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FDA Approves Tepmetko (tepotinib) for People with Metastatic Non-Small Cell Lung Cancer with MET-Exon 14 Mutation
On Feb. 15, 2024, the U.S. Food and Drug Administration (FDA) granted traditional approval of Tepmetko (tepotinib) for people living with metastatic non-small cell lung cancer (NSCLC) with a MET-Exon 14 mutation. Tepmetko (tepotinib) initially received accelerated approval in 2021 based on initial results
On Feb. 15, 2024, the U.S. Food and Drug Administration (FDA) granted traditional approval of Tepmetko (tepotinib) for people living with metastatic non-small cell lung cancer (NSCLC) with a MET-Exon 14 mutation. Tepmetko (tepotinib) initially received accelerated approval in 2021 based on initial results
Miranda_GO2
Partner
in
Lung Cancer Support
3 months ago
Optilume, scans, and tests
I found an old post on this "Balloon" based BPH treatment but no replies. I had a cystoscopy today as part of my decision making process for BPH treatment first or Gleason 7 (4+3) treatment first. My urologist gave me a brochure for a procedure he does called Optilume from a company called Laborie.
I found an old post on this "Balloon" based BPH treatment but no replies. I had a cystoscopy today as part of my decision making process for BPH treatment first or Gleason 7 (4+3) treatment first. My urologist gave me a brochure for a procedure he does called Optilume from a company called Laborie.
SherpaT
in
Prostate Cancer Network
3 months ago
4th line palliative systemic options?
Oncologist phone call today was not the news we were hoping for.PSA had been at 20 past 4 months and hubby was diagnosed as stable. Monthly PSA blood work is done and this month PSA jumped to 29. Oncologist is sending hubby for another Bone and CT scan. She has suggested either abiraterone, clinical
Oncologist phone call today was not the news we were hoping for.PSA had been at 20 past 4 months and hubby was diagnosed as stable. Monthly PSA blood work is done and this month PSA jumped to 29. Oncologist is sending hubby for another Bone and CT scan. She has suggested either abiraterone, clinical
Docker53
in
Advanced Prostate Cancer
3 months ago
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Clinical trials?
At the oncology appointment yesterday my husband was given what I believe is an amazing opportunity, he has the option of starting standard care ( immunotherapy pembrolizumab ) or participating in clinical trials where they will be also adding a second drug for a two pronged approach. Whilst I know
At the oncology appointment yesterday my husband was given what I believe is an amazing opportunity, he has the option of starting standard care ( immunotherapy pembrolizumab ) or participating in clinical trials where they will be also adding a second drug for a two pronged approach. Whilst I know
Flay75
in
The Roy Castle Lung Cancer Foundation
3 months ago
Colon Journey
I thought I’d share my journey leading up to this point and I hope to continue to update as things move along. I hate it when nobody updates. Timeline: 12 years ago: After my first daughter turned 1 I went to the bathroom with blood in stool. It was super bright red and a lot. Went to the doctor and
I thought I’d share my journey leading up to this point and I hope to continue to update as things move along. I hate it when nobody updates. Timeline: 12 years ago: After my first daughter turned 1 I went to the bathroom with blood in stool. It was super bright red and a lot. Went to the doctor and
Cleaneats
in
Colon Cancer Connected
3 months ago
Heart Disease and Abiraterone/Zytiga
Hello Warriors My husband had a calcium score done and it shows atherosclerotic disease. Dr wants to increase statin dose but the Zytiga side effects are giving him increase joint pain and discomfort.We will see his cardiologist in April. Have any of you seen any increase in heart related issues( calcification
Hello Warriors My husband had a calcium score done and it shows atherosclerotic disease. Dr wants to increase statin dose but the Zytiga side effects are giving him increase joint pain and discomfort.We will see his cardiologist in April. Have any of you seen any increase in heart related issues( calcification
Keeper70
in
Advanced Prostate Cancer
3 months ago
fast-rising PSA
I’m in the control group for the new Lutetium-177–PSMA-617 study re: use of Lutetium in the early stages of treatment for metastatic disease, pre-chemo. I was diagnosed 3/23 - high volume/high risk, and have been on Firmagon and Abiraterone plus pred. In Sept my PSA started to rise, with testosterone
I’m in the control group for the new Lutetium-177–PSMA-617 study re: use of Lutetium in the early stages of treatment for metastatic disease, pre-chemo. I was diagnosed 3/23 - high volume/high risk, and have been on Firmagon and Abiraterone plus pred. In Sept my PSA started to rise, with testosterone
NewGame
in
Advanced Prostate Cancer
3 months ago
Zytiga issue solved…
A big thank you to all who weighed in on whether I should take a lesser dose of abiraterone with food or just go without for a few days…….when I called my insurance company and got to talk to someone who gave a hoot it was discovered that a new pre-Auth was NOT needed…….10 or more phone calls later
A big thank you to all who weighed in on whether I should take a lesser dose of abiraterone with food or just go without for a few days…….when I called my insurance company and got to talk to someone who gave a hoot it was discovered that a new pre-Auth was NOT needed…….10 or more phone calls later
Tommyj2
in
Advanced Prostate Cancer
3 months ago
IS THIS A PATTERN???? Thoughts and helpful ideas to guide a path
Diagnosed Gleason 9 advanced, PSA 19, mets in pelvis(maybe more???)Had 6 x chemo ,5 X radio to prostate, ADT through out.PSA was down to 0.08 at one point.1 MARCH23 0.29 25 MAY23 0.08 NOV23 0.12 05 DEC23 0.25 12 FEB24 0.44 started feeling bouts of unreasonable tiredness, think maybe active cancer???
Diagnosed Gleason 9 advanced, PSA 19, mets in pelvis(maybe more???)Had 6 x chemo ,5 X radio to prostate, ADT through out.PSA was down to 0.08 at one point.1 MARCH23 0.29 25 MAY23 0.08 NOV23 0.12 05 DEC23 0.25 12 FEB24 0.44 started feeling bouts of unreasonable tiredness, think maybe active cancer???
Mrtroxely
in
Advanced Prostate Cancer
3 months ago
Is there seasonality to testosterone levels?
My ADT treatments (Lupron/Abiraterone/Prednisone) ended on May 02 2023 at which point both my PSA and Testosterone were flat lined. Here are the results of the four times I have been tested since the end of the ADT. * Aug 18 2023: PSA is 0.09, Testosterone is 3.3 nmol/l (95.2 ng/dL), Testosterone
My ADT treatments (Lupron/Abiraterone/Prednisone) ended on May 02 2023 at which point both my PSA and Testosterone were flat lined. Here are the results of the four times I have been tested since the end of the ADT. * Aug 18 2023: PSA is 0.09, Testosterone is 3.3 nmol/l (95.2 ng/dL), Testosterone
Mascouche
in
Advanced Prostate Cancer
3 months ago
treatment without surgery
hi, I’m new on here. First sorry to read and see what you are all going through, you are all very strong and brave. It’s my mum that has ovarian cancer stage 4, had 6 rounds of chemo then surgery - however the surgeon couldn’t operate as there was too much cancer to remove. My question is, has anyone
hi, I’m new on here. First sorry to read and see what you are all going through, you are all very strong and brave. It’s my mum that has ovarian cancer stage 4, had 6 rounds of chemo then surgery - however the surgeon couldn’t operate as there was too much cancer to remove. My question is, has anyone
Holsgram
in
My Ovacome
3 months ago
My treatment decisions
I want to thank this forum for men helping other men. I will list my experience in the hope it may help others. I especially want to thank Tall-Allen, whose advice and work on this forum is, to me, a truly meaningful endeavor, and when all is said and done, this is what life is about. I was diagnosed
I want to thank this forum for men helping other men. I will list my experience in the hope it may help others. I especially want to thank Tall-Allen, whose advice and work on this forum is, to me, a truly meaningful endeavor, and when all is said and done, this is what life is about. I was diagnosed
drzaius
in
Prostate Cancer Network
3 months ago
Keynote 365 Trial
Hey fellas, Seeing my MO tomorrow about enrolling in the Keynote 365 clinical trial with Keytruda in combination with another drug. Has anybody had any experience with Keytruda? Did it work for you? SE’s? I’m 17 years into this journey, castrate resistant, failed Xtandi, and recently failed Docetaxel
Hey fellas, Seeing my MO tomorrow about enrolling in the Keynote 365 clinical trial with Keytruda in combination with another drug. Has anybody had any experience with Keytruda? Did it work for you? SE’s? I’m 17 years into this journey, castrate resistant, failed Xtandi, and recently failed Docetaxel
deano58
in
Advanced Prostate Cancer
3 months ago
18F-flotufolastat PET alters treatment approach for nearly 90% of patients with recurrent prostate cancer
"18F-flotufolastat is approved by the FDA for use in patients with suspected prostate cancer metastasis who are potentially curable by definitive surgery or radiation, and patients with suspected prostate cancer recurrence based on elevated PSA levels." https://www.urologytimes.com/view/18f-flotufolastat-pet-alters-treatment-approach-for-nearly
"18F-flotufolastat is approved by the FDA for use in patients with suspected prostate cancer metastasis who are potentially curable by definitive surgery or radiation, and patients with suspected prostate cancer recurrence based on elevated PSA levels." https://www.urologytimes.com/view/18f-flotufolastat-pet-alters-treatment-approach-for-nearly
Maxone73
in
Advanced Prostate Cancer
3 months ago
Detection of a bacterial infection: Procalcitonin test
How to figure out if antibiotics should be considered ? There is a blood test measuring levels of Procalcitonin: if it is below 0.1 ng/mL, a bacterial infection is very unlikely, so antibiotics would be of no help. My question is: how reliable is this indicator, especially on the false negative side
How to figure out if antibiotics should be considered ? There is a blood test measuring levels of Procalcitonin: if it is below 0.1 ng/mL, a bacterial infection is very unlikely, so antibiotics would be of no help. My question is: how reliable is this indicator, especially on the false negative side
MikeOr
in
CLL Support
1 year ago
Diagnosed under 55
I’m looking specifically for men and partners of men who were diagnosed with de novo stage four prostate cancer at their initial diagnosis. The treatments are different and unfortunately so it the overall outlook. The younger men are diagnosed with PCa, the more aggressive the cancer tends to be.
I’m looking specifically for men and partners of men who were diagnosed with de novo stage four prostate cancer at their initial diagnosis. The treatments are different and unfortunately so it the overall outlook. The younger men are diagnosed with PCa, the more aggressive the cancer tends to be.
Vegasborn
in
Advanced Prostate Cancer
3 months ago
PSMA PET Looks Good But PSA Rising
Hello, I am hoping someone can help us understand what we might be missing prior to meeting with MO this week. My husband was diagnosed with metastatic prostate cancer with mets to pelvic lymph node and a few spots in bones in early January 2022 at 56 years old. He was successfully treated with Triplet
Hello, I am hoping someone can help us understand what we might be missing prior to meeting with MO this week. My husband was diagnosed with metastatic prostate cancer with mets to pelvic lymph node and a few spots in bones in early January 2022 at 56 years old. He was successfully treated with Triplet
FaithOverFear104
in
Advanced Prostate Cancer
3 months ago
Failed RP & SRT; Negative PSMA PET
Greetings. I had a radical prostatectomy that failed and then salvage radiation therapy that appears to have failed as well. A recent PSMA PET scan showed no signs of recurrent prostate cancer or metastases. By way of background: NOV 2010 - Dx at age 52; positive DRE, Gleason 3+3, PSA 5.0; prostate
Greetings. I had a radical prostatectomy that failed and then salvage radiation therapy that appears to have failed as well. A recent PSMA PET scan showed no signs of recurrent prostate cancer or metastases. By way of background: NOV 2010 - Dx at age 52; positive DRE, Gleason 3+3, PSA 5.0; prostate
dans_journey
in
Advanced Prostate Cancer
3 months ago
Virtual website advisory board for US Residents
*This is post was approved by GO2 for Lung Cancer Admin* A healthcare company is seeking patients who are 18 years and older who have been diagnosed with lung, ovarian, breast, endometrial or other solid tumor cancers to participate in a virtual Website Advisory Board in early 2024. The objective of
*This is post was approved by GO2 for Lung Cancer Admin* A healthcare company is seeking patients who are 18 years and older who have been diagnosed with lung, ovarian, breast, endometrial or other solid tumor cancers to participate in a virtual Website Advisory Board in early 2024. The objective of
Miranda_GO2
Partner
in
Lung Cancer Support
3 months ago
Any tips for recovery please
Had 2/3 of my right lung removed beginning of January for yet unknown lung cancer (Will see consultant for pathology this week) I coped alone with recovery but was do able. 2 Weeks ago after visiting A&E and a CT scan, I was found to have Pulmonary Embolisms in both lungs and Pneumonia in surgery lung
Had 2/3 of my right lung removed beginning of January for yet unknown lung cancer (Will see consultant for pathology this week) I coped alone with recovery but was do able. 2 Weeks ago after visiting A&E and a CT scan, I was found to have Pulmonary Embolisms in both lungs and Pneumonia in surgery lung
xinte60
in
The Roy Castle Lung Cancer Foundation
3 months ago
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