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Low-T is associated with worse Prostate Cancer Specific Mortality probability after 6 months of ADT: Part III
Here are comparisons of the
Prostate Cancer Specific Mortality (PCSM) probability (%
) for two different testosterone levels (
Low-T and Normal-T
) and four different
Times After PSA Failure
from the Kaplan-Meier plot previously posted. (Atkins 2018). The median testosterone for
Here are comparisons of the
Prostate Cancer Specific Mortality (PCSM) probability (%
) for two different testosterone levels (
Low-T and Normal-T
) and four different
Times After PSA Failure
from the Kaplan-Meier plot previously posted. (Atkins 2018). The median testosterone for
janebob99
in
Prostate Cancer Network
4 months ago
Low-T is associated with worse Prostate Cancer Specific Mortality probability after 6 months of ADT: Part II
Here are comparisons of the Prostate Cancer Specific Mortality (PCSM) probability (%) for two different testosterone levels (Low-T and Normal-T)and three different Times After PSA Failure from Atkins (2018). he median testosterone for the Low-T group is T = 162 ng/dL [120-236], and I assumed an average
Here are comparisons of the Prostate Cancer Specific Mortality (PCSM) probability (%) for two different testosterone levels (Low-T and Normal-T)and three different Times After PSA Failure from Atkins (2018). he median testosterone for the Low-T group is T = 162 ng/dL [120-236], and I assumed an average
janebob99
in
Prostate Cancer Network
4 months ago
GP appointment
An update from my last posts.I went to see my gp yesterday waited 2 weeks for a face to face appointment , I asked about HRT and was told at my age there would be to many risks and it would have any benifits to my health, also as I had to go to A&E on Monday funny turn at 4 am, gp said go to A&E, suspected
An update from my last posts.I went to see my gp yesterday waited 2 weeks for a face to face appointment , I asked about HRT and was told at my age there would be to many risks and it would have any benifits to my health, also as I had to go to A&E on Monday funny turn at 4 am, gp said go to A&E, suspected
Dawney63
in
Thyroid UK
4 months ago
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WHAT ARE THE CURRENT EFFECTIVE SALVAGE TREATMENTS IN CASE OF A REOCCURRENCE IF YOU HAVE HAD SBRT,IMRT, WITH PLACEMENT OF GOLD BARS?
It appears that if you had SBRT or like myself IMRT and you were given
gold markers
you cannot do any of the following
salvage treatments in case of a reoccurrence
: Proton therapy, Hifu, Tulsa Pro , Etc. Is this true???? Again a significant fact left out before treatment...
In addition
It appears that if you had SBRT or like myself IMRT and you were given
gold markers
you cannot do any of the following
salvage treatments in case of a reoccurrence
: Proton therapy, Hifu, Tulsa Pro , Etc. Is this true???? Again a significant fact left out before treatment...
In addition
JWS13
in
Advanced Prostate Cancer
6 months ago
bilateral oophorectomy at 34
Hi all, I am looking to hear from real people (you folks on this forum) about your experiences for a bilateral oophorectomy. I have been suffering with debilitating endometriosis symptoms for more than a decade and on Monday March 4th I saw a consultant about my treatment steps. She was the surgeon
Hi all, I am looking to hear from real people (you folks on this forum) about your experiences for a bilateral oophorectomy. I have been suffering with debilitating endometriosis symptoms for more than a decade and on Monday March 4th I saw a consultant about my treatment steps. She was the surgeon
HomebodyFig
in
Endometriosis UK
4 months ago
Fears confirmed
I posted previously on this long and tortuous journey to ( almost) a diagnosis. Almost because my concierge PCP gave me a heads up on the biopsy report which hasn’t been posted on my digital chart and I haven’t yet heard from my Urologist/ Onocologist. It’s been 4 mos since my annual checkup said my
I posted previously on this long and tortuous journey to ( almost) a diagnosis. Almost because my concierge PCP gave me a heads up on the biopsy report which hasn’t been posted on my digital chart and I haven’t yet heard from my Urologist/ Onocologist. It’s been 4 mos since my annual checkup said my
Willie51
in
Prostate Cancer And Gay Men
4 months ago
Medicare Part D decision
So, I'm going on Medicare in April. I've enrolled in the Blue Cross Plan G Supplement plan and am now trying to decide which Part D plan to get for meds. At the moment my main concern is what it's going to cost for my new Abiraterone prescription. It looks like BCBS is going to be too expensive. Their
So, I'm going on Medicare in April. I've enrolled in the Blue Cross Plan G Supplement plan and am now trying to decide which Part D plan to get for meds. At the moment my main concern is what it's going to cost for my new Abiraterone prescription. It looks like BCBS is going to be too expensive. Their
fireandice123
in
Advanced Prostate Cancer
4 months ago
Scary PSA results
I was diagnosed in October 2023 with Gleason 4+5=9. Tissue came from TURP. PSA was 11.8. PSMA Pet was negative for METS. Started ADT on November 9. Did 28 sessions of IMRT from Feb 12, 2024, to Mar 21, 2024. Nadir was .8 on Mar 26 and then the last two have been 1.5 and 3.1. RO said 2.8 was the
I was diagnosed in October 2023 with Gleason 4+5=9. Tissue came from TURP. PSA was 11.8. PSMA Pet was negative for METS. Started ADT on November 9. Did 28 sessions of IMRT from Feb 12, 2024, to Mar 21, 2024. Nadir was .8 on Mar 26 and then the last two have been 1.5 and 3.1. RO said 2.8 was the
7OaksTom
in
Advanced Prostate Cancer
25 days ago
Relugolix/Orgovyx or Enzalutamide/Xtandi?
Good morning, all. I have updated my profile with my husband's history. But, long story short, he has been on ADT vacation for 13 months following succesful treatment of metastatic disease with Triplet Therapy (six rounds of Docetaxel, Lupron, and first Abieraterone plus Prednisone and then he switched
Good morning, all. I have updated my profile with my husband's history. But, long story short, he has been on ADT vacation for 13 months following succesful treatment of metastatic disease with Triplet Therapy (six rounds of Docetaxel, Lupron, and first Abieraterone plus Prednisone and then he switched
FaithOverFear104
in
Advanced Prostate Cancer
4 months ago
Feeling let down
Just a bit of a rant really as feeling let down by the system. I’ve been back and forth to the GP’s over the years with Raynuards, rosacea, recently a sun spot that turned cancerous, depression, fainting etc and no one up until me doing my research has ever joined the all the constellation of symptoms
Just a bit of a rant really as feeling let down by the system. I’ve been back and forth to the GP’s over the years with Raynuards, rosacea, recently a sun spot that turned cancerous, depression, fainting etc and no one up until me doing my research has ever joined the all the constellation of symptoms
Fizzwhizz
in
Thyroid UK
4 months ago
living with panic disorder- any tips?
I was diagnosed with panic disorder in mid 2022, it was a sudden occurance that traumatized me I fear for life. I had panic attacks that lasted from the moment I woke up to the minute I fell asleep, sometimes waking from them which lasted weeks before I looked for professional help. I went to intensive
I was diagnosed with panic disorder in mid 2022, it was a sudden occurance that traumatized me I fear for life. I had panic attacks that lasted from the moment I woke up to the minute I fell asleep, sometimes waking from them which lasted weeks before I looked for professional help. I went to intensive
Takeabath
in
Anxiety and Depression Support
9 months ago
Magnesium, zinc and calcium
Nearly a year after ADT and all clear with testosterone recovering well. Been advised by a fellow runner to try a supplement of magnesium, zinc and calcium. The Onco has no objections. Are there reasons no too? Thank you.
Nearly a year after ADT and all clear with testosterone recovering well. Been advised by a fellow runner to try a supplement of magnesium, zinc and calcium. The Onco has no objections. Are there reasons no too? Thank you.
Runner1957
in
Prostate Cancer Network
4 months ago
Testosterone volatility
My testosterone was measured @ 490 in 2014 when I was DX with PCa Gleason 6, it was measured again in 2016 at 463. It was not measured again until after I started on ADT and it has been >7 ever since. Is there a way for me to extrapolate what it would have been in 2021 when I was DX with Gleason
My testosterone was measured @ 490 in 2014 when I was DX with PCa Gleason 6, it was measured again in 2016 at 463. It was not measured again until after I started on ADT and it has been >7 ever since. Is there a way for me to extrapolate what it would have been in 2021 when I was DX with Gleason
Scout4answers
in
Prostate Cancer Network
4 months ago
Unsure about increasing T3
Hi Everyone, I’ve had my appointment with my thyroid specialist today and she wants me to increase my T3 from 15mcg a day to 25mcg a day and keep levo at 100mcg. However I’m really hesitant to do this as last time I increased my T3 (see my original post below) I got my T4 to 6 and felt awful. Plus I
Hi Everyone, I’ve had my appointment with my thyroid specialist today and she wants me to increase my T3 from 15mcg a day to 25mcg a day and keep levo at 100mcg. However I’m really hesitant to do this as last time I increased my T3 (see my original post below) I got my T4 to 6 and felt awful. Plus I
Fallleaves
in
Thyroid UK
4 months ago
Hypo, Hashi's, Menopause & Testosterone
My last sex hormone blood test showed my testosterone at [u]
1.91!
[/u]
(range of 0.10-1.42) This concerns my Endo doc who has been amazing treating my thyroid issues, but has now informed me that AFTER
age 60
you shouldn't BEGIN hrt. 😪 So, that's out of the question for me since
My last sex hormone blood test showed my testosterone at [u]
1.91!
[/u]
(range of 0.10-1.42) This concerns my Endo doc who has been amazing treating my thyroid issues, but has now informed me that AFTER
age 60
you shouldn't BEGIN hrt. 😪 So, that's out of the question for me since
wavedancers
in
Thyroid UK
4 months ago
Genomics
HI all, After a progression 2 years on Arimadex, Ibrance my dear partner has had a liver biopsy and we are doing genomics testing, around $3.3k. 500 gene plate? Awaiting results but after a second opinion , (lady Onc, more caring, smart) Fulvescant has been prescribed. The other prescribed Tamoxifen
HI all, After a progression 2 years on Arimadex, Ibrance my dear partner has had a liver biopsy and we are doing genomics testing, around $3.3k. 500 gene plate? Awaiting results but after a second opinion , (lady Onc, more caring, smart) Fulvescant has been prescribed. The other prescribed Tamoxifen
muzzatron
in
SHARE Metastatic Breast Cancer
9 months ago
Low testosterone is associated with extremely poor survival metrics, post-ADT.
These companion plots compare: (A) median survival times, (B) PSA doubling times, and (C) Time to PSA Failure for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable
These companion plots compare: (A) median survival times, (B) PSA doubling times, and (C) Time to PSA Failure for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable
janebob99
in
Prostate Cancer Network
4 months ago
Low Testosterone reduces Survival by a huge amount.
This plot compares prostate cancer specific mortality probability versus time for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable intermediate risk who underwent
This plot compares prostate cancer specific mortality probability versus time for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable intermediate risk who underwent
janebob99
in
Prostate Cancer Network
4 months ago
My own PSA values over time: 70% drop in just 3 months on Dutasteride and no ADT
Here are my own PSA values versus time plot. You can see there is an exponential rise in PSA starting at around 6/1/23, and doubling from PSA = 5 to 10 in about 8 months. My MRI at PSA = 10 showed a T3a tumor about 1.3 cm long (PIRADS 5). A subsequent targeted biopsy showed Gleason 3+4 in 4 cores,
Here are my own PSA values versus time plot. You can see there is an exponential rise in PSA starting at around 6/1/23, and doubling from PSA = 5 to 10 in about 8 months. My MRI at PSA = 10 showed a T3a tumor about 1.3 cm long (PIRADS 5). A subsequent targeted biopsy showed Gleason 3+4 in 4 cores,
janebob99
in
Prostate Cancer Network
4 months ago
Doubling Times and PSA acceleration - Part II
This is a more realistic schematic plot of PSA levels increasing over time at an ever faster rate (acceleration). What could cause this? My theory is that as the tumor grows, the number of androgen receptors (ARs) increases proportionally. That makes sense...more PCa cells inside a tumor...more ARs
This is a more realistic schematic plot of PSA levels increasing over time at an ever faster rate (acceleration). What could cause this? My theory is that as the tumor grows, the number of androgen receptors (ARs) increases proportionally. That makes sense...more PCa cells inside a tumor...more ARs
janebob99
in
Prostate Cancer Network
4 months ago
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