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Experiences with
Alanine transaminase test (ALT)
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Genetic background strongly influences the impact of carrying the Thr92Ala-DIO2 polymorphism in the male mouse
Are you male? Are you a mouse? Do you carry the Thr92Ala-DIO2 allele? Can you wait for the publication of this paper? Can you wait for the human version of this trial? And do you consider it necessary to wait for the eventual publication of the human trial before considering T3? It is undoubtedly
Are you male? Are you a mouse? Do you carry the Thr92Ala-DIO2 allele? Can you wait for the publication of this paper? Can you wait for the human version of this trial? And do you consider it necessary to wait for the eventual publication of the human trial before considering T3? It is undoubtedly
helvella
Thyroid UK
in
Thyroid UK
1 month ago
If you take a small dose of T3 (6mcg) does this slowly build up in your system or will it get used quickly every day?
I’m taking 6.25mcg of T3 for a week now I just wondered if this will build up in your system similar to T4? I know T4 is the storage hormone so that builds up slowly. I didn’t know whether the 6mcg will build up aswell as I was thinking of adding a little more but I don’t want to add more if it’s still
I’m taking 6.25mcg of T3 for a week now I just wondered if this will build up in your system similar to T4? I know T4 is the storage hormone so that builds up slowly. I didn’t know whether the 6mcg will build up aswell as I was thinking of adding a little more but I don’t want to add more if it’s still
ockerdoc
in
Thyroid UK
1 month ago
half life T3 in NDT
I've read over a period of time that T3 has half-life of anywhere from 2-2.5 days. I have, always, assumed (bad thing!) that was for synthetic T3. Anyone know, if that time-frame is applicable to dessicated T3? My FT3 shot up from 2.7 in late Feb. to 3.85 2 weeks ago. I had increased dose from97.5
I've read over a period of time that T3 has half-life of anywhere from 2-2.5 days. I have, always, assumed (bad thing!) that was for synthetic T3. Anyone know, if that time-frame is applicable to dessicated T3? My FT3 shot up from 2.7 in late Feb. to 3.85 2 weeks ago. I had increased dose from97.5
terebol
in
Thyroid UK
1 month ago
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Sudden crash back into fatigue.
After seeing my Endo last week, my T3 was kept the same (5mcg twice a day) and my t4 was put back up to 75. Usually it takes weeks before any difference shows doesn’t it? It wouldn’t be any difference in this case? The day after I started back on the higher dose I felt exhausted, insomnia and poor sleep
After seeing my Endo last week, my T3 was kept the same (5mcg twice a day) and my t4 was put back up to 75. Usually it takes weeks before any difference shows doesn’t it? It wouldn’t be any difference in this case? The day after I started back on the higher dose I felt exhausted, insomnia and poor sleep
Loopnova
in
Thyroid UK
1 month ago
reverse t3 testing.
I’m on a journey with t3 so far taking has not affected serum t3 levels and I have read that reverse t3 can block active t3. Has anyone here tested for this and did you find it useful? I understand it is a somewhat controversial test in the medical world Thanks!
I’m on a journey with t3 so far taking has not affected serum t3 levels and I have read that reverse t3 can block active t3. Has anyone here tested for this and did you find it useful? I understand it is a somewhat controversial test in the medical world Thanks!
Mag999
in
Thyroid UK
1 month ago
help needing t4
I wonder if anyone could help me I need to buy a top up of t4 without a prescription if someone could be as helpful as to give me an email address thankyou
I wonder if anyone could help me I need to buy a top up of t4 without a prescription if someone could be as helpful as to give me an email address thankyou
Kowbie
in
Thyroid UK
1 month ago
PSA Gone Up
I had RP in January of 2023, started ADT in May of 2023 and went through 38 session of SRT between July and August. In am currently on my second six month dose of Eligard and it should be done in May of this year. In November 2023, I had my first PSA test since SRT and it was .008 ng/mL. I just got
I had RP in January of 2023, started ADT in May of 2023 and went through 38 session of SRT between July and August. In am currently on my second six month dose of Eligard and it should be done in May of this year. In November 2023, I had my first PSA test since SRT and it was .008 ng/mL. I just got
toyman79912
in
Advanced Prostate Cancer
6 months ago
low resting heart rate
Hi All, I have Low resting heart rate, regardless of upping dose. I’ve upped my T3 meds from 20mcg to 25mcg and I take 100mcg of Levo and my resting hr stays at 52/51bpm my resting heart rate was the same at 15mcg T3 too. Initially when I up the dose for 2-3 days resting heart rate will increase to
Hi All, I have Low resting heart rate, regardless of upping dose. I’ve upped my T3 meds from 20mcg to 25mcg and I take 100mcg of Levo and my resting hr stays at 52/51bpm my resting heart rate was the same at 15mcg T3 too. Initially when I up the dose for 2-3 days resting heart rate will increase to
Thyroid_mum
in
Thyroid UK
1 month ago
Can anyone comment on my daughter's blood tests and advise what - if anything - we should do next?
My daughter is 18. I first requested blood tests with the GP when she was 15. This was during covid. I had to fight over the phone for them but she'd put on weight rapidly, she especially looked to be retaining fluid in her legs, feet, hands and face. Other symptoms = tiredness, slow movements, dry eyes
My daughter is 18. I first requested blood tests with the GP when she was 15. This was during covid. I had to fight over the phone for them but she'd put on weight rapidly, she especially looked to be retaining fluid in her legs, feet, hands and face. Other symptoms = tiredness, slow movements, dry eyes
ReaCoe
in
Thyroid UK
1 month ago
Why does Levothyroxine cause weight gain if it treats hypothyroidism, weight gain being a hypo symptom?
Shouldn't it help rectify hypo symptoms not make them worse? This baffles me! I wish I could revert back to Levothyroxine and use it together with T3 as NDT is extortionately priced, and not working brilliantly for me anymore, however, weight gain is my biggest fear, and I read so much about this on
Shouldn't it help rectify hypo symptoms not make them worse? This baffles me! I wish I could revert back to Levothyroxine and use it together with T3 as NDT is extortionately priced, and not working brilliantly for me anymore, however, weight gain is my biggest fear, and I read so much about this on
MindfulMoments
in
Thyroid UK
1 month ago
PSA holding low after all!!
As I complained a couple of months ago that PSA could be increasing, today the PSA moved a bit down from 0.03 3 months ago to 0.01 today :-), so I needed to write a few words here about my feelings. With a warm-hearted attitude, somehow enthusiastic but foolish too, as these things are never static,
As I complained a couple of months ago that PSA could be increasing, today the PSA moved a bit down from 0.03 3 months ago to 0.01 today :-), so I needed to write a few words here about my feelings. With a warm-hearted attitude, somehow enthusiastic but foolish too, as these things are never static,
Paulo1968
in
Advanced Prostate Cancer
6 months ago
3 month PSA post RT/ADT, low enough?
51, diagnosed at age 50 (Pirad 5 w/ ECE, 3+4 (20%), PSA 10.1, negative PSMA, Decipher high 0.84). I received SBRT treatment at UCLA in late October, 2023 (finished 10/25). I’ve been on ADT since October 16, 2023 and am scheduled to end ADT this March. I had my first follow up PSA test on 1/19 and it
51, diagnosed at age 50 (Pirad 5 w/ ECE, 3+4 (20%), PSA 10.1, negative PSMA, Decipher high 0.84). I received SBRT treatment at UCLA in late October, 2023 (finished 10/25). I’ve been on ADT since October 16, 2023 and am scheduled to end ADT this March. I had my first follow up PSA test on 1/19 and it
sptill72
in
Prostate Cancer Network
6 months ago
Thyroid uptake scan results
hi folks, In February I was diagnosed as hyperthyroid. My T4 was high at 38 (ref range 11-22). TPOAb high at 178 (range 0-35). TRAb negative at 3 (ref 0-3.3). I was referred recently for a thyroid uptake scan to conclude Graves diagnosis. Findings: The thyroid gland is not enlarged however there
hi folks, In February I was diagnosed as hyperthyroid. My T4 was high at 38 (ref range 11-22). TPOAb high at 178 (range 0-35). TRAb negative at 3 (ref 0-3.3). I was referred recently for a thyroid uptake scan to conclude Graves diagnosis. Findings: The thyroid gland is not enlarged however there
Hungryallthetimes
in
Thyroid UK
1 month ago
T3 in Crete
Hi, I am going to Crete and would like to pick up some T3, has anyone been recently and is easy to buy? Thanks very much.
Hi, I am going to Crete and would like to pick up some T3, has anyone been recently and is easy to buy? Thanks very much.
Bollieforme
in
Thyroid UK
1 month ago
SC5NA Gene mutation
hey, I’ve just been diagnosed with an SC5NA gene mutation after having genetic testing done which has identified the cause of my Brugada, I’ve now been advised I’m at risk of cardiomyopathy. Has anyone else experienced this diagnosis and can offer any advice?
hey, I’ve just been diagnosed with an SC5NA gene mutation after having genetic testing done which has identified the cause of my Brugada, I’ve now been advised I’m at risk of cardiomyopathy. Has anyone else experienced this diagnosis and can offer any advice?
Lilbandit88
in
British Heart Foundation
1 month ago
Follow up
I had a follow up appt with my Dr yesterday. Told her I am down from 10 mg ropinorole to 3 mg with the help of 25 mg tramadol when needed. She thought that was great but does not want me to use tramadol. She said it causes Rls. She gave me gabapentin 300 mg. to try instead of Tramadol. I asked about
I had a follow up appt with my Dr yesterday. Told her I am down from 10 mg ropinorole to 3 mg with the help of 25 mg tramadol when needed. She thought that was great but does not want me to use tramadol. She said it causes Rls. She gave me gabapentin 300 mg. to try instead of Tramadol. I asked about
ParisianTN55
in
Restless Legs Syndrome
1 month ago
Orchidectomy vs ADT
For anyone who had the bilateral orchidectomy, I would like some advice for my husband. When was it done? Before or after BCR occurred? What are the side effects? Do you take any other ADT meds after? How is your QOL and is there anything you'd do differently. He had RP in Dec 2021. No other treatment
For anyone who had the bilateral orchidectomy, I would like some advice for my husband. When was it done? Before or after BCR occurred? What are the side effects? Do you take any other ADT meds after? How is your QOL and is there anything you'd do differently. He had RP in Dec 2021. No other treatment
tn12
in
Advanced Prostate Cancer
6 months ago
Experiences of NDT v Levo and Lio
Hello again, I have been trialling NDT (2 grains since mid March 2024. I was previously on 75mcg Levo and 10mcg Lio (from NHS Endo) but still had symptoms. Both T4 and T3 levels are better on NDT yet I’m not feeling improvement. The private GP I saw increased my dose to 2.25 grains and I felt jittery
Hello again, I have been trialling NDT (2 grains since mid March 2024. I was previously on 75mcg Levo and 10mcg Lio (from NHS Endo) but still had symptoms. Both T4 and T3 levels are better on NDT yet I’m not feeling improvement. The private GP I saw increased my dose to 2.25 grains and I felt jittery
Piglet1956
in
Thyroid UK
1 month ago
My Oligometastatic PCa Journey Continues...coming up on year 9!
It's been a while since I've posted. But wanted to offer a note of
encouragement
for those here that have
oligometastatic prostate cancer
. I was diagnosed in 2015 (227 PSA, Gleason 8, 1 MET in the spine) and still going strong. After years of
hormone therapy
, 6 rounds of
chemo
It's been a while since I've posted. But wanted to offer a note of
encouragement
for those here that have
oligometastatic prostate cancer
. I was diagnosed in 2015 (227 PSA, Gleason 8, 1 MET in the spine) and still going strong. After years of
hormone therapy
, 6 rounds of
chemo
JamesAtlanta
in
Advanced Prostate Cancer
6 months ago
Lupron Question.
I have been on Lupron since June 2022. September 2023 Abiraterone and 5mg of prednisone was added. Psa was 19 in Sept and dropped to 1.26 as of Jan. 11 2024. Since going on Abi when I get a monthly Lupron shot I have trouble sleeping that first night and mild flu like symptoms the next day. I have agreed
I have been on Lupron since June 2022. September 2023 Abiraterone and 5mg of prednisone was added. Psa was 19 in Sept and dropped to 1.26 as of Jan. 11 2024. Since going on Abi when I get a monthly Lupron shot I have trouble sleeping that first night and mild flu like symptoms the next day. I have agreed
Professorgary
in
Advanced Prostate Cancer
6 months ago
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