006).
The expression of membranous PSMA was heterogeneous, more common in
castration
-resistant disease, and associated with a higher Gleason score (P=.04), and worse overall survival (P=.006).
snoraste
in
Advanced Prostate Cancer
5 years ago
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