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Carbidopa / Levodopa
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Anyone else not helped by dopamine agonists?
Hi Everyone - I've been on levodopa (specifically Sinemet Plus three times a day) for three and a half years and it has worked very well but now I am starting to get worse symptoms again: slow movement, weakness, stooped gait, poor motor skills etc. As I am still fairly young for Parkinsons (soon to
Hi Everyone - I've been on levodopa (specifically Sinemet Plus three times a day) for three and a half years and it has worked very well but now I am starting to get worse symptoms again: slow movement, weakness, stooped gait, poor motor skills etc. As I am still fairly young for Parkinsons (soon to
potbatch
in
Cure Parkinson's
6 years ago
Mucuna Pruriens in Parkinson's disease, dosages and effects, A double-blind, randomized, controlled, crossover human study (2017)
Update 2018: Similar Trial with
Carbidopa
(CD) instead of Benserazide reported gastrointestinal issues https://www.ncbi.nlm.nih.gov/pubmed/29352722 "Daily intake of MP was associated with a variable clinical response, especially in terms of tolerability.
Update 2018: Similar Trial with
Carbidopa
(CD) instead of Benserazide reported gastrointestinal issues https://www.ncbi.nlm.nih.gov/pubmed/29352722 "Daily intake of MP was associated with a variable clinical response, especially in terms of tolerability.
Greenday
in
Cure Parkinson's
7 years ago
Did you know that Levodopa depletes SAM-e?
Here is the article: http://www.acupuncturebrooklyn.com/alternative-health/sam-e-for-parkinsons
Here is the article: http://www.acupuncturebrooklyn.com/alternative-health/sam-e-for-parkinsons
faridaro
in
Cure Parkinson's
7 years ago
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Will taking mucuna pruriens (instead of Sinemet) prevent peripheral neuropathy?
Is the peripheral neuropathy a side effect of Carbidopa, or a reaction to the downtime from Sinemet? My friend had been using Mucuna Pruriens, but I recently discovered it only contained 15% L-dopa and would like to get a higher grade, maybe 98% though I wonder if a 40% powder or capsule would work better
Is the peripheral neuropathy a side effect of Carbidopa, or a reaction to the downtime from Sinemet? My friend had been using Mucuna Pruriens, but I recently discovered it only contained 15% L-dopa and would like to get a higher grade, maybe 98% though I wonder if a 40% powder or capsule would work better
yeramian
in
Cure Parkinson's
7 years ago
My daily dose
MY DAILY DOSE Well, it's been almost 10 years since I was diagnosed with Parkinson's Disease. My toes are on a constant state of numbness combined with my toes cramping and trying to curl under. I take Gabapentin 600mg 4xs per day. It does nothing..... for my toes anyhow! I am now on the following cocktail
MY DAILY DOSE Well, it's been almost 10 years since I was diagnosed with Parkinson's Disease. My toes are on a constant state of numbness combined with my toes cramping and trying to curl under. I take Gabapentin 600mg 4xs per day. It does nothing..... for my toes anyhow! I am now on the following cocktail
joyceann
in
Cure Parkinson's
7 years ago
CITICOLIN and neurotransmitters
https://rover.ebay.com/rover/0/0/0?mpre=https%3A%2F%2Fwww.ebay.com%2Fulk%2Fitm%2F263172798293 I am reposting the thread, by Aspergian, I missed it completely till now. Sounds like you can reduce the amount of levodopa that you're taking and still get very good results or better. If you search for" excellent
https://rover.ebay.com/rover/0/0/0?mpre=https%3A%2F%2Fwww.ebay.com%2Fulk%2Fitm%2F263172798293 I am reposting the thread, by Aspergian, I missed it completely till now. Sounds like you can reduce the amount of levodopa that you're taking and still get very good results or better. If you search for" excellent
parkie13
in
Cure Parkinson's
7 years ago
Apomorphine Sublingual Film Passes Phase lll Trial - New Option to Smooth "Off" Troughs
"Sunovion Pharmaceuticals’ below-the-tongue version of a Parkinson’s therapy was able to ease patients’ movement difficulties after the standard therapy levodopa wore off, a Phase 3 clinical trial showed. "Apomorphine, also known as APL-130277, works by mimicking dopamine’s activity in the brain. "Between
"Sunovion Pharmaceuticals’ below-the-tongue version of a Parkinson’s therapy was able to ease patients’ movement difficulties after the standard therapy levodopa wore off, a Phase 3 clinical trial showed. "Apomorphine, also known as APL-130277, works by mimicking dopamine’s activity in the brain. "Between
PDConscience
in
Cure Parkinson's
7 years ago
Morning dystonia
Does anyone have a solution for morning dystonia caused by levodopa. Someone suggested nepro patch can help. I have to wait to take Sinemet which although causes it also stops it. So I have to wait an,hour or two every morning with this awful till I can take first Sinemet. I was looking for non med solutions
Does anyone have a solution for morning dystonia caused by levodopa. Someone suggested nepro patch can help. I have to wait to take Sinemet which although causes it also stops it. So I have to wait an,hour or two every morning with this awful till I can take first Sinemet. I was looking for non med solutions
Connie18
in
Cure Parkinson's
7 years ago
Getting Mucuna from USA to UK
Has anyone in the UK ordered large quantities of 98% L-dopa, for example 1kg from the States? Did it get to the UK ok? Worried that bigger quantities might not make it through customs (not that there is any reason for this)... postage is free if you do get the larger sizes, so we'd like to do this.
Has anyone in the UK ordered large quantities of 98% L-dopa, for example 1kg from the States? Did it get to the UK ok? Worried that bigger quantities might not make it through customs (not that there is any reason for this)... postage is free if you do get the larger sizes, so we'd like to do this.
billyroca
in
Cure Parkinson's
7 years ago
PD & Mucuna
This past December I reluctantly succumbed to the inevitable
Carbidopa
levodopa
. 25 / 100 milligrams. In my quest to get in better shape to eat more healthy and fight this debilitating disease I came across someone with PD using a natural Bean called mucuna.
This past December I reluctantly succumbed to the inevitable
Carbidopa
levodopa
. 25 / 100 milligrams. In my quest to get in better shape to eat more healthy and fight this debilitating disease I came across someone with PD using a natural Bean called mucuna.
Stevenmast
in
Cure Parkinson's
7 years ago
Golden-nbm (new)
Can anyone help with information on taking sine met 50 mg 4 times daily and levodopa 15 mg at bed time. Husband has PD and is experiencing dizziness.
Can anyone help with information on taking sine met 50 mg 4 times daily and levodopa 15 mg at bed time. Husband has PD and is experiencing dizziness.
Golden-nbm
in
Cure Parkinson's
7 years ago
Personalized medicine in Parkinson's disease: Time to be precise.
open access. Personalized medicine in Parkinson's disease: Time to be precise. Mov Disord 2017 Aug;32(8):1147-1154. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575483/ The treatment of PD remains underpinned by levodopa and other dopamine replacement therapies (DRT). Although DRT and in particular
open access. Personalized medicine in Parkinson's disease: Time to be precise. Mov Disord 2017 Aug;32(8):1147-1154. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575483/ The treatment of PD remains underpinned by levodopa and other dopamine replacement therapies (DRT). Although DRT and in particular
aspergerian
in
Cure Parkinson's
7 years ago
My list of daily supplements
Now that I am finally recovering from the flu I am going to post what the daily regimen of supplements I am taking. Prior to listing the vitamins, minerals, amino acids....I am taking, I need to relate a little history. I have a degree in sculpture and was exposed to many chemicals including toluene
Now that I am finally recovering from the flu I am going to post what the daily regimen of supplements I am taking. Prior to listing the vitamins, minerals, amino acids....I am taking, I need to relate a little history. I have a degree in sculpture and was exposed to many chemicals including toluene
silvestrov
in
Cure Parkinson's
7 years ago
stopped C/L carbidopa levodopa er
After slow descent as of today I am not taking park med. Watching the symptoms for any change.
After slow descent as of today I am not taking park med. Watching the symptoms for any change.
Hidden
in
Cure Parkinson's
7 years ago
98% L-dopa
Hello UK-based healthunlockers! Our source of 98% L-dopa in the UK (Britishsupplements.net) is out of stock. Anyone got a difference supplier that comes via UK? Would be very very much appreciated, we're doing so well on L-dopa...
Hello UK-based healthunlockers! Our source of 98% L-dopa in the UK (Britishsupplements.net) is out of stock. Anyone got a difference supplier that comes via UK? Would be very very much appreciated, we're doing so well on L-dopa...
billyroca
in
Cure Parkinson's
7 years ago
Which medication to begin with?
I was diagnosed 18 months ago. I have a neurologist appt next week and feel that I now need to request meds. I was thinking of starting with Rasagaline then at later date L-DOPA. I prefer to have a say rather than simply accept. Can anyone offer advice based on experience?
I was diagnosed 18 months ago. I have a neurologist appt next week and feel that I now need to request meds. I was thinking of starting with Rasagaline then at later date L-DOPA. I prefer to have a say rather than simply accept. Can anyone offer advice based on experience?
gingerj
in
Cure Parkinson's
7 years ago
Parkinsons
I've been taking
carbidopa
/
levodopa
25-100MG tabs 2 tablets 4 times a day..it seems to be working ...but one side affect is my left leg & foot wants to move all the time..does anyone else have exccessive movement problems while taking this medication?
I've been taking
carbidopa
/
levodopa
25-100MG tabs 2 tablets 4 times a day..it seems to be working ...but one side affect is my left leg & foot wants to move all the time..does anyone else have exccessive movement problems while taking this medication?
darpay
in
Cure Parkinson's
7 years ago
Talk about Doom and Gloom!
I was just ferreting around Janice Hadlock Walton's PD Recovery site. Blimey, talk about damnation! The site declares that the organisation refuses to consider anybody as a 'patient' who's taken the slightest amount of Levadopa for more than 3 weeks as essentially this small ingestion buggers their
I was just ferreting around Janice Hadlock Walton's PD Recovery site. Blimey, talk about damnation! The site declares that the organisation refuses to consider anybody as a 'patient' who's taken the slightest amount of Levadopa for more than 3 weeks as essentially this small ingestion buggers their
jeeves19
in
Cure Parkinson's
7 years ago
A risk-free life is far from being a healthy life.
My cautionary note described taking very large amounts of vitamin B6 may be compromising both
carbidopa
and/or
levodopa
.
My cautionary note described taking very large amounts of vitamin B6 may be compromising both
carbidopa
and/or
levodopa
.
Hidden
in
Cure Parkinson's
7 years ago
Levodopa Medications and Vitamin B6
"
carbidopa
, which is combined with
levodopa
to reduce peripheral levodopa conversion and minimize peripheral dopamine side effects, binds irreversibly with PLP [another term for P5P].
"
carbidopa
, which is combined with
levodopa
to reduce peripheral levodopa conversion and minimize peripheral dopamine side effects, binds irreversibly with PLP [another term for P5P].
park_bear
in
Cure Parkinson's
7 years ago
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