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NE3107 added to levodopa enhances motor, non-motor benefits
“These data suggest that NE3107 as an adjunct therapy to levodopa may hold promise in ameliorating specific non-motor symptoms of Parkinson’s Disease, particularly in sleep/fatigue and restlessness of the legs,” Joseph Palumbo, MD, BioVie’s chief medical officer, said in a company press release. https
“These data suggest that NE3107 as an adjunct therapy to levodopa may hold promise in ameliorating specific non-motor symptoms of Parkinson’s Disease, particularly in sleep/fatigue and restlessness of the legs,” Joseph Palumbo, MD, BioVie’s chief medical officer, said in a company press release. https
Farooqji
in
Cure Parkinson's
6 months ago
Citicoline: "patients treated with citicoline experienced a significant worsening 45 days after the medication was discontinued". Updated.
This statement appears in a review that was published here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548481/ It is attributed to a study published in a book on citicoline in 1985. I've been unable to locate a copy of this book either online, for sale or to borrow from a library. Book: Zappia
This statement appears in a review that was published here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548481/ It is attributed to a study published in a book on citicoline in 1985. I've been unable to locate a copy of this book either online, for sale or to borrow from a library. Book: Zappia
park_bear
in
Cure Parkinson's
6 months ago
dopamine pump
hi I was wondering if this new levodopa pump can give more stable levels of the medicine instead of using it in advance stages of Parkinson why shouldn't,t ,t they use it earlier??
hi I was wondering if this new levodopa pump can give more stable levels of the medicine instead of using it in advance stages of Parkinson why shouldn't,t ,t they use it earlier??
Rupa88
in
Cure Parkinson's
6 months ago
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Nicht nur Nachts im Bett
Hi, 2022 würde rls vom Neurologen festgestellt. Die Symptome selber habe ich seit 2018. Zu Anfangs wurde Levodopa 100mg/25mg verschrieben. Nach einiger Zeit Neupropflaster, Rotigotin 2mg/24h aber die hatte ich selber abgesetzt. Ich wechselte den Arzt und der verschrieb sofort pramipexol 0,18mg. Zu Beginn
Hi, 2022 würde rls vom Neurologen festgestellt. Die Symptome selber habe ich seit 2018. Zu Anfangs wurde Levodopa 100mg/25mg verschrieben. Nach einiger Zeit Neupropflaster, Rotigotin 2mg/24h aber die hatte ich selber abgesetzt. Ich wechselte den Arzt und der verschrieb sofort pramipexol 0,18mg. Zu Beginn
Imanazudici
in
Restless Legs Syndrome
6 months ago
Subcutaneous Levodopa Pump Available in Canada
https://thelaymanspeaks.medium.com/offering-hope-to-those-living-with-advanced-parkinsons-disease-ec8afc27feab?sk=397b46dbb040862e2bb24aa012b0c365
https://thelaymanspeaks.medium.com/offering-hope-to-those-living-with-advanced-parkinsons-disease-ec8afc27feab?sk=397b46dbb040862e2bb24aa012b0c365
pdpatient
in
Cure Parkinson's
6 months ago
Recent study on Levodopa
Read the article at https://www.tandfonline.com/doi/full/10.1080/14740338.2023.2227096 Expert opinion No strong evidence exists to support use of a specific adjunctive treatment for improving Off time. Only one medication has demonstrated improvement in dyskinesia in levodopa-treated PD patients
Read the article at https://www.tandfonline.com/doi/full/10.1080/14740338.2023.2227096 Expert opinion No strong evidence exists to support use of a specific adjunctive treatment for improving Off time. Only one medication has demonstrated improvement in dyskinesia in levodopa-treated PD patients
pdpatient
in
Cure Parkinson's
6 months ago
Sharing my recent journey with Parkinson's-induced insomnia
Hello everyone, Parkinson's-induced insomnia is a very common problem. I just wanted to share my recent experience, in the hope that it might help others I was diagnosed 4 years ago (symptomatic for 6 years) and, until recently, I would wake up a few times at night, but a few mg of melatonin would
Hello everyone, Parkinson's-induced insomnia is a very common problem. I just wanted to share my recent experience, in the hope that it might help others I was diagnosed 4 years ago (symptomatic for 6 years) and, until recently, I would wake up a few times at night, but a few mg of melatonin would
Michel0220
in
Cure Parkinson's
7 months ago
AAN 2023: Amneal’s IPX203 shows promise for Parkinson’s disease patients
Academy of Neurology (AAN) 2023 Annual Meeting, Amneal presented new data evaluating IPX203 (
carbidopa
+
levodopa
, CD/LD) in a nine-month open-label extension (OLE) study in Parkinson’s disease (PD) patients with motor fluctuations (NCT03877510).
Academy of Neurology (AAN) 2023 Annual Meeting, Amneal presented new data evaluating IPX203 (
carbidopa
+
levodopa
, CD/LD) in a nine-month open-label extension (OLE) study in Parkinson’s disease (PD) patients with motor fluctuations (NCT03877510).
Farooqji
in
Cure Parkinson's
1 year ago
Insomnia
Currently I'm on
levodopa
/
carbidopa
, safinamide and opicapona. Do you think It can be related with B1? Or maybe DBS tunning? Thanks for any advice.
Currently I'm on
levodopa
/
carbidopa
, safinamide and opicapona. Do you think It can be related with B1? Or maybe DBS tunning? Thanks for any advice.
carlosgarcia2048
in
Cure Parkinson's
5 months ago
Withdrawal when trying to reduce Levodopa
I was wondering if PwP who have used Levodopa long term and in high doses have ever experienced withdrawal symptoms when tapering or stopping the treatment with Levodopa (L/C or Levodopa/Benzarazide).If you have, I would be grateful if you could describe the withdrawal symptoms you have had, and how
I was wondering if PwP who have used Levodopa long term and in high doses have ever experienced withdrawal symptoms when tapering or stopping the treatment with Levodopa (L/C or Levodopa/Benzarazide).If you have, I would be grateful if you could describe the withdrawal symptoms you have had, and how
Daisies22
in
Cure Parkinson's
7 months ago
Riboflavin (b2) supplementation is a no-brainer for Parkinsons
Riboflavin (b2) is a complete no-brainer. 0 side effects and dirt cheap. Especially if your second and third toes any toenails are full of fungus/athletes foot. The Chinese believe that your second and third toe is a place where toxins leave the body. The Chinese believe PD is “stuck” in fight or
Riboflavin (b2) is a complete no-brainer. 0 side effects and dirt cheap. Especially if your second and third toes any toenails are full of fungus/athletes foot. The Chinese believe that your second and third toe is a place where toxins leave the body. The Chinese believe PD is “stuck” in fight or
38yroldmale
in
Cure Parkinson's
7 months ago
Vodobatinib
Anyone heard about this? Note on *SPARC's Vodobatinib* for *Parkinson's Disease*: SPARC, a pioneering force in the pharmaceutical arena, is making significant strides with its flagship *Neurological* program asset, Vodobatinib. Currently, Vodobatinib is undergoing trials for three critical indications
Anyone heard about this? Note on *SPARC's Vodobatinib* for *Parkinson's Disease*: SPARC, a pioneering force in the pharmaceutical arena, is making significant strides with its flagship *Neurological* program asset, Vodobatinib. Currently, Vodobatinib is undergoing trials for three critical indications
JayPwP
in
Cure Parkinson's
7 months ago
DIY Parkinson's Glove Users - How are you adjusting?
Hi I'm interested in anecdotal information from those who are using a DIY version of a vibrotactile glove specifically on how you have adjusted (or not adjusted) your medication over the course of your glove testing. I'm trying to see if there are any trends that would imply that this is replacing
Hi I'm interested in anecdotal information from those who are using a DIY version of a vibrotactile glove specifically on how you have adjusted (or not adjusted) your medication over the course of your glove testing. I'm trying to see if there are any trends that would imply that this is replacing
JacksMomTX
in
Cure Parkinson's
7 months ago
Citicoline Warning
Citicoline and choline contain the trimethylamine structure which can be detached by gut bacteria into standalone trimethylamine. Trimethylamine is toxic. Excessive intake of choline results in a dramatic increase in the risk of cardiovascular disease. My writing on this subject here: https://tinyurl.com
Citicoline and choline contain the trimethylamine structure which can be detached by gut bacteria into standalone trimethylamine. Trimethylamine is toxic. Excessive intake of choline results in a dramatic increase in the risk of cardiovascular disease. My writing on this subject here: https://tinyurl.com
park_bear
in
Cure Parkinson's
7 months ago
Easy-to-use inhaled levodopa system readying request for US approval
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
Farooqji
in
Cure Parkinson's
7 months ago
Seeking Advise
Hello fellow Parkies I am in dire need for some advise regarding the dosage of my medications. I am in my 7th year since diagnosed with Parkinson's and I have for most of the time been on Madopar (200mg of levodopa and 50mg of benserazide). I started of with half a tablet 3 x per day, later increased
Hello fellow Parkies I am in dire need for some advise regarding the dosage of my medications. I am in my 7th year since diagnosed with Parkinson's and I have for most of the time been on Madopar (200mg of levodopa and 50mg of benserazide). I started of with half a tablet 3 x per day, later increased
Mischl
in
Cure Parkinson's
7 months ago
Mayo Clinics' take on Levodopa
Read the article here : https://www.mayoclinicproceedings.org/article/S0025-6196(20)30152-X/fulltext
Read the article here : https://www.mayoclinicproceedings.org/article/S0025-6196(20)30152-X/fulltext
pdpatient
in
Cure Parkinson's
7 months ago
Interesting Article: Promising new remedies for Parkinson's disease
Update:
I read and researched as I was posting this. I am happy they put NR and PEA in their article, but I think they got a little over their skis stating they had found a "
A dynamic quartet
" [u]
Update Again! Please see Park Bear's Citicoline Warning
[/u] https://healthunlocked.com
Update:
I read and researched as I was posting this. I am happy they put NR and PEA in their article, but I think they got a little over their skis stating they had found a "
A dynamic quartet
" [u]
Update Again! Please see Park Bear's Citicoline Warning
[/u] https://healthunlocked.com
Bolt_Upright
in
Cure Parkinson's
7 months ago
HELP finding my pills! 2 years on Carbidopa/Levadopa ER 25/100. My pharmacy changed from Accord (pink pills) to blue pills that don’t work.
i can’t find the Accord (generic) pills near me here in Orlando FL. I’m wondering if they are discontinued. There’s some rumblings in the internet of the 25/100 being discontinued I tried to contact Accord manufacturer in NC but I’ll need to call tomorrow. I have the prescription and pills for a
i can’t find the Accord (generic) pills near me here in Orlando FL. I’m wondering if they are discontinued. There’s some rumblings in the internet of the 25/100 being discontinued I tried to contact Accord manufacturer in NC but I’ll need to call tomorrow. I have the prescription and pills for a
Nikosmom
in
Cure Parkinson's
9 months ago
MDDoctors
Do MDD have the time to look at the research that's going on in treating Parkinsons?Do they dismiss anything that's not peer reviewed. e.g My wife who's being treated for Parkinsons, has for the past year, suffered, leg/ calf cramp, wher she has to stop a few times and basically try and stretch it off
Do MDD have the time to look at the research that's going on in treating Parkinsons?Do they dismiss anything that's not peer reviewed. e.g My wife who's being treated for Parkinsons, has for the past year, suffered, leg/ calf cramp, wher she has to stop a few times and basically try and stretch it off
Allypally49
in
Cure Parkinson's
7 months ago
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