Some good news to start the day: Comp... - Advanced Prostate...

Advanced Prostate Cancer

21,371 members26,725 posts

Some good news to start the day: Complete Response in First Patient Ever Treated with 2 Doses of Cu-67 SAR-bisPSMA at 8GBq...6 months

Maxone73 profile image
9 Replies

I have already written about this, but then he approached the 6 months mark, so...

"The patient remains with undetectable levels of Prostate Specific Antigen (PSA) for almost 6 months, following the administration of the second dose of 67Cu-SAR-bisPSMA. PSA is a marker used to assess clinical response to treatment and an indicator of the recurrence of prostate cancer."

"Especially as we have now entered our first multi-dose cohort of the SECuRE trial, cohort 4, at a dose level of 12GBq, where we have already seen incredible benefits in patients that have failed so many lines of therapy. We hope to replicate this remarkable result in many patients and confirm the favourable safety profile of this agent."

must keep an eye on this, I am wondering about the results for the other patients dosed...

urotoday.com/recent-abstrac...

Written by
Maxone73 profile image
Maxone73
To view profiles and participate in discussions please or .
Read more about...
9 Replies
Ramp7 profile image
Ramp7

Looks promising, I shall keep an eye on this one. Thanks

God_Loves_Me profile image
God_Loves_Me

Are there any clincal trials in USA?

KocoPr profile image
KocoPr in reply to God_Loves_Me

I think in my other group cancer patient lab we have one warrior going into a trial run by xcancer out of omaha.

xcancer.com

Shams_Vjean profile image
Shams_Vjean in reply to God_Loves_Me

Omaha: - as per KocoPr above

NYC: - Scott Tagawa jcto.weill.cornell.edu/open...

Mayo-Rochester, MN: - Oliver Sator

St. Louis, MO: - Vikas Prasad

ClinicalTrials.gov: NCT04868604

I was considering this one, but opted for Pluvicto instead. Glad to hear the positive results are continuing.

Pmann profile image
Pmann

Really promising, it is always good to show that there are more ways coming to fight this dreadful disease.

leo2634 profile image
leo2634

Giving us real hope, My friends . Never give up Never surrender Leo

marlins1 profile image
marlins1

Where is the publication? What is the effective process? Just says it works.

Maxone73 profile image
Maxone73 in reply to marlins1

Type Cu-67 SAR-bisPSMA in google, but I think the first statistical data are due before the end of the year, they are at cohort 4

Shams_Vjean profile image
Shams_Vjean in reply to marlins1

Total enrollment of about 40 in the US for the current phase I/IIa trial is just getting underway at some clinics here. An Initial phase I trial was with 6 patients in Australia.

Developed by Clarity Pharmaceuticals, a Theranostics company out of Australia. The company’s website gives a brief overview of the mechanism.

youtu.be/QJz7dyxdEJo?si=CAQ...

You may also like...

Mortality Probability after first PSA rise vs non-castrate testosterone levels (low vs Normal)

Percent risk of Prostate Cancer-specific Mortality versus time following a first PSA failure, for...

copper chelation is not something from the past: phase 2 trial gives hope!

reductions in prostate-specific antigen (PSA) levels of greater than 35% from a single dose of...

Three months after RP to test PSA?

treatment for advanced prostate cancer within two months of surgery for better results. We...

Lucrin after orchidectomy

sharing. When my dad knew he got prostate cancer (Jun 2018), it was already bond metastasis...

PSA Recurrence - confused on next steps?

mean for my risk profile? • Prostate Surgery April 2016,(PSA was 9.6) - last PSA – 0.48 (01/18) -...