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1st Time posting. Need suggestions please.
My husband was diagnosed in Jul 2021 PSA 41 at the time, multiple mets in bones. n1b and m1b Gleason 4+3=7. I've been reading and trying to get as much info as possible from this website. Last Oct PSA shot up to 19. Xtandi started and he also gets the 3monthly Prostap injections. PSA went back down
My husband was diagnosed in Jul 2021 PSA 41 at the time, multiple mets in bones. n1b and m1b Gleason 4+3=7. I've been reading and trying to get as much info as possible from this website. Last Oct PSA shot up to 19. Xtandi started and he also gets the 3monthly Prostap injections. PSA went back down
Akita123
in
Advanced Prostate Cancer
9 months ago
Preparation for Chemo Second Time
Looking for information on tips to survive a second treatment of chemo. I will be starting 10 rounds of chemo soon. What should I do to help get through this again. I did 6 rounds at the beginning of diagnosis. I know about the ice gloves for the hands. Not sure they worked as I still have problems with
Looking for information on tips to survive a second treatment of chemo. I will be starting 10 rounds of chemo soon. What should I do to help get through this again. I did 6 rounds at the beginning of diagnosis. I know about the ice gloves for the hands. Not sure they worked as I still have problems with
Islandboy2021
in
Advanced Prostate Cancer
9 months ago
Now for something completely different
Monday, when you probably will see this post. Crack of dawn. I will be on my way to University Hospital London for a Radical Prostatectomy on Weds. Yes, I've had to learn a new lexicon of terms and medical knowledge. Whilst for the last few months I have been an observer of comments and post rather
Monday, when you probably will see this post. Crack of dawn. I will be on my way to University Hospital London for a Radical Prostatectomy on Weds. Yes, I've had to learn a new lexicon of terms and medical knowledge. Whilst for the last few months I have been an observer of comments and post rather
Tryfan
in
AF Association
9 months ago
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Do low PSA-producing cells still rely on testosterone to grow?
Am curious to know what the folks here know about this question. If higher PSA cells are driven to near extinction by ADT, and if only low-PSA producing cells survive, are the latter still dependent on testosterone for survival? If not, what do they depend on to grow?
Am curious to know what the folks here know about this question. If higher PSA cells are driven to near extinction by ADT, and if only low-PSA producing cells survive, are the latter still dependent on testosterone for survival? If not, what do they depend on to grow?
novatimo
in
Advanced Prostate Cancer
9 months ago
Low PSA and still progression?
How is this possible? Just curious, came by this article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873892/
How is this possible? Just curious, came by this article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873892/
Daddysgirl83
in
Advanced Prostate Cancer
9 months ago
EMBARK Study: ADT vs Enzalutamide +/- ADT
Results of the EMBARK study was published this week (10/19/23) in NEJM. It compared high risk BCR PCa treated in 3 groups: Lupron ADT alone. Enzalutamide plus ADT. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No ADT) was
Results of the EMBARK study was published this week (10/19/23) in NEJM. It compared high risk BCR PCa treated in 3 groups: Lupron ADT alone. Enzalutamide plus ADT. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No ADT) was
MateoBeach
in
Advanced Prostate Cancer
9 months ago
EMBARK Study: Enzalutamide +/- ADT
Results of the EMBARK study was published this week (10/19/23) in NEJM. It compared high risk BCR PCa treated in 3 groups: Lupron ADT alone. Enzalutamide plus ADT. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No ADT) was
Results of the EMBARK study was published this week (10/19/23) in NEJM. It compared high risk BCR PCa treated in 3 groups: Lupron ADT alone. Enzalutamide plus ADT. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No ADT) was
MateoBeach
in
Fight Prostate Cancer
9 months ago
T is going down.
I’m in my 10 mo. of holiday from Zytiga. My psa has risen from <0.04 to 0.90, my T value has risen from <7 to 24(LO) in 6 mo. Ago and than back down to 20 (LO) as of last week. My MO is concerned about the drop, should I? What is going on this. I feel great I feel strong.
I’m in my 10 mo. of holiday from Zytiga. My psa has risen from <0.04 to 0.90, my T value has risen from <7 to 24(LO) in 6 mo. Ago and than back down to 20 (LO) as of last week. My MO is concerned about the drop, should I? What is going on this. I feel great I feel strong.
6363lol
in
Advanced Prostate Cancer
9 months ago
Pluvicto
Recently had my third dose of Pluvicto, and the numbers are looking good. My PSA fell from about 90 to 35 after the first dose and to about 15 after the second. What they measure in the blood work has either been within the normal range or showing a positive trend. The scans show no new mets, a visible
Recently had my third dose of Pluvicto, and the numbers are looking good. My PSA fell from about 90 to 35 after the first dose and to about 15 after the second. What they measure in the blood work has either been within the normal range or showing a positive trend. The scans show no new mets, a visible
Leps
in
Advanced Prostate Cancer
9 months ago
Would I be on thin ice if I tried adaptive ADT this soon?
After 6 weeks on Lupron and 9 days on abiraterone, my PSA was .1, and my testosterone was <1. This is within the criteria being used to start people on adaptive in this MCSPC Moffitt study with Jingsong Yang - (he says I can just follow the protocol without being in the study)https://pubmed.ncbi.nlm.nih.gov
After 6 weeks on Lupron and 9 days on abiraterone, my PSA was .1, and my testosterone was <1. This is within the criteria being used to start people on adaptive in this MCSPC Moffitt study with Jingsong Yang - (he says I can just follow the protocol without being in the study)https://pubmed.ncbi.nlm.nih.gov
jackwfrench
in
Advanced Prostate Cancer
9 months ago
Sleep while taking Xtandi and Adt
Hello everyone, I am sure that this has been discussed on here before, I was unable to find any post to answer my question . I am taking Xtandi ( aprox 16 months) Lupron, I had chemo. My latest PSA was less then <0.01. It has been there for over a year now. ( See my profile for my journey.) My
Hello everyone, I am sure that this has been discussed on here before, I was unable to find any post to answer my question . I am taking Xtandi ( aprox 16 months) Lupron, I had chemo. My latest PSA was less then <0.01. It has been there for over a year now. ( See my profile for my journey.) My
JD-guy
in
Advanced Prostate Cancer
9 months ago
WORRIED ABOUT REOCCURRENCE???
Worried....
Stopped IMRT 1 year ago and stopped adt (4 mos) 9 months ago...
9/23/23 Blood Test PSA .1 --- PSA FREE undetectable and Testosterone was 98
3/4/24 Blood Test PSA .2 ----Psa Free Undetectable and Testosterone not in yet.
I am concerned about the increase
Worried....
Stopped IMRT 1 year ago and stopped adt (4 mos) 9 months ago...
9/23/23 Blood Test PSA .1 --- PSA FREE undetectable and Testosterone was 98
3/4/24 Blood Test PSA .2 ----Psa Free Undetectable and Testosterone not in yet.
I am concerned about the increase
JWS13
in
Advanced Prostate Cancer
4 months ago
Thunking of getting an orchiectomy insted od radiation
Has anyone had an orchiectomy and if so how were your side effects and how is your life after the Big O.I'm scheduled to start Full Pelvic Radiation in 6 weeks but fear the long term side effects. I asked if anyone here had FPR and if so what were their side effects and life like since then. Thanks for
Has anyone had an orchiectomy and if so how were your side effects and how is your life after the Big O.I'm scheduled to start Full Pelvic Radiation in 6 weeks but fear the long term side effects. I asked if anyone here had FPR and if so what were their side effects and life like since then. Thanks for
woppaginny
in
Advanced Prostate Cancer
9 months ago
Reporting results from Eclipse Trial
Prior to beginning trial last June I had just gone castrate resistant and PSA was at 3.3. A few weeks after the last of four injections PSA settled in at .25 so there was still something left. However PSA now has quickly shot up to .75 And since I stopped Orgovyx and Zytiga, Testosterone is going up
Prior to beginning trial last June I had just gone castrate resistant and PSA was at 3.3. A few weeks after the last of four injections PSA settled in at .25 so there was still something left. However PSA now has quickly shot up to .75 And since I stopped Orgovyx and Zytiga, Testosterone is going up
SViking
in
Advanced Prostate Cancer
9 months ago
Clinical Trial Dallas UT Southwestern
Will begin a Pfizer starting on Monday. I will post more later as it goes. We are adding a drug to Xtandi to treat solid tumors. I have been on and off Xtandi a few times. I am chemo naive. In the past had a very heavy tumor load and received 3 rounds of Lu-177 from Ishita Sen, Fortis health in Delhi
Will begin a Pfizer starting on Monday. I will post more later as it goes. We are adding a drug to Xtandi to treat solid tumors. I have been on and off Xtandi a few times. I am chemo naive. In the past had a very heavy tumor load and received 3 rounds of Lu-177 from Ishita Sen, Fortis health in Delhi
pilot52
in
Advanced Prostate Cancer
9 months ago
Has xtandi failed?
I had my lupron injection Tuesday and PSA checked. PSA 0.09, three months ago PSA was 0.06. I asked my doctor if xtandi has failed, he told me not necessarily. He told me once your PSA reached its lowest point it fluctuates up and down until it stabilized. I will have PSA checked again in 6 weeks
I had my lupron injection Tuesday and PSA checked. PSA 0.09, three months ago PSA was 0.06. I asked my doctor if xtandi has failed, he told me not necessarily. He told me once your PSA reached its lowest point it fluctuates up and down until it stabilized. I will have PSA checked again in 6 weeks
Echotango51
in
Advanced Prostate Cancer
9 months ago
Post-prostatectomy cancer status + treatment
Where we are in the story so far ... * 46 yo, diagnosed with prostate cancer April 2023 * MRIs were negative, ultimately diagnosed via biopsy * Gleason 3+4, last PSA 6.3, 6 cores with 3+3, 2 cores were 3+4 * PSMA PET Scan prior to surgery was clean * Had RALP procedure on September 26, 3 weeks ago
Where we are in the story so far ... * 46 yo, diagnosed with prostate cancer April 2023 * MRIs were negative, ultimately diagnosed via biopsy * Gleason 3+4, last PSA 6.3, 6 cores with 3+3, 2 cores were 3+4 * PSMA PET Scan prior to surgery was clean * Had RALP procedure on September 26, 3 weeks ago
MakeItRainbows
in
Prostate Cancer Network
9 months ago
Keytruda - year 4
So I’m pretty much closing the book on my 4th year on Keytruda (pembroluzimab). I’ve recently completely my 33rd Pembro infusion. Keytruda was my Hail Mary after running through most other SOC. My PSA was rising while on chemo the second time when I found out I had the markers that made me eligible
So I’m pretty much closing the book on my 4th year on Keytruda (pembroluzimab). I’ve recently completely my 33rd Pembro infusion. Keytruda was my Hail Mary after running through most other SOC. My PSA was rising while on chemo the second time when I found out I had the markers that made me eligible
Chugach
in
Advanced Prostate Cancer
9 months ago
Vacation from ADT
I searched but only came up with vacations at two years or so. I had a meeting with my MO today. He is conservative but suggested I could stop the meds. I was complaining of brain fog. He said to stop the Abi for about three weeks to see if there is any improvement and if not, stop Lupron. My story
I searched but only came up with vacations at two years or so. I had a meeting with my MO today. He is conservative but suggested I could stop the meds. I was complaining of brain fog. He said to stop the Abi for about three weeks to see if there is any improvement and if not, stop Lupron. My story
gsun
in
Advanced Prostate Cancer
9 months ago
He lived a wonderful life
My father passed away on Sunday, 10/15/2023, at the age of 91. We initially learned of his very high PSA level on 10/14/2021 (two years prior), with the diagnosis of Stage 4 metastatic prostate cancer soon thereafter. In addition to advanced prostate cancer, he had dementia that progressed significantly
My father passed away on Sunday, 10/15/2023, at the age of 91. We initially learned of his very high PSA level on 10/14/2021 (two years prior), with the diagnosis of Stage 4 metastatic prostate cancer soon thereafter. In addition to advanced prostate cancer, he had dementia that progressed significantly
Merlot1
in
Advanced Prostate Cancer
9 months ago
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