Experiences with

Bladder cancer

In vitro/in vivo but ready for clinical. I have found and tried to read the paper...what I understood is "great news!" but don't ask me to explain better than this: Prostate cancer treated with androgen deprivation therapy (ADT) can (will) develop into castration-resistant prostate cancer (CRPC), making

"This study reveals a previously unrecognized function of enzalutamide and AR by regulating PEX10 and suggests a new strategy of enzalutamide application in prostate cancer treatment." Not applied to any trial yet but an important finding! https://www.nature.com/articles/s41419-024-06937-7

While I'm very much into magnesium, and like cherry juice, I've not tried this - but the 'Sleepy Girl Mocktail' made the New York Times today: https://www.nytimes.com/2024/01/17/well/live/sleepy-girl-mocktail-cherry-magnesium.html More from the Cleveland Clinic last November: https://health.clevelandclinic.org

Hi. I was diagnosed with stage 1 breast cancer a year ago. I had surgery and radiotherapy and was put on Letrozole. I have had a few problems with the Letrozole, which saw me come off it for a while. I was put back on it and the Oncology Nurse told me to take Evening Primrose oil. it’s been 3 months

Hi everyone, I have a question for Sue and Jools as just left Doctors and wanted to check if the meds she's given me will be OK to take with RLS. I have had no choice but to go back on some tablets nd increase one, but have told her I did not want Statins again, she has given me Fenofibrate 200mg daily

The National Cancer Medicines Advisory Group (NCMAG) Programme have approached Ovacome as they are currently considering trametinib for patients with recurrent or progressive low grade serous ovarian carcinoma after at least one line of platinum-based chemotherapy for off-label use in NHSScotland.

Four years on and grateful for that. Enzalutamide stopped working earlier in the year. PSA doubling. Lesion in spine led to pathological fracture and some pressure on the spinal cord. Radiation to spine and pain relieved. Docetaxel started but discontinued due to severe allergic reaction. Nothing for

Dear all Hoping you are all as OK as possible. Having been originally diagnosed with breast cancer in Feb 2019, after which I had a lumpectomy and 3 lymph nodes removed(the latter were clear), I have been back and forth for many ops due to recurrences including a radical mastectomy after recurrence

Hey everyone...don't know if anyone has had this experience. I'm about 12 months into my PCa battle...been on Firmagon for most of it (including now). Started on Zytiga last year but had to stop due to elevated liver enzymes, so I switched to Casodex about two months ago, but PSA numbers started to

Finland, UK and Netherlands: a new theranostic based on actiniun 225 for metastatic prostate cancer https://www.theranostictrials.org/studies/cl74bp9il0233ajjfrlrlvs3d/NCT06052306

I’m currently on a Xtandi, Zometa and Lupron and have occasional foot numbness. Has anyone else experienced this?

61 with oligometastatic prostate cancer. PSA is currently down to 0.02 today after 6 months of Lupron and Erleada from PSA 150 in late Dec. '23. Started on Megestrol Acetate back in April, really reduced the side effects of ADT for me. My figure also looks about the as before treatment. I had a trans-rectal

It was exactly 1 year ago that I got my first elevated PSA test that started my prostate cancer experience (I don’t like to say “Journey”). Details in my comic. (http://burnscomic.com) After that, I had another PSA test (still elevated a month later), a pelvic MRI (showing pi-rads 5 areas), then a

PET Scan showed left hip radiated lesions SUV dropped from 30.2 to 3.5, 20.4 to 2.8, 7.5 to 2.5. Nothing in head, neck, organs. Now the bad news: Multiple new lesions in left hip with increased PET intensity from SUV 2.6 to 33.6 and left lower pelvic lymph node with SUV 16.1. PSA following 4/4/24 radiation

Hey, Looking for hope…aren’t we all? Husband had good results from Docetaxel, obliterating many bone mets and lowering PSA. Had CT/bone scan a couple months ago, showing suspicious areas. Dr. Ordered PSMA PET scans. Went over results with Dr. George today. He took my husband off Nubeqa due to

Hx ...De novo metastatic [over 20 bone mets] Gleason 9 diagnosed in 2014. Initial treatment Radical prostatectomy with LN dissection, 6 cycles of Docetaxel, and 3 months of Xtandi. Since that time intermittent treatment with Darolutamide full dose and then half dose. 7 different areas of bone mets tx

This cohort study indicates that more and earlier NGS testing may prolong the radiographic survival of patients with BRCA or other homologous recombination repair (HRR) alterations. Trends and Disparities in Next-Generation Sequencing in Metastatic Prostate and Urothelial Cancers JAMA Netw Open. 2024

I was wondering why they don’t just give chemo for Prostrate cancer irrespective of hormone sensitivity. Chemotherapy drugs destroy all rapidly dividing cells (even hair) so why would prostrate cancer cells be spared? I was trying to understand if ADT really kills PC cells or just makes them hibernate

In my prior (first) post, I shared about my 82 year old father’s condition. Thanks for all the helpful and thoughtful responses from this community. He has gone off Goserelin (ADT) injection and now just on bicalutamide pills. As his testosterone seems to have returned, he’s now having more energy

Hi I will be getting two treatments for HDR Brachytherapy in September at MD Anderson in AZ. Any tips with diet or exercising etc to heal and reduce the discomfort from it. You can see my diagnosis in my profile. Luckily for me prostate cancer has not spread. Currently on Orgovyx ADT . Have been