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PharmaTher Submits FDA Meeting Package to Discuss Phase 3 Program and Fast Track Designation for KETARX™ (Ketamine) in PD
https://www.benzinga.com/pressreleases/23/02/g30671310/pharmather-holdings-submits-fda-meeting-package-to-discuss-phase-3-program-and-fast-track-designat?utm_source=dlvr.it&utm_medium=twitter TORONTO, Feb. 01, 2023 (GLOBE NEWSWIRE) -- PharmaTher Holdings Ltd. (the "Company" or "PharmaTher") PHRRF
https://www.benzinga.com/pressreleases/23/02/g30671310/pharmather-holdings-submits-fda-meeting-package-to-discuss-phase-3-program-and-fast-track-designat?utm_source=dlvr.it&utm_medium=twitter TORONTO, Feb. 01, 2023 (GLOBE NEWSWIRE) -- PharmaTher Holdings Ltd. (the "Company" or "PharmaTher") PHRRF
Hidden
in
Cure Parkinson's
1 year ago
MANF Stack Rationale
….FOR INFORMATIONAL PURPOSES ONLY…… Unconventional neurotrophic factor MANF targets midbrain structures, including the Substantia Nigra, through endoplasmic reticulum mediated mechanisms. The midbrain, also called the mesencephalon, region of the brain serves important functions in motor activity
….FOR INFORMATIONAL PURPOSES ONLY…… Unconventional neurotrophic factor MANF targets midbrain structures, including the Substantia Nigra, through endoplasmic reticulum mediated mechanisms. The midbrain, also called the mesencephalon, region of the brain serves important functions in motor activity
House2
in
Cure Parkinson's
1 year ago
CLL Treatment concerns
Hello all, I have different options for my treatment, I have a lot of enlarged lymph nodes in my abdomen as per cat scan, it is causing me a lot of discomfort . I am 57 yrs old and my CLL is progressing. I need a treatment that can work getting my Lymph nodes back to normal size. I had a 6 months
Hello all, I have different options for my treatment, I have a lot of enlarged lymph nodes in my abdomen as per cat scan, it is causing me a lot of discomfort . I am 57 yrs old and my CLL is progressing. I need a treatment that can work getting my Lymph nodes back to normal size. I had a 6 months
CA28
in
CLL Support
1 year ago
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Lymphatic Dysfunction Found to Play Big Role in SLE Photosensitivity
Poor drainage in lymphatic system might explain processes leading to lupus flares by Lindsey Shapiro Reduced lymphatic drainage might explain why skin reactions to sunlight, or photosensitivity, may lead to systemic immune reactions and overall disease flareups in people with systemic lupus erythematosis
Poor drainage in lymphatic system might explain processes leading to lupus flares by Lindsey Shapiro Reduced lymphatic drainage might explain why skin reactions to sunlight, or photosensitivity, may lead to systemic immune reactions and overall disease flareups in people with systemic lupus erythematosis
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
1 year ago
So now I'm a bit scared.
I posted about deciding to do an ablation consult the other day, I have that scheduled for Dec 30th. Well that evening the 23rd I had a new arrhythmia show up. I sent it to Kardia clinician review, and they said it was ventricular tachycardia. The sort of rhythm that when sustained can lead to ventricular
I posted about deciding to do an ablation consult the other day, I have that scheduled for Dec 30th. Well that evening the 23rd I had a new arrhythmia show up. I sent it to Kardia clinician review, and they said it was ventricular tachycardia. The sort of rhythm that when sustained can lead to ventricular
ChasMartin
in
AF Association
2 years ago
📚 Research 101: What is a Clinical Trial
[u]
What is a clinical trial?
[/u] A clinical trial is a research study that determines whether new treatments are safe and effective for humans. Clinical trials are strictly controlled to ensure the safety of the people taking part. [u]
Who comes up with clinical trials?
[/u] Ideas for
[u]
What is a clinical trial?
[/u] A clinical trial is a research study that determines whether new treatments are safe and effective for humans. Clinical trials are strictly controlled to ensure the safety of the people taking part. [u]
Who comes up with clinical trials?
[/u] Ideas for
AnnaHU
HealthUnlocked
in
Research Opportunities
1 year ago
Ablation done - feeling fine (relatively)
(63 year old - history of congenital heart disease - coarctation of aorta correction in 1969 - stroke 3 years ago - diagnosed
atrial
(probably)
flutter
2 years ago - had 120+ heart rate continously for last 4 months) Had catheter ablation at Birmingham 2 days ago under Mr Marshall.
(63 year old - history of congenital heart disease - coarctation of aorta correction in 1969 - stroke 3 years ago - diagnosed
atrial
(probably)
flutter
2 years ago - had 120+ heart rate continously for last 4 months) Had catheter ablation at Birmingham 2 days ago under Mr Marshall.
mrhappydays
in
AF Association
2 years ago
Afib worse than before ablation
I had the most glorious day in 3 years on the 4th day after my first ablation, which the doc said went great. The first three days were tougher because I had a sort throat, fever, then a migraine. But on day 4 I felt incredible…until about 9:30pm when my watch told me I was in afib again. And then
I had the most glorious day in 3 years on the 4th day after my first ablation, which the doc said went great. The first three days were tougher because I had a sort throat, fever, then a migraine. But on day 4 I felt incredible…until about 9:30pm when my watch told me I was in afib again. And then
UnhappyAF
in
AF Association
2 years ago
”Aggressive” AF
Does anybody on here have experience or encouraging stories about Atrial Fibrillation especially the aggressive kind. I'm 43 and diagnosed with AF in March '21. I've had a cardioversion, 2 ablations in the upper chamber and 1 ablation in a lower chamber. The last ablation was in June then in July, I
Does anybody on here have experience or encouraging stories about Atrial Fibrillation especially the aggressive kind. I'm 43 and diagnosed with AF in March '21. I've had a cardioversion, 2 ablations in the upper chamber and 1 ablation in a lower chamber. The last ablation was in June then in July, I
BeeBee79
in
AF Association
2 years ago
Phase 1b trial shows reformulated Niclosamide has promise for CRPC
Niclosamide in prostate cancer: An inhibitor of AR-V7, a mitochondrial uncoupler, or more? Author links open overlay panelMinasSakellakisabShow moreOutlineShareCite https://doi.org/10.1016/j.ctarc.2023.100685 Get rights and contentUnder a Creative Commons licenseOpen accessHighlights •A recent phase
Niclosamide in prostate cancer: An inhibitor of AR-V7, a mitochondrial uncoupler, or more? Author links open overlay panelMinasSakellakisabShow moreOutlineShareCite https://doi.org/10.1016/j.ctarc.2023.100685 Get rights and contentUnder a Creative Commons licenseOpen accessHighlights •A recent phase
Graham49
in
Advanced Prostate Cancer
1 year ago
Community Guidelines
Community Name (“Research Opportunities”)
About This Community
The purpose of this online community is to stimulate dialogue, and encourage ongoing discussion on Research Opportunities and Research-related topics, as well as provide you with a better understanding of clinical trials
Community Name (“Research Opportunities”)
About This Community
The purpose of this online community is to stimulate dialogue, and encourage ongoing discussion on Research Opportunities and Research-related topics, as well as provide you with a better understanding of clinical trials
AnnaHU
HealthUnlocked
in
Research Opportunities
1 year ago
Small molecule ACK1 inhibitor (R)-9b - third generation AR receptor - clinical trial I in 2023
Technogenesys will start a trial in 2023, be prepared: Thus,, there is an acute need for next generation of inhibitor that can overcome Enzalutamide and Abiraterone resistance. We have identified (R)-9b as a `third generation' of AR-antagonist, which has ability to overcome Enzalutamide and abiraterone-resistant
Technogenesys will start a trial in 2023, be prepared: Thus,, there is an acute need for next generation of inhibitor that can overcome Enzalutamide and Abiraterone resistance. We have identified (R)-9b as a `third generation' of AR-antagonist, which has ability to overcome Enzalutamide and abiraterone-resistant
Hidden
in
Advanced Prostate Cancer
1 year ago
Any ideas/stories about treating PAC’s??
Had ablation in May of this year for lone AFib. Structurally normal heart. Had mild runs of PACs prior to the procedure that would come and go. Now going on 7 months after procedure and they are more bothersome than the AFib was. Last for hours and/or days on end. It’s really wearing me down. I’ve tried
Had ablation in May of this year for lone AFib. Structurally normal heart. Had mild runs of PACs prior to the procedure that would come and go. Now going on 7 months after procedure and they are more bothersome than the AFib was. Last for hours and/or days on end. It’s really wearing me down. I’ve tried
Golf1515
in
AF Association
2 years ago
atrial fibrillation and atrial flutter and hot weather
I presume this was
atrial
flutter
? I am aware of the medical interventions for Afib but does anyone know of any other proper research on natural interventions that folk have found helpful?
I presume this was
atrial
flutter
? I am aware of the medical interventions for Afib but does anyone know of any other proper research on natural interventions that folk have found helpful?
Robfromwales
in
British Heart Foundation
2 years ago
just started on levothyroxine
I have been taking levothyroxine for just over 2 months. My gp started me on a very low dose of 25mg and I’m due bloods in a month. After about 4 weeks it felt like my tiredness had improved and I was feeling more energetic but the last few weeks I feel back to square one again. I had a partial thyroidectomy
I have been taking levothyroxine for just over 2 months. My gp started me on a very low dose of 25mg and I’m due bloods in a month. After about 4 weeks it felt like my tiredness had improved and I was feeling more energetic but the last few weeks I feel back to square one again. I had a partial thyroidectomy
Amyob12
in
Thyroid UK
1 year ago
A-Flutter Ablation Success
How many have had an a-flutter ablation and it lasted? My doctor made it sound like its one and done for a long time to come but the more I read, the more it makes me think it's just temporary and a way of life to have to keep going in or then possibly have to get another one for Afib very soon after
How many have had an a-flutter ablation and it lasted? My doctor made it sound like its one and done for a long time to come but the more I read, the more it makes me think it's just temporary and a way of life to have to keep going in or then possibly have to get another one for Afib very soon after
Aflutter1
in
AF Association
2 years ago
New shooting pain in left breast
So today I have another strange new symptom - quick shooting pain from my left side across/through my left breast. Its happened 3 times today and each time its been about 6 quick pains then went away, all times I have been relaxed and at rest. I have done an ECG on my Apple Watch, checked my heart
So today I have another strange new symptom - quick shooting pain from my left side across/through my left breast. Its happened 3 times today and each time its been about 6 quick pains then went away, all times I have been relaxed and at rest. I have done an ECG on my Apple Watch, checked my heart
HappyDiamonds
in
PMRGCAuk
2 years ago
Cox maze: anyone had this procedure?
Hi all just booked for a private consult with cardiothoraticic surgeon in northwest, hopefully for Cox maze procedure for afib. Was in a+e for 14 hours yesterday on monitors...sent me home, still in AFib. Long story, but bit by bit I am finding out that treatment for my AFib is very limited due to other
Hi all just booked for a private consult with cardiothoraticic surgeon in northwest, hopefully for Cox maze procedure for afib. Was in a+e for 14 hours yesterday on monitors...sent me home, still in AFib. Long story, but bit by bit I am finding out that treatment for my AFib is very limited due to other
DizzyD
in
Atrial Fibrillation Support
2 years ago
I am back again sorry if I wrote this last night.
almost a month ago I had a cardioversion and it was amazing. I have been dealing with a heart rate in the 150s since the end of April. When I woke up from the CV it was 82. I actually had a smile as I awoke. I did not even know my heart rate was down yet so maybe it was the drugs lol but I felt happier
almost a month ago I had a cardioversion and it was amazing. I have been dealing with a heart rate in the 150s since the end of April. When I woke up from the CV it was 82. I actually had a smile as I awoke. I did not even know my heart rate was down yet so maybe it was the drugs lol but I felt happier
DawnTX
in
AF Association
2 years ago
Metoprolol
I have a CT angiogram tomorrow at 0830 and have been given two tablets of Metoprolol (50mg) to take 12 hrs and then 2hrs before the procedure. This is apparently to slow the heart down (to below 60bpm). I rang the hospital and told them that I already take Sotalol and my heart rate is generally slow
I have a CT angiogram tomorrow at 0830 and have been given two tablets of Metoprolol (50mg) to take 12 hrs and then 2hrs before the procedure. This is apparently to slow the heart down (to below 60bpm). I rang the hospital and told them that I already take Sotalol and my heart rate is generally slow
Samazeuilh2
in
AF Association
2 years ago
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