Hi All - I'm looking for advice in a rather special case - I've been on Lupron for a bit over a year, and on Ariraterone for about 8 months. Last month, my MO pulled me from Abiraterone because my blood pressure was out of control, and tripling the ARB that I am taking really did not seem like a great idea. The prior doubling of the medication gave only temporary relief.
Anyhow... Since I stopped Abiraterone, the hot flashes are back. Real heavy, real often and accompanying them are intense mood swings. I'm going to look into estriadol patches becausee frankly I'm at my wits ends. The ARB family of drugs that I take is associated with increased depression and suicide, and I really don't need the additional emotional pressure that I feel I am under now.
Does anyone else have an experience like this?
Written by
chickgreen
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I might as well be specific, regarding SSRI antidepressants:
"Paroxetine ( brand name: Brisdelle) is an SSRI and is the only nonhormonal therapy that is specifically approved for hot flashes in the United States. This medication has been used for many years for treating depression, but can be taken at a lower dose for hot flashes.
Although not approved for this use, other SSRIs such as citalopram (brand name: Celexa), and escitalopram (brand name: Lexapro) relieve hot flashes to similar degrees as is seen with paroxetine."
The one T_A mentioned below, venlafaxine (brand name: Effexor), is not an SSRI but an SNRI (serotonin and noradrenaline reuptake inhibitor).
Citalopram has all but eliminated my hot flashes, and, as noted below, my wife also says I’m more mellow. Lupron and abiraterone/prednisone for 5+ years.
That's why I quit ADT halfway through me two-year sentence; I couldn't stand the SEs, including the crying and depression. My T recovered and I got on an antidepressant, and I'm fine now, but I really did want to die for a while.
People tolerate ADT differently. Some barely notice; others blow their brains out. Almost everyone is somewhere in the middle.
Yeah, I'm like you, depression, crying and feeling like crap. Lupron was worse than any other aspect of PC treatment. But I did enjoy imagining many starving cancer cells screaming for mercy before they perish. My adt was to complement radiation therapy
I had regular hot flashes and occasional mood swings on Lupron. They all stopped when I switched to Orgovyx. It is a small, once daily pill. My anecdotal opinion is, that Orgovyx does everything Lupron does, only better and with fewer side effects. orgovyx.com/ Best of luck.
Sore Legs? In what area? My legs have been aching constantly particularly in the thighs, (and they're also huge) also I do get severe "Bone pain" in my shins occasionally. Been on Eligard, Zytiga and prednisone since June 2019
yes. Very painful lower leg pain that vanished after I started my ‘holiday’ except for some arthritis in my right knee that cortisone really helps. I don’t think I’m the only one. .
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Abiraterone added to Lupron
Off Lupron, and legs are stronger.
Overwhelming hot flashes. Orgovyx/Relugolix
Hot Flashes
ADT and hot flashes
