Hi everyone , Father , 56 age ,completed 6 docetaxel 3 weekly cycles (dose75mg/m2 , his total dose -135mg ), his blood reports are
HB-8.7 , Platlets - 160, Alkaline Phosphate - 865 ,
PSA - 2.287
All other test like liver ,kidney profile , glucose within normal range .
(Diagnostic PSA-385 , Alk phosphate -6795 ,Hb 9.9.)(PSA before chemo -32).
Diagnosed in August , started with bl orcheidectomy ADT , abiraterone and docetaxel within 3weeks .
Docetaxel chemo and all other simultaneous triplet is well tolerated , apart from fatigue grade 2 no other side effects.
PSA -- Dx -385 , Before 1st chemo -32, After 3rd chemo -9.03, After 6th chemo it is now -2.287
Similarly ALP also has consistent drop .
After going through Internet by reading research on optimal cycles of docetaxel and through HU community, I am of opinion that 3 more cycles will be highly beneficial .
But doctor during initial discussion said 6 cycles is standard . PSA drop till 2 is sufficient , other work will be done by abiraterone.
My father is also willing to go through more cycles of chemo if it benefits.
Please guide me how to go further on number of cycles of docetaxel , should I insist on more cycles or stop chemo cycles here only ?
Please provide any trial research or data regarding 9or 10 cycles is more beneficial if tolerated so that I can convince doctor for more no of cycles.
My appointment with Tata ,Hospital, Mumbai doctor is tomorrow . So please everyone guide me on this .