Experiences with

Ambroxol

I just googled for "ambroxol" and got a page for "Ambroxol AL 30 mg Tabletten zur Schleimlösung, 100 pcs.

Phase II trial of ambroxol as a disease modifying therapy for Parkinson’s disease dementia https://youtu.be/hpsa1gA6qyk

You can now order direct with a monthly subscription from anywhere in the world: https://findambroxol.com See brand above

I have not determined if this would apply to Ambroxol and Montelukast. Does anyone know? (Ambroxol and Montelukast are believed to protective as well. This can be elaborated upon in a different thread.)

https://jamanetwork.com/journals/jamaneurology/fullarticle/2758317

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469994/ Ambroxol is a mucoactive substance, so maybe these natural compounds in article are worth a try if you can’t get or don’t want to use ambroxol.

in mouth Taste disturbances https://www.medicoverhospitals.in/medicine/ambroxol#side-effects

And that has not improved so far, if anything it is worst, though given how badly it fluctuated before we cannot say with any certainty it is related to ambroxol, and insomnia was not a noted side effect in the ambroxol / Parkinsons safety study.

Why is Ambroxol not approved by the FDA when it is readily available in Europe in countries with higher safety standards? Does anyone know the history that lead to this? And does anyone have knowledge of whether this will be changing?

Am I reading the Ambroxol trial results correctly on page 32? They don't seem to be showing improvement over time. Some a little better, some a little worse? https://cdn.jamanetwork.com/ama/content_public/journal/neur/938436/noi190109supp2_prod.pdf?

I wonder if anyone is taking both Ambroxol and Exenatide?

And a new Phase 3 clinical trial is being set up for the respiratory drug known as , which has been shown to elevate levels of a Parkinson’s associated enzyme in patients.

Thread for first-hand experiences of Ambroxol usage here: https://healthunlocked.com/cure-parkinsons/posts/145844935/firsthand-ambroxol-experience

Then a few months ago he started on 2x30mg ambroxol x2 per day And 1 tsp Ceylon cinnamon And 500mg of rhodiola rosea He has swapped fish oil to one with high epa 1200: DHA 300 ratio. And added hemp oil 2000mg per day, liposomal vitamin c, citrus bioflavonoids, krill oil.

The rhodiola experiment is being run at the same time as the cinnamon x 2 tsp per day and ambroxol 60mg x 2 per day.

- α-synuclein, yes the very same neuronal protein thought to be the culprit behind PD, and that Ambroxol has been found to reduce (I prefer dispose of) by increasing GCase enzyme activity. So can we extrapolate that Ambroxol may be able to help people with Melanoma too?

Exanatide or Ambroxol might be helpful. Fecal transplants are looking like a possible source of some help. Improvements in DBS are being trialed at UCSF. I hope for gene therapy but I think that is likely more like 20 + years out. Meds to reduce dyskinesia are being trialed according to MJFF.

Please can ONLY PwP taking Ambroxol post their experience here please? (And no one hijack the thread/send it off-topic!!) Have trawled Google and found three persons’ experiences (Jellywoman, dhp and one other on here) Thanks!

The 2nd link below on a current trial underway in Ambroxol for PD dementia includes a pretty powerful statement about Ambroxol: "This (Ambroxol) strategy could stop or reverse the underlying pathology of PD; it might allow patients to get better."

Is there a current trial taking place for Ambroxol?