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Rising PSA with little shown on PSMA PET
Greetings all. I've been on this forum for years. I've only commented a handful of times, and never made a post. I prefer to usually just read from the sidelines. First of all, a bit about my path thus far. I was diagnosed in May 2010 (age 49) (PSA 4.7 and Gleason 7), had radical surgery in July 2010
Greetings all. I've been on this forum for years. I've only commented a handful of times, and never made a post. I prefer to usually just read from the sidelines. First of all, a bit about my path thus far. I was diagnosed in May 2010 (age 49) (PSA 4.7 and Gleason 7), had radical surgery in July 2010
velobard
in
Advanced Prostate Cancer
4 months ago
Introduction and asking for help interpreting latest scan results and thoughts on future treatment plan please.
Long time reader but first time posting.. I have just received my latest PSMA PET-CT scan results and would like some help interpreting the results and gain your thoughts about situation and treatment plan. My overall history: After slowly rising PSA scores to a relatively low peak of 6.1 at 59 years
Long time reader but first time posting.. I have just received my latest PSMA PET-CT scan results and would like some help interpreting the results and gain your thoughts about situation and treatment plan. My overall history: After slowly rising PSA scores to a relatively low peak of 6.1 at 59 years
APCFighter
in
Advanced Prostate Cancer
3 months ago
what is the risk from ALA?
What is this community’s take on ALA, as found in flaxseed oil? Is there risk for prostate cancer? If there is “risk”, is that solely an association with increased PSA? i.e. do significant amounts of flaxseed oil cause a change only in one’s baseline PSA? i.e. does it promote the [i]
production[
What is this community’s take on ALA, as found in flaxseed oil? Is there risk for prostate cancer? If there is “risk”, is that solely an association with increased PSA? i.e. do significant amounts of flaxseed oil cause a change only in one’s baseline PSA? i.e. does it promote the [i]
production[
lokibear0803
in
Advanced Prostate Cancer
4 months ago
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Caffeic acid phenethyl ester (CAPE) is an ingredient in bee propolis. See below for invitro and mice evidence for inhibition AR-V7 by CAPE
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Graham49
in
Advanced Prostate Cancer
6 months ago
PCA Prognosis?
Hi All! I am due for my 4rd Lupron treatment and follow-up next week. My bloodwork is done and my PSA is still <.01 for 9 months now. I have BRCA 1 and 2. When my Urologist gave me my initial diagnosis after my biopsies (Gleason 4+3=7 and 11 of 12 biopsies positive). nHe gave me a full report
Hi All! I am due for my 4rd Lupron treatment and follow-up next week. My bloodwork is done and my PSA is still <.01 for 9 months now. I have BRCA 1 and 2. When my Urologist gave me my initial diagnosis after my biopsies (Gleason 4+3=7 and 11 of 12 biopsies positive). nHe gave me a full report
Sagewiz
in
Advanced Prostate Cancer
4 months ago
Treatment awaited
Hi all I just completed my history incorrectly as a post. I have not posted before as I have been a silent member without any worrying ongoing elevations in PSA for about four years. I have keenly observed the posts of members and learned a good deal from them. This post is the follow up on my history
Hi all I just completed my history incorrectly as a post. I have not posted before as I have been a silent member without any worrying ongoing elevations in PSA for about four years. I have keenly observed the posts of members and learned a good deal from them. This post is the follow up on my history
Sisyphus
in
Advanced Prostate Cancer
3 months ago
My History to date
Diagnosed 09/2019 PSA 12.8 T2C Grade Group 5 - (4+5) Cores right posterior @15mm length, cores right mid and left posterior Grade Group 4 MRI showing Pi-Rads 5 lesion right side successfully targeted N0 Pet PSMA showing avidity right side of prostate and two avid lymph nodes common iliac and external
Diagnosed 09/2019 PSA 12.8 T2C Grade Group 5 - (4+5) Cores right posterior @15mm length, cores right mid and left posterior Grade Group 4 MRI showing Pi-Rads 5 lesion right side successfully targeted N0 Pet PSMA showing avidity right side of prostate and two avid lymph nodes common iliac and external
Sisyphus
in
Advanced Prostate Cancer
3 months ago
North not South
Psa at dx 139. Orgovyx and Nubeqa dropped it to 62.93 Started Docetaxil #1 Psa 23.91 #2 Psa 11.41 #3 Psa 7.15 #4 Psa 4.15 #5 Psa 2.38 #6 Psa 1.66 MO wanted to continue to 8. I agreed . There was a 6 week delay before #7. I took a Psa test right before 7 and it had dropped to 0.841 pleasantly
Psa at dx 139. Orgovyx and Nubeqa dropped it to 62.93 Started Docetaxil #1 Psa 23.91 #2 Psa 11.41 #3 Psa 7.15 #4 Psa 4.15 #5 Psa 2.38 #6 Psa 1.66 MO wanted to continue to 8. I agreed . There was a 6 week delay before #7. I took a Psa test right before 7 and it had dropped to 0.841 pleasantly
APK3
in
Advanced Prostate Cancer
3 months ago
Some good news to start the day: Complete Response in First Patient Ever Treated with 2 Doses of Cu-67 SAR-bisPSMA at 8GBq...6 months
I have already written about this, but then he approached the 6 months mark, so... "The patient remains with undetectable levels of Prostate Specific Antigen (PSA) for almost 6 months, following the administration of the second dose of 67Cu-SAR-bisPSMA. PSA is a marker used to assess clinical response
I have already written about this, but then he approached the 6 months mark, so... "The patient remains with undetectable levels of Prostate Specific Antigen (PSA) for almost 6 months, following the administration of the second dose of 67Cu-SAR-bisPSMA. PSA is a marker used to assess clinical response
Maxone73
in
Advanced Prostate Cancer
4 months ago
So the odds we all read about... are they true?
When my husband (age 52) was diagnosed with metastatic prostate cancer two and a half years ago, he was told the outlook was "grim." Everything we read told us once it moves to the bone (his has) then you're looking at months, not years, of life left. He had TEMPUS done, which was basically the oncologist
When my husband (age 52) was diagnosed with metastatic prostate cancer two and a half years ago, he was told the outlook was "grim." Everything we read told us once it moves to the bone (his has) then you're looking at months, not years, of life left. He had TEMPUS done, which was basically the oncologist
Anatalya
in
Advanced Prostate Cancer
4 months ago
Cancer Metabolic Disease and Focal Therapy advances are viable.
Focal ablation laser can be successful,for early stage PCa. 10-21 . GLEASON 3-4 , 5% PSA , 4.7. After treatment. No major erection issues long term, no need for tadalafil. PSA steadily declined. Recent MRI clear 3-24. and my ejaculate ducts were saved as well. PSA 0.4. So so far so good. Get an 2nd
Focal ablation laser can be successful,for early stage PCa. 10-21 . GLEASON 3-4 , 5% PSA , 4.7. After treatment. No major erection issues long term, no need for tadalafil. PSA steadily declined. Recent MRI clear 3-24. and my ejaculate ducts were saved as well. PSA 0.4. So so far so good. Get an 2nd
Mlsliver78
in
Prostate Cancer Network
3 months ago
PSA Nadir 6 Months After Primary RT Correlates With Prostate Cancer Outcomes — Or does it?, MedPage Today May 22, 2024
[i]This article from MedPage Today is reproduced in full along with the link to the full access editorial comment is also provided. However, it has numerous hyperlinks to the the research cited within. The link to the MedPage article provides those links. [/i] [i]* * *[/i]
PSA Nadir 6 Months After
[i]This article from MedPage Today is reproduced in full along with the link to the full access editorial comment is also provided. However, it has numerous hyperlinks to the the research cited within. The link to the MedPage article provides those links. [/i] [i]* * *[/i]
PSA Nadir 6 Months After
cujoe
in
Fight Prostate Cancer
4 months ago
Request for Input
Before I leave this wonderful group I'd like to pick your individual/collective brains. Since it's too late to help my husband, I'm looking for info that I can pass on to my son and 6 grandsons so they might better understand this awful cancer should they ever get it. I'm also providing a bit more info
Before I leave this wonderful group I'd like to pick your individual/collective brains. Since it's too late to help my husband, I'm looking for info that I can pass on to my son and 6 grandsons so they might better understand this awful cancer should they ever get it. I'm also providing a bit more info
Shamrock46
in
Advanced Prostate Cancer
4 months ago
Treatment update-is SBRT missing the lesions ?
PET scan 8/21 following PSA 54.5 showed numerous bone lesions. Zytiga, prednisone, Eligard knocked PSA to <.064 until 1/23 PET showed new small lesion in left hip. Radiation 35 Gray 5/5 completed 3/15/23 with PSA drop then bounce from 0.24 to 5.9 triggered another PET on 9/6/23 which showed a new metastasis
PET scan 8/21 following PSA 54.5 showed numerous bone lesions. Zytiga, prednisone, Eligard knocked PSA to <.064 until 1/23 PET showed new small lesion in left hip. Radiation 35 Gray 5/5 completed 3/15/23 with PSA drop then bounce from 0.24 to 5.9 triggered another PET on 9/6/23 which showed a new metastasis
alperk
in
Advanced Prostate Cancer
3 months ago
six years ago today!
It is early in the morning and I felt that I needed to tell somebody this info. It needs to be people that can really understand….. that’s where the people in this community come in, since you understand what we go through! Six years ago today I was diagnosed with stage 4, 4 plus 3 w over 25 metastases
It is early in the morning and I felt that I needed to tell somebody this info. It needs to be people that can really understand….. that’s where the people in this community come in, since you understand what we go through! Six years ago today I was diagnosed with stage 4, 4 plus 3 w over 25 metastases
Fitzbruce1
in
Advanced Prostate Cancer
3 months ago
Radiation Treatment Decision
Tall Allen or anyone else with helpful information, please advise. I am deciding between two large cancer centers for radiation treatment. My background: PSA was 45 in 2/24, now .04. Lupron/Xtandi taken since 2/24. Gleason score = 9 (4 +5). 75 years old. Cancer Center I - Radiation to prostate
Tall Allen or anyone else with helpful information, please advise. I am deciding between two large cancer centers for radiation treatment. My background: PSA was 45 in 2/24, now .04. Lupron/Xtandi taken since 2/24. Gleason score = 9 (4 +5). 75 years old. Cancer Center I - Radiation to prostate
buffman
in
Advanced Prostate Cancer
3 months ago
My Husband's update after Pluvicto.
Hi everyone, Happy 4th of July🙏🏻 👏🇺🇲Well here is the update. After my husband finished the Pluvicto treatment the psa never went down to 0 the lowest it got was .13 from 10.88 First 3 months without treatment, his psa began to rise. Right now his PSA it's at 4.69😢 He had a PSMA scan, that didn't
Hi everyone, Happy 4th of July🙏🏻 👏🇺🇲Well here is the update. After my husband finished the Pluvicto treatment the psa never went down to 0 the lowest it got was .13 from 10.88 First 3 months without treatment, his psa began to rise. Right now his PSA it's at 4.69😢 He had a PSMA scan, that didn't
Chiquis
in
Advanced Prostate Cancer
3 months ago
Eligard injection site
I’m changing from 3 month Lupron to 6 month Eligard. Lupron has always been injected in my hip and I’m wondering if Eligard can also use the same site. Thanks in advance for your comments.
I’m changing from 3 month Lupron to 6 month Eligard. Lupron has always been injected in my hip and I’m wondering if Eligard can also use the same site. Thanks in advance for your comments.
Lslal
in
Advanced Prostate Cancer
6 months ago
Using Enzalutamide, Darolutamide, Apalutamide only.
I've seen a number of posters here and there who say they use one of the "mides" listed above with no ADT like Lupron, Eligard, Firmagan, or Orgovyx, etc. If so, did you begin that regimen after being on first level ADT for a while along with the 'mide," or did you start on the "mide" alone at the start
I've seen a number of posters here and there who say they use one of the "mides" listed above with no ADT like Lupron, Eligard, Firmagan, or Orgovyx, etc. If so, did you begin that regimen after being on first level ADT for a while along with the 'mide," or did you start on the "mide" alone at the start
dhccpa
in
Prostate Cancer Network
6 months ago
No cancer found from TURP tissue ???
My husband had TURP a week ago because of years of issues with peeing . He was supposed to get this done last year but was diagnosed with stage 4 cancer , you may read my profile for his treatment and current PSA . The urologist said they would test all the tissue they take out . We were called by our
My husband had TURP a week ago because of years of issues with peeing . He was supposed to get this done last year but was diagnosed with stage 4 cancer , you may read my profile for his treatment and current PSA . The urologist said they would test all the tissue they take out . We were called by our
positive-thinking
in
Advanced Prostate Cancer
12 days ago
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