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13 public posts

Cough syrup drug being trialed as Parkinson’s treatment

Ambroxol also appears to reduce Parkinson’s-related alpha-synuclein levels.
Ambroxol also appears to reduce Parkinson’s-related alpha-synuclein levels.
JayPwP
in Parkinson's Movement

Ambroxol : Can we please hear from all those who are taking Ambroxol?

There are other threads addressing Ambroxol but from what I’ve seen, only one PWP has shared their personal experience.
There are other threads addressing Ambroxol but from what I’ve seen, only one PWP has shared their personal experience.
cclemonade
in Parkinson's Movement

Has any tried Ambroxol?

There are trials continuing with Ambroxol, wondered if any of you have tried it and at what dose and if it had any effect? I know in the trial they are eventually having up to 1050 mg per day. Thanks!
There are trials continuing with Ambroxol, wondered if any of you have tried it and at what dose and if it had any effect? I know in the trial they are eventually having up to 1050 mg per day. Thanks!
Alex2004
in Parkinson's Movement
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Ambroxol for PD

Hi all This is a link to my vlog about the recent clinical trial of ambroxol for PD. https://youtu.be/zbqcdxcNWCc Cheers, Ian
Hi all This is a link to my vlog about the recent clinical trial of ambroxol for PD. https://youtu.be/zbqcdxcNWCc Cheers, Ian
Ianfrizell
in Parkinson's Movement

Ambroxol in Parkinson's: Results of Phase ll Trial Published

There was a 6.8 reduction (indicating improvement) in the clinician-based rating scale measurement and these effects were seen in those participants with and without GBA mutations https://www.cureparkinsons.org.uk/news/ambroxol-phase-ll-results-published?
There was a 6.8 reduction (indicating improvement) in the clinician-based rating scale measurement and these effects were seen in those participants with and without GBA mutations https://www.cureparkinsons.org.uk/news/ambroxol-phase-ll-results-published?
iqbaliqbal
in Parkinson's Movement

Ambroxol Phase 2 results

https://www.cureparkinsons.org.uk/news/ambroxol-phase-ll-results-published https://jamanetwork.com/journals/jamaneurology/fullarticle/2758317 Open study with no placebo but interesting results. There is a larger scale placebo study currently taking places in France.
https://www.cureparkinsons.org.uk/news/ambroxol-phase-ll-results-published https://jamanetwork.com/journals/jamaneurology/fullarticle/2758317 Open study with no placebo but interesting results. There is a larger scale placebo study currently taking places in France.
Parkinsonjisung
in Parkinson's Movement

COUGH SYRUP SHOWS PROMISING RESULT FOR PD TREATMENT.

Hi Friends, follow the link: https://www.parkinson.org/blog/science-news/Drug-Ambroxol.
Hi Friends, follow the link: https://www.parkinson.org/blog/science-news/Drug-Ambroxol.
OREOLU
in Parkinson's Movement

PD: Search for the Holy Grail

breakthroughs for the next 2 decades: "New therapeutic targets following the discovery of genetic risk factors, such as autosomal dominant mutations in the LRRK2 gene; and the enzyme glucocerebrosidase (GCase), which is reduced in patients with mutations in the GBA gene - including treatment with Ambroxol
breakthroughs for the next 2 decades: "New therapeutic targets following the discovery of genetic risk factors, such as autosomal dominant mutations in the LRRK2 gene; and the enzyme glucocerebrosidase (GCase), which is reduced in patients with mutations in the GBA gene - including treatment with Ambroxol
PDConscience
in Parkinson's Movement

experts review current research

several promising developments, including: New therapeutic targets following the discovery of genetic risk factors, such as autosomal dominant mutations in the LRRK2 gene; and the enzyme glucocerebrosidase (GCase), which is reduced in patients with mutations in the GBA gene – including treatment with Ambroxol
several promising developments, including: New therapeutic targets following the discovery of genetic risk factors, such as autosomal dominant mutations in the LRRK2 gene; and the enzyme glucocerebrosidase (GCase), which is reduced in patients with mutations in the GBA gene – including treatment with Ambroxol
melodie
in Parkinson's Movement

REVIEW ARTICLE: Drug Repurposing in Parkinson's Disease (31 July 2018)

Drugs covered in this review article: Ambroxol, Isradipine, Inosine, UDCA, Deferiprone, Exenatide, Nilotinib, Simvastatin. https://link.springer.com/epdf/10.1007/s40263-018-0548-y?
Drugs covered in this review article: Ambroxol, Isradipine, Inosine, UDCA, Deferiprone, Exenatide, Nilotinib, Simvastatin. https://link.springer.com/epdf/10.1007/s40263-018-0548-y?
jeffreyn
in Parkinson's Movement

Ambroxol experience?

Is anybody taking Ambroxol and if so is there any symptomatic improvement? I understand Ambroxol is available as over-the-counter medication in Europe. There are clinical trials going on and some clinics in Israel use it in treating Parkinson's.
Is anybody taking Ambroxol and if so is there any symptomatic improvement? I understand Ambroxol is available as over-the-counter medication in Europe. There are clinical trials going on and some clinics in Israel use it in treating Parkinson's.
felixned
in Parkinson's Movement

Is anyone taking Ambroxol? Please share

https://scienceofparkinsons.com/2017/04/16/an-ambroxol-update-active-in-the-brain/
https://scienceofparkinsons.com/2017/04/16/an-ambroxol-update-active-in-the-brain/
p-oui
in Parkinson's Movement

Importance of publishing results of Clinical Trials

AAV2-hAADC Ambroxol AZD3241 BIIB054 CDNF 18 Exenatide (Diabetes Drug) Fucoidan GM608 Inosine Isradipine LDN (Low Dose Naltrexone) LRRK2 Mannitol MSDC-0160 (Diabetes Treatment) NAC Neurturin Nilotinib Nicotine NPT200-11 NRF2 Opicaone OXB-102 PRX002 Ursodiol Uridine Vatiquinone
AAV2-hAADC Ambroxol AZD3241 BIIB054 CDNF 18 Exenatide (Diabetes Drug) Fucoidan GM608 Inosine Isradipine LDN (Low Dose Naltrexone) LRRK2 Mannitol MSDC-0160 (Diabetes Treatment) NAC Neurturin Nilotinib Nicotine NPT200-11 NRF2 Opicaone OXB-102 PRX002 Ursodiol Uridine Vatiquinone
FMundo
in Understanding Clinical Trials
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