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Acalabrutinib
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Changing from ibrutinib to acalabrutinib
From what I read from others these are all symptoms of ibrutinib side effects, and that switching to
acalabrutinib
may solve the problem with no loss in protection. Are there any ramp up, or periods in which all pills should be discontinued during the change over?
From what I read from others these are all symptoms of ibrutinib side effects, and that switching to
acalabrutinib
may solve the problem with no loss in protection. Are there any ramp up, or periods in which all pills should be discontinued during the change over?
CCgroup
in
CLL Support
2 years ago
CLL/SLL Ongoing
Will be starting on
Acalabrutinib
soon but still feel good in myself although sometimes my mind does wonder on what the future holds
Will be starting on
Acalabrutinib
soon but still feel good in myself although sometimes my mind does wonder on what the future holds
uide3095
in
CLL Support
2 years ago
CLL Society ASH 2021 Highlights from Day 2 of ASH 2021! Dr. Brian Koffman gives up updates
Brian Koffman gives up updates on the reversible non-covalently binding BTKi (Bruton’s tyrosine kinase inhibitor) pirtobrutinib (formerly LOXO-305), another reversable BTKi known as MK-1026 (formerly ARQ-531), 3-year follow-up data from the Ascend Trial:
Acalabrutinib
vs Rituximab plus Idelalisib
Brian Koffman gives up updates on the reversible non-covalently binding BTKi (Bruton’s tyrosine kinase inhibitor) pirtobrutinib (formerly LOXO-305), another reversable BTKi known as MK-1026 (formerly ARQ-531), 3-year follow-up data from the Ascend Trial:
Acalabrutinib
vs Rituximab plus Idelalisib
bkoffman
CLL CURE Hero
in
CLL Support
2 years ago
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Fixed Duration A & O Phase 2 Study...anyone?
It's called: Phase 2 Time Limited Approach based on depth of Response to Front Line
Acalabrutinib
in combination with Obinutuzumab for CLL/SLL who achieve complete remission or partial remission with UMRD. Quite a mouthful!
It's called: Phase 2 Time Limited Approach based on depth of Response to Front Line
Acalabrutinib
in combination with Obinutuzumab for CLL/SLL who achieve complete remission or partial remission with UMRD. Quite a mouthful!
Bethro
in
CLL Support
2 years ago
Advantage of Acalabrutinib over Ibrutinib?
What are the advantages of
acalabrutinib
? Disadvantages? Has anyone else made this transition? How did it go?
What are the advantages of
acalabrutinib
? Disadvantages? Has anyone else made this transition? How did it go?
Ibru
in
CLL Support
2 years ago
Asking friends for pre-gathering precautions
My husband, currently on
Acalabrutinib
, would join us. We’ve asked that everyone be tested 2 days prior and not attend if they’ve traveled out of town (by air or otherwise) within the week before, nor if they’ve attended an indoor gathering of more than 25 people.
My husband, currently on
Acalabrutinib
, would join us. We’ve asked that everyone be tested 2 days prior and not attend if they’ve traveled out of town (by air or otherwise) within the week before, nor if they’ve attended an indoor gathering of more than 25 people.
OaktownA
in
CLL Support
2 years ago
Acalabrutinib
Still no antibodies because
Acalabrutinib
being a targeted drug affects the immune system. So no mixing still, all in good time. Stay safe and well.
Still no antibodies because
Acalabrutinib
being a targeted drug affects the immune system. So no mixing still, all in good time. Stay safe and well.
kitchengardener2
in
CLL Support
3 years ago
what is your experience of acalabrutinib in CLL
I start
acalabrutinib
next week. I have been on wait and watch 10 years. 2 months ago I developed a large firm and smooth swelling on my jaw.
I start
acalabrutinib
next week. I have been on wait and watch 10 years. 2 months ago I developed a large firm and smooth swelling on my jaw.
benchica
in
CLL Support
3 years ago
What to expect when starting Acalabrutinib
Will
Acalabrutinib
treatment improve fatigue symptoms?
Will
Acalabrutinib
treatment improve fatigue symptoms?
Joffre1
in
CLL Support
3 years ago
CALQUENCE (Acalabrutinib) not working right after Covid vaccination?
I was on
Acalabrutinib
for over two years without any complications or side effects. I was vaccinated in January 2021. About 3 months after that I started to have issues with medication. I had to switch to Zanubritinb about month ago.
I was on
Acalabrutinib
for over two years without any complications or side effects. I was vaccinated in January 2021. About 3 months after that I started to have issues with medication. I had to switch to Zanubritinb about month ago.
pragnar
in
CLL Support
3 years ago
Getting antivirals UK
I’m on
Acalabrutinib
, have had 2 jabs followed by covid infection and a test that was negative for antibodies. I have since had the the 3rd jab too. Obviously with my history I am concerned- and I have been so careful too!!!
I’m on
Acalabrutinib
, have had 2 jabs followed by covid infection and a test that was negative for antibodies. I have since had the the 3rd jab too. Obviously with my history I am concerned- and I have been so careful too!!!
camper2
in
CLL Support
2 years ago
Valneva COVID vaccine
and wondered if anyone knew more about it and whether it would be useful for us immunosuppressed people on the likes of
Acalabrutinib
. Would it be better than Pfizer? Is it approved yet?
and wondered if anyone knew more about it and whether it would be useful for us immunosuppressed people on the likes of
Acalabrutinib
. Would it be better than Pfizer? Is it approved yet?
camper2
in
CLL Support
3 years ago
O & V Treatment - ALC Doubling
It's nice that we have treatment choices here in the UK of either a time framed treatment such as O &V or a long term treatment such as
Acalabrutinib
but more importantly how effective they are. I opted for the 12 month Obi + V course as i'm 51. That's it.
It's nice that we have treatment choices here in the UK of either a time framed treatment such as O &V or a long term treatment such as
Acalabrutinib
but more importantly how effective they are. I opted for the 12 month Obi + V course as i'm 51. That's it.
C0llin
in
CLL Support
2 years ago
Acalabrutinib Plus Venetoclax and Obinutuzumab Achieves High Bone Marrow uMRD Rate in Chronic Lymphocytic Leukemia - CLL
Acalabrutinib
, venetoclax, and obinutuzumab as frontline treatment for chronic lymphocytic leukaemia: a single-arm, open-label, phase 2 study.
Acalabrutinib
, venetoclax, and obinutuzumab as frontline treatment for chronic lymphocytic leukaemia: a single-arm, open-label, phase 2 study.
AussieNeil
Administrator
in
CLL Support
3 years ago
Acalabrutinib and mouth sores
Hi everyone, My wife Gabriella started
Acalabrutinib
for CLL a couple of weeks ago and getting great results (lymph nodes in the neck area almost gone ) and very few side effects ( morning headaches taken of with a cup of coffee, thanks to a post I read ) Very painful mouth sore appeared a couple of
Hi everyone, My wife Gabriella started
Acalabrutinib
for CLL a couple of weeks ago and getting great results (lymph nodes in the neck area almost gone ) and very few side effects ( morning headaches taken of with a cup of coffee, thanks to a post I read ) Very painful mouth sore appeared a couple of
Sergi
in
CLL Support
3 years ago
Side effects of Acalabrutanib
Hi I've recently been diagnosed with CLL (March) and chose to start chemo taking
Acalabrutinib
. After the initial few weeks of nausea things seemed to settle down. My glands went down and my energy levels improved.
Hi I've recently been diagnosed with CLL (March) and chose to start chemo taking
Acalabrutinib
. After the initial few weeks of nausea things seemed to settle down. My glands went down and my energy levels improved.
Tomaljoe69
in
CLL Support
3 years ago
As any one with CLL tried Adaptogenic's mushrooms for stress reduction?
I have been taking
Acalabrutinib
for one month and feel okay, but on edge and reactive to every little upset. Thanks for your input, my friends 🙏🏼
I have been taking
Acalabrutinib
for one month and feel okay, but on edge and reactive to every little upset. Thanks for your input, my friends 🙏🏼
unairdefamille
in
CLL Support
3 years ago
Coughing a lot a lot of mucus.
Hi I’m really suffering on the
acalabrutinib
my bloods are getting better great but every morning I have a really bad chest coughing loads loads of horrible mucus I’ve sent a sample to the doctor I hope it’s going to pass it’s really hard to liv with has anyone else Had this it’s really quite depressing
Hi I’m really suffering on the
acalabrutinib
my bloods are getting better great but every morning I have a really bad chest coughing loads loads of horrible mucus I’ve sent a sample to the doctor I hope it’s going to pass it’s really hard to liv with has anyone else Had this it’s really quite depressing
scottfree
in
CLL Support
3 years ago
Information on chronic lymphocytic leukemia
Starting treatment next week with a infusion of obinutuzumab for 4 hours twice a week then off 28 days will do 6 cycles and start taking
acalabrutinib
twice a day for the rest of my life Wanting to see if anyone is doing this are has so I will know what to expect will it do any good or put it in to remission
Starting treatment next week with a infusion of obinutuzumab for 4 hours twice a week then off 28 days will do 6 cycles and start taking
acalabrutinib
twice a day for the rest of my life Wanting to see if anyone is doing this are has so I will know what to expect will it do any good or put it in to remission
William1955
in
CLL Support
3 years ago
CD49d
It’s been said that “cd49d + makes it more difficult for ibrutinib to do its job,” would this apply to the (BTK) class of treatments (
acalabrutinib
, etc.)?
It’s been said that “cd49d + makes it more difficult for ibrutinib to do its job,” would this apply to the (BTK) class of treatments (
acalabrutinib
, etc.)?
Lavinia-Blue
in
CLL America Support
2 years ago
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