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Anyone experience lung side effects?
I’m on Lupron and
Abiraterone
since Nov. 2021. No physical manifestations. No shortness of breath. I do 40 minutes of treadmill @3mph with mild hills three times a week. Strength the other three days with no problems. Otherwise pretty active for a 79yo.
I’m on Lupron and
Abiraterone
since Nov. 2021. No physical manifestations. No shortness of breath. I do 40 minutes of treadmill @3mph with mild hills three times a week. Strength the other three days with no problems. Otherwise pretty active for a 79yo.
Papa1
in
Advanced Prostate Cancer
1 year ago
Orgovyx vs. Lupron, (with Enzalutimide or Abiraterone).
My MO wants to start me on a 3-month Lupron injection for my next shot, then shortly thereafter add
Abiraterone
or Enzalutimde. I asked him about Orgovyx, as I do have some Coronary Calcium, and also have mild Hypertension.
My MO wants to start me on a 3-month Lupron injection for my next shot, then shortly thereafter add
Abiraterone
or Enzalutimde. I asked him about Orgovyx, as I do have some Coronary Calcium, and also have mild Hypertension.
Vp7174
in
Advanced Prostate Cancer
1 year ago
Genetics - Some answers but not all
TP53 outperforms other androgen receptor biomarkers to predict
abiraterone
or enzalutamide outcome in metastatic castration-resistant prostate cancer. Clin Cancer Res. 2019;25(6):1766–73. https://doi.org/10.1158/1078-0432.CCR-18-1943.
TP53 outperforms other androgen receptor biomarkers to predict
abiraterone
or enzalutamide outcome in metastatic castration-resistant prostate cancer. Clin Cancer Res. 2019;25(6):1766–73. https://doi.org/10.1158/1078-0432.CCR-18-1943.
spw1
in
Advanced Prostate Cancer
1 year ago
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Cause of Liver Enzymes increasing
I have stopped using all medication, outside my Prescribed
Abiraterone
/Prednisone. Questions: I’m scheduled to have my 2nd Docetaxel next Friday. Is it realistic to expect my enzyme numbers to respond that fast? How long can I wait between treatments without affecting efficacy?
I have stopped using all medication, outside my Prescribed
Abiraterone
/Prednisone. Questions: I’m scheduled to have my 2nd Docetaxel next Friday. Is it realistic to expect my enzyme numbers to respond that fast? How long can I wait between treatments without affecting efficacy?
TMcgee
in
Advanced Prostate Cancer
1 year ago
Hot flashes and Lupron
Since I stopped
Abiraterone
, the hot flashes are back. Real heavy, real often and accompanying them are intense mood swings. I'm going to look into estriadol patches becausee frankly I'm at my wits ends.
Since I stopped
Abiraterone
, the hot flashes are back. Real heavy, real often and accompanying them are intense mood swings. I'm going to look into estriadol patches becausee frankly I'm at my wits ends.
chickgreen
in
Advanced Prostate Cancer
1 year ago
Time for vacation???
I also started taking
abiraterone
in January 2023. What are your thoughts about taking a vacation from the Lupron and the
abiraterone
starting January 2024? Thanks for your feedback and insight!
I also started taking
abiraterone
in January 2023. What are your thoughts about taking a vacation from the Lupron and the
abiraterone
starting January 2024? Thanks for your feedback and insight!
Cyclingrealtor
in
Advanced Prostate Cancer
11 months ago
The Use of Low Dose Estradiol to Ameliorate the Effects of ADT on Bone Mass Density
It should be noted that
abiraterone
+ prednisone, as a second line therapy, was initiated in August 2020, ~58 months after ADT with leuprolide was started.
It should be noted that
abiraterone
+ prednisone, as a second line therapy, was initiated in August 2020, ~58 months after ADT with leuprolide was started.
PhilipSZacarias
in
Advanced Prostate Cancer
1 year ago
Abiraterone costs via insurance
Team, thought I would check to see what everyone's financial experience has been who are using generic
Abiraterone
Acetate. My BlueCross BlueShield uses CVS exclusively for handling all my meds. CVS is charging me/my insurance $9,650/m for generic
Abiraterone
.
Team, thought I would check to see what everyone's financial experience has been who are using generic
Abiraterone
Acetate. My BlueCross BlueShield uses CVS exclusively for handling all my meds. CVS is charging me/my insurance $9,650/m for generic
Abiraterone
.
Wildfun44
in
Advanced Prostate Cancer
1 year ago
Interesting paper summarising state of art (2022) for ADT
From Chapter 7 “All four agents (docetaxel,
abiraterone
, enzalutamide, and apalutamide) have been FDA-approved for the treatment of metastatic, castration-sensitive prostate cancer and are now listed as category 1 recommendations within the NCCN guidelines.81 Treatment choice between agents for metastatic
From Chapter 7 “All four agents (docetaxel,
abiraterone
, enzalutamide, and apalutamide) have been FDA-approved for the treatment of metastatic, castration-sensitive prostate cancer and are now listed as category 1 recommendations within the NCCN guidelines.81 Treatment choice between agents for metastatic
Graham49
in
Advanced Prostate Cancer
1 year ago
radiation whack-a-mole?
I've been taking androgen blockers (Eligard injections 90 days plus daily 1gm of
abiraterone
) for five years. The primary treatment in summer 2018 was external beam radiation.
I've been taking androgen blockers (Eligard injections 90 days plus daily 1gm of
abiraterone
) for five years. The primary treatment in summer 2018 was external beam radiation.
Johnkelsey
in
Advanced Prostate Cancer
10 months ago
PET/CT Scan Results
DX 8/21 Started ADT Lupron,
Abiraterone
, Prednisone. PSA <0.64 until 1/31 Blood work PSA .253. MO ordered PET Pyarify (F18 PSMA) Scan 02/14/2023. Results: Head/Neck, Chest, Abdomen/Pelvis – No suspicious physiologic activity elsewhere.
DX 8/21 Started ADT Lupron,
Abiraterone
, Prednisone. PSA <0.64 until 1/31 Blood work PSA .253. MO ordered PET Pyarify (F18 PSMA) Scan 02/14/2023. Results: Head/Neck, Chest, Abdomen/Pelvis – No suspicious physiologic activity elsewhere.
alperk
in
Advanced Prostate Cancer
1 year ago
Bipolar Androgen Therapy Followed by Androgen Receptor Inhibition as Sequential Therapy for Prostate Cancer
Second, in men with CRPC progressing on
abiraterone
, BAT can be considered as part of sequential therapy with an antiandrogen based on results from the TRANSFORMER study. Importantly, BAT should always be given in conjunction with ongoing ADT.
Second, in men with CRPC progressing on
abiraterone
, BAT can be considered as part of sequential therapy with an antiandrogen based on results from the TRANSFORMER study. Importantly, BAT should always be given in conjunction with ongoing ADT.
pjoshea13
in
Fight Prostate Cancer
1 year ago
Too soon to be concerned?
., but, been getting bloodwork every one to two weeks lately as WBC count hasn't come back to normal since final chemo (Oct 24, 2022) and restarted
abiraterone
about 6 weeks ago. Since I've been getting CBC and CMP each time, I also get PSA tested. The past 2 weeks my PSA has gone up a little.
., but, been getting bloodwork every one to two weeks lately as WBC count hasn't come back to normal since final chemo (Oct 24, 2022) and restarted
abiraterone
about 6 weeks ago. Since I've been getting CBC and CMP each time, I also get PSA tested. The past 2 weeks my PSA has gone up a little.
rsgdmd
in
Advanced Prostate Cancer
1 year ago
Four years of ADT, pros/cons
Four years of Lupron +
abiraterone
Pros: I'm still alive and castration sensitive, spine met not growing or painful Cons: Zero libido, muscle loss, fat gain, hot flashes, blueberry-size testicles, BP increase, body hair loss...
Four years of Lupron +
abiraterone
Pros: I'm still alive and castration sensitive, spine met not growing or painful Cons: Zero libido, muscle loss, fat gain, hot flashes, blueberry-size testicles, BP increase, body hair loss...
Gearhead
in
Advanced Prostate Cancer
1 year ago
Substitute Eplerenone for Prednisone with Zytiga?
The reason to give prednisone with
abiraterone
is to reduce the increase in aldosterone caused by zytiga inhibition of cortisol which leads to an increase in ACTH and in Aldosterone a hormone which is not blocked by
abiraterone
.
The reason to give prednisone with
abiraterone
is to reduce the increase in aldosterone caused by zytiga inhibition of cortisol which leads to an increase in ACTH and in Aldosterone a hormone which is not blocked by
abiraterone
.
garyjp9
in
Advanced Prostate Cancer
2 years ago
State of shock
He put me on
Abiraterone
1000mg Daily 5mg Prednisone daily Starting 8/1/2021 PSA 60 within 30 day went to undetectable.
He put me on
Abiraterone
1000mg Daily 5mg Prednisone daily Starting 8/1/2021 PSA 60 within 30 day went to undetectable.
joeydashoe
in
Advanced Prostate Cancer
1 year ago
Would like Opinions about Continuing on Pluvicto Trial
Had radiation for 2 months and was on
Abiraterone
for 2 years.
Abiraterone
stopped working. PSA started to rise to 9.3. I have been getting Cat Scans, PSMA and Bone scans. I enrolled in Pluvicto trial in September 22. I wasn’t selected for Pluvicto until the scans get worse.
Had radiation for 2 months and was on
Abiraterone
for 2 years.
Abiraterone
stopped working. PSA started to rise to 9.3. I have been getting Cat Scans, PSMA and Bone scans. I enrolled in Pluvicto trial in September 22. I wasn’t selected for Pluvicto until the scans get worse.
spolyu
in
Advanced Prostate Cancer
1 year ago
Need meal ideas for low-dose abiraterone
My husband (dx Oct '22, PSA 270, advanced PCa with extensive bone mets), is about to start the low-dose
abiraterone
regimen (250mg with small low-fat meal - 300 calories, max 9g of fat) (this has been discussed with two oncologists, including one at Dana Farber, so please - respect our decision).
My husband (dx Oct '22, PSA 270, advanced PCa with extensive bone mets), is about to start the low-dose
abiraterone
regimen (250mg with small low-fat meal - 300 calories, max 9g of fat) (this has been discussed with two oncologists, including one at Dana Farber, so please - respect our decision).
HikerWife
in
Advanced Prostate Cancer
1 year ago
Update on my father. Triplet therapy?
I've been reading about the benefits of giving
Abiraterone
(Zytiga) early versus later as part of triplet therapy and also told his doctor about that but I am not sure what the future steps will be. What do you think - should we be more persistent about early
Abiraterone
?
I've been reading about the benefits of giving
Abiraterone
(Zytiga) early versus later as part of triplet therapy and also told his doctor about that but I am not sure what the future steps will be. What do you think - should we be more persistent about early
Abiraterone
?
gio2x
in
Advanced Prostate Cancer
1 year ago
Father completed 6 Docetaxel cycle among triplet therapy , Will 3 more cycles beneficial or not ? PSA -2.287
Diagnosed in August , started with bl orcheidectomy ADT ,
abiraterone
and docetaxel within 3weeks . Docetaxel chemo and all other simultaneous triplet is well tolerated , apart from fatigue grade 2 no other side effects.
Diagnosed in August , started with bl orcheidectomy ADT ,
abiraterone
and docetaxel within 3weeks . Docetaxel chemo and all other simultaneous triplet is well tolerated , apart from fatigue grade 2 no other side effects.
Helllfire
in
Advanced Prostate Cancer
1 year ago
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