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Alanine transaminase test (ALT)
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Darolutamide (Nubeqa) Vs Enzalutamide ( Xtandi)
Are there any studies comparing efficacy and side effect profile of darolutamide Vs enzalutamide when given together with first generation ADT ? I read that darolutamide does not cross blood brain barrier so may have lesser side effects ?
Are there any studies comparing efficacy and side effect profile of darolutamide Vs enzalutamide when given together with first generation ADT ? I read that darolutamide does not cross blood brain barrier so may have lesser side effects ?
Tinkudi
in
Advanced Prostate Cancer
1 month ago
Unusual case
Short summary. 79 years old. Surgery 12 years ago on G4+3. Recurrence 3 years later. IMRT and second recurrence 3 years later. No ADT. PSADT 1.5 years and now it's 2.3. Two PSMA scans. First showed nothing. Second showed ill defined area in prostate bed that might be positive. Never had ADT.
Short summary. 79 years old. Surgery 12 years ago on G4+3. Recurrence 3 years later. IMRT and second recurrence 3 years later. No ADT. PSADT 1.5 years and now it's 2.3. Two PSMA scans. First showed nothing. Second showed ill defined area in prostate bed that might be positive. Never had ADT.
npac
in
Advanced Prostate Cancer
1 month ago
PD and Prostate Cancer
...that is, there is never an end to the worst. I will soon have to undergo radiotherapy for prostate cancer. I am currently undergoing hormone therapy. I am looking for similar experiences and above all advice on how to manage this new situation in cohabitation with PD. Thank you very much.
...that is, there is never an end to the worst. I will soon have to undergo radiotherapy for prostate cancer. I am currently undergoing hormone therapy. I am looking for similar experiences and above all advice on how to manage this new situation in cohabitation with PD. Thank you very much.
Fed1000
in
Cure Parkinson's
1 month ago
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Treatment awaited
Hi all I just completed my history incorrectly as a post. I have not posted before as I have been a silent member without any worrying ongoing elevations in PSA for about four years. I have keenly observed the posts of members and learned a good deal from them. This post is the follow up on my history
Hi all I just completed my history incorrectly as a post. I have not posted before as I have been a silent member without any worrying ongoing elevations in PSA for about four years. I have keenly observed the posts of members and learned a good deal from them. This post is the follow up on my history
Sisyphus
in
Advanced Prostate Cancer
1 month ago
My History to date
Diagnosed 09/2019 PSA 12.8 T2C Grade Group 5 - (4+5) Cores right posterior @15mm length, cores right mid and left posterior Grade Group 4 MRI showing Pi-Rads 5 lesion right side successfully targeted N0 Pet PSMA showing avidity right side of prostate and two avid lymph nodes common iliac and external
Diagnosed 09/2019 PSA 12.8 T2C Grade Group 5 - (4+5) Cores right posterior @15mm length, cores right mid and left posterior Grade Group 4 MRI showing Pi-Rads 5 lesion right side successfully targeted N0 Pet PSMA showing avidity right side of prostate and two avid lymph nodes common iliac and external
Sisyphus
in
Advanced Prostate Cancer
1 month ago
Gleason 6 Treatment options .
Has anyone experienced Monotherapy - LDR Brachytherapy , without , EBRT or ADT . for Grade1 ( Gleason Score 3+3=6 Prostate Cancer ? OR LDR With EBRT Only ?
Has anyone experienced Monotherapy - LDR Brachytherapy , without , EBRT or ADT . for Grade1 ( Gleason Score 3+3=6 Prostate Cancer ? OR LDR With EBRT Only ?
Conlig1940
in
Advanced Prostate Cancer
1 month ago
Please share your experiences and thoughts.
My last psma scan results are below. Please share your thoughts and experiences regarding my psma results. Is this a bad report or reasonably good?. My psa is undetectable. I am on ADT vacation now for the last 7 months. Should I start ADT now or wait untill psa is detectable? 1. SPLEEN: No new
My last psma scan results are below. Please share your thoughts and experiences regarding my psma results. Is this a bad report or reasonably good?. My psa is undetectable. I am on ADT vacation now for the last 7 months. Should I start ADT now or wait untill psa is detectable? 1. SPLEEN: No new
Ahk1
in
Advanced Prostate Cancer
1 month ago
Update on Treatment
In June 2023, a routine PSA test value turned out to be 4.6, did an MRI; Diagnosed with Prostate Cancer, Gleason Score 7 (3+4), biopsy said one core. (Details in my profile). Opted for Active Surveillance. But in Oct 2023, PSA level went to 6.1 and in Jan 2024 PSA went to 9.2 In March 2024, did another
In June 2023, a routine PSA test value turned out to be 4.6, did an MRI; Diagnosed with Prostate Cancer, Gleason Score 7 (3+4), biopsy said one core. (Details in my profile). Opted for Active Surveillance. But in Oct 2023, PSA level went to 6.1 and in Jan 2024 PSA went to 9.2 In March 2024, did another
Sushupthi
in
Advanced Prostate Cancer
1 month ago
advice please!
Hello. I was diagnosed about a year ago with stage 4 prostate cancer. I was on hormone therapy but that is no longer surprising the cancer. It is in my bones, currently spreading in my pelvic bone and lumbar. I hope to start chemotherapy in the next month. But with my current health I don’t know
Hello. I was diagnosed about a year ago with stage 4 prostate cancer. I was on hormone therapy but that is no longer surprising the cancer. It is in my bones, currently spreading in my pelvic bone and lumbar. I hope to start chemotherapy in the next month. But with my current health I don’t know
BonnieKlyde
in
Advanced Prostate Cancer
1 month ago
ADT and creativity
I am a composer. Since I had ADT (Eligard - last shot in early April) I have experienced the conventional side effects - hot flashes, larger breasts, shrunken penis, no libido, tiredness. I am hoping those diminish over time. My question is to those who are occupational "creatives" - artists, writers
I am a composer. Since I had ADT (Eligard - last shot in early April) I have experienced the conventional side effects - hot flashes, larger breasts, shrunken penis, no libido, tiredness. I am hoping those diminish over time. My question is to those who are occupational "creatives" - artists, writers
Eadgbe
in
Prostate Cancer Network
1 month ago
Looking for any Info for Recent PC Diagnosis
I’m a 62 year old, recently diagnosed with advanced prostate cancer. I’ve been on hormone therapy for 2 weeks and see my oncologist in a week. My PC seems to be aggressive and my PSA is off the charts 885! I would love any positive info I can get.
I’m a 62 year old, recently diagnosed with advanced prostate cancer. I’ve been on hormone therapy for 2 weeks and see my oncologist in a week. My PC seems to be aggressive and my PSA is off the charts 885! I would love any positive info I can get.
Iber
in
Advanced Prostate Cancer
1 month ago
six years ago today!
It is early in the morning and I felt that I needed to tell somebody this info. It needs to be people that can really understand….. that’s where the people in this community come in, since you understand what we go through! Six years ago today I was diagnosed with stage 4, 4 plus 3 w over 25 metastases
It is early in the morning and I felt that I needed to tell somebody this info. It needs to be people that can really understand….. that’s where the people in this community come in, since you understand what we go through! Six years ago today I was diagnosed with stage 4, 4 plus 3 w over 25 metastases
Fitzbruce1
in
Advanced Prostate Cancer
1 month ago
How I Cope With ADT
Episode 10 of My Journey With Prostate Cancer playlist. This episode is less satirical, just hoping somebody finds something in it useful. https://youtu.be/HMxB8DBM1X4?si=Mx81mBr1x_6ClBLn
Episode 10 of My Journey With Prostate Cancer playlist. This episode is less satirical, just hoping somebody finds something in it useful. https://youtu.be/HMxB8DBM1X4?si=Mx81mBr1x_6ClBLn
Caldonia
in
Advanced Prostate Cancer
1 month ago
Non-adt prostate cancer treatment
I was recently diagnosed with stage 3, non-metastatic prostate cancer: Gleason score 7 (half 3/4, half 4/3). I have had both hips previously replaced. I recently had three stents inputted. I don't like the feel and taste of androgen replacement therapy. Does anyone know of a legitimate entity
I was recently diagnosed with stage 3, non-metastatic prostate cancer: Gleason score 7 (half 3/4, half 4/3). I have had both hips previously replaced. I recently had three stents inputted. I don't like the feel and taste of androgen replacement therapy. Does anyone know of a legitimate entity
Cletom
in
Prostate Cancer Network
1 month ago
ADT questions
I received 3 month Eligard shot April 11, pre 28 IMRT, completed May 31. Second 3 month scheduled On July 16. I have some daytime urgency after radiation and pee 3-5 times per night. On 2 tamsulosin. I have had no other symptoms, no hot flashes and no fatigue since radiation. This morning I woke with
I received 3 month Eligard shot April 11, pre 28 IMRT, completed May 31. Second 3 month scheduled On July 16. I have some daytime urgency after radiation and pee 3-5 times per night. On 2 tamsulosin. I have had no other symptoms, no hot flashes and no fatigue since radiation. This morning I woke with
SherpaT
in
Prostate Cancer Network
1 month ago
Recent Diagnosis
Good evening everyone, I’m new to this forum. My somewhat depressing story is in my bio. Anyone had a similar diagnosis that’s further down the line and can offer any encouragement? One tiny bit of more positive news is that since starting the hormone treatment my back pain (which was the only real symptom
Good evening everyone, I’m new to this forum. My somewhat depressing story is in my bio. Anyone had a similar diagnosis that’s further down the line and can offer any encouragement? One tiny bit of more positive news is that since starting the hormone treatment my back pain (which was the only real symptom
Yellowtail33
in
Advanced Prostate Cancer
2 months ago
To scan or not to scan, that is the question.
I've had my two years on ADT, and now I'm 6 months into my "vacation" (iADT) PSA has hit 2.0, and the plan is to restart ADT when it hits 5.0. Assuming there are no complications, I'm okay with that plan. Also assuming there are no complications, my MO says we won't be doing a PSMA scan, or any radiation
I've had my two years on ADT, and now I'm 6 months into my "vacation" (iADT) PSA has hit 2.0, and the plan is to restart ADT when it hits 5.0. Assuming there are no complications, I'm okay with that plan. Also assuming there are no complications, my MO says we won't be doing a PSMA scan, or any radiation
Lewellen
in
Advanced Prostate Cancer
2 months ago
What does ‘neuroendocrine differentiation' mean in metastatic prostate cancer?
My 71 year old dad has been diagnosed with metastatic prostate cancer with neuroendocrine differentiation - he had absolutely zero symptoms until a lymph node on his neck swelled up. It’s metastasised to his lower spine and sternum too. He’s just had his oncology appointment today and they’re going to
My 71 year old dad has been diagnosed with metastatic prostate cancer with neuroendocrine differentiation - he had absolutely zero symptoms until a lymph node on his neck swelled up. It’s metastasised to his lower spine and sternum too. He’s just had his oncology appointment today and they’re going to
NikkiJayne
in
Advanced Prostate Cancer
2 months ago
Abiraterone weaning
When the time comes to stop ADT and abiraterone, for good reasons. Does anyone here have info on abiraterone weaning planning? Including prednisone weaning? TIA
When the time comes to stop ADT and abiraterone, for good reasons. Does anyone here have info on abiraterone weaning planning? Including prednisone weaning? TIA
Derf4223
in
Advanced Prostate Cancer
2 months ago
Dealing with the Anxiety and Depression From Cancer
There recently was an excellent discussion about the how to overcome anxiety and depression caused by this cancer. It seemed to focus on the use of medicines and some herbal solutions. While I have no issue with that approach I was going to attach my comments to that thread and had second thoughts for
There recently was an excellent discussion about the how to overcome anxiety and depression caused by this cancer. It seemed to focus on the use of medicines and some herbal solutions. While I have no issue with that approach I was going to attach my comments to that thread and had second thoughts for
Mgtd
in
Advanced Prostate Cancer
2 months ago
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