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A survey of open questions in adaptive therapy: Bridging mathematics and clinical translation, eLife, Review Article, Mar 23, 2023
Continuous
Abiraterone
or eNZalutamide in mCRPC (ANZadapt)[/i] [i]
https://www.clinicaltrials.gov/ct2/show/NCT05393791
[/i] BTW, the eLife Magazine website is a very rich resource for research of all types.
Continuous
Abiraterone
or eNZalutamide in mCRPC (ANZadapt)[/i] [i]
https://www.clinicaltrials.gov/ct2/show/NCT05393791
[/i] BTW, the eLife Magazine website is a very rich resource for research of all types.
cujoe
in
Fight Prostate Cancer
1 year ago
Atrial Fibrillation
Hello All , Ive been on Eligard , Zytiga , 250 mg ,
Abiraterone
5mg for 14 months , Just found out from a EKG I have paroxysmal A-Fib and PVC (premature ventricular contraction ) . The Dr. gave me a monitor to wear on my chest for 2 weeks . This was done at U of Chicago 2 days ago . I saw my V. A.
Hello All , Ive been on Eligard , Zytiga , 250 mg ,
Abiraterone
5mg for 14 months , Just found out from a EKG I have paroxysmal A-Fib and PVC (premature ventricular contraction ) . The Dr. gave me a monitor to wear on my chest for 2 weeks . This was done at U of Chicago 2 days ago . I saw my V. A.
reconjj
in
Advanced Prostate Cancer
1 year ago
Phase II 2020-0200 Clinical Trial
Had been on
Abiraterone
Acetate (AA) along with Lupron and Prednisone. My PSA dropped to 0.1 until recently I became castrate resistant. I was advised by my team at MD Anderson that my cancer was a strong variant type.
Had been on
Abiraterone
Acetate (AA) along with Lupron and Prednisone. My PSA dropped to 0.1 until recently I became castrate resistant. I was advised by my team at MD Anderson that my cancer was a strong variant type.
Z06505hp
in
Advanced Prostate Cancer
1 year ago
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understanding pathology reports
My diagnosis (prostate Adenocarcinoma ,dx 1/6/22 stage IV, widespread bone Metastasis base line PSA 1316,,I have been on degarelix
abiraterone
with prednisone for the last 16 months.
My diagnosis (prostate Adenocarcinoma ,dx 1/6/22 stage IV, widespread bone Metastasis base line PSA 1316,,I have been on degarelix
abiraterone
with prednisone for the last 16 months.
yardsailor
in
Advanced Prostate Cancer
1 year ago
Need Help with Next Gen ADT
Otherwise ZYTIGA® (
abiraterone
acetate) - his less preferred. I looked at side effects of both and see little to no difference other that
abiraterone
lists Infected nose, sinuses, or throat (cold) as a common side effect.
Otherwise ZYTIGA® (
abiraterone
acetate) - his less preferred. I looked at side effects of both and see little to no difference other that
abiraterone
lists Infected nose, sinuses, or throat (cold) as a common side effect.
swwags
in
Advanced Prostate Cancer
8 months ago
Four Years Results
Treatments: 1)Lupron shot every 3 months effective December 2019. 2)
Abiraterone
250 mg with a low-fat breakfast 3)Radiation to Pelvic 4 weeks PSA Results: Entire 2020 and 2021 <0.03 2022 3/29 0.04 5/10 0.21 PSMA scans done , Found one small lesion in front first rib 6/10 0.22
Treatments: 1)Lupron shot every 3 months effective December 2019. 2)
Abiraterone
250 mg with a low-fat breakfast 3)Radiation to Pelvic 4 weeks PSA Results: Entire 2020 and 2021 <0.03 2022 3/29 0.04 5/10 0.21 PSMA scans done , Found one small lesion in front first rib 6/10 0.22
Pheart2
in
Advanced Prostate Cancer
11 months ago
Orgyvux(relugolix) and Zytiga(abiraterone)
I have a question from one of my support group members. They are currently on Orgyvux. Doc wants to add Zytiga to their treatment. Will the ADT side effects be the same with the addition of Zytiga, or will they become worse? Seems like the side effects would be worse, if T is driven to a lower level
I have a question from one of my support group members. They are currently on Orgyvux. Doc wants to add Zytiga to their treatment. Will the ADT side effects be the same with the addition of Zytiga, or will they become worse? Seems like the side effects would be worse, if T is driven to a lower level
billd50
in
Advanced Prostate Cancer
7 months ago
Any coming back from this?
September 2022: Started
abiraterone
. PSA: 12.6. CT scan showed some decrease in prostatic mass but progression in other areas. October 2022: PSA: 24. November 2022: Started docetaxel chemotherapy in addition to
abiraterone
. PSA: 53.6. CT scan showed mixed response.
September 2022: Started
abiraterone
. PSA: 12.6. CT scan showed some decrease in prostatic mass but progression in other areas. October 2022: PSA: 24. November 2022: Started docetaxel chemotherapy in addition to
abiraterone
. PSA: 53.6. CT scan showed mixed response.
Worriedson9
in
Advanced Prostate Cancer
1 year ago
Nighttime incontinence
I am on Lupron and
abiraterone
now for about 9 months. Among other side effects, I have occasional bed wetting. I dont have daytime issues and never experienced any of that even immediately after surgery. However, on a completely random basis, I will wet the bed while sleeping.
I am on Lupron and
abiraterone
now for about 9 months. Among other side effects, I have occasional bed wetting. I dont have daytime issues and never experienced any of that even immediately after surgery. However, on a completely random basis, I will wet the bed while sleeping.
jmarsh
in
Advanced Prostate Cancer
1 year ago
Abiraterone 250mg shortage?
Anyone having trouble getting their
Abiraterone
Acetate 250mg. Rx filled lately? In mid January the Mail Order pharmacy my MO got me started with requested my Rx get switched to 500mg. tabs because of a nationwide shortage of the 250mg. tabs.
Anyone having trouble getting their
Abiraterone
Acetate 250mg. Rx filled lately? In mid January the Mail Order pharmacy my MO got me started with requested my Rx get switched to 500mg. tabs because of a nationwide shortage of the 250mg. tabs.
Shams_Vjean
in
Advanced Prostate Cancer
1 year ago
Nubeqa vs Abiraterone for post Docetaxel maintenance?
Thanks to the many on this board that offered suggestions I will soon complete a slightly modified triple therapy of ADT+ABI+Docetaxel. My challenges with side effects included eliminating Tylenol and reducing ABI for one cycle; and then, switching from 1000mg ABI on empty stomach to 250mg ABI+ 10mg
Thanks to the many on this board that offered suggestions I will soon complete a slightly modified triple therapy of ADT+ABI+Docetaxel. My challenges with side effects included eliminating Tylenol and reducing ABI for one cycle; and then, switching from 1000mg ABI on empty stomach to 250mg ABI+ 10mg
TMcgee
in
Advanced Prostate Cancer
1 year ago
Does or Has Anyone heard or read that PCA can Morp into Neuroendocrine Cancer while on Lupron or Orgovyx, Nubeqa or any other medication?
I’m on Firmagon every 28 days, Zytiga, (
Abiraterone
) and Prednisone since 07/2022. I have concerns if Anyone had their PCA Morp into Neuroendocrine Cancer or Small Cell Carcinoma while on Lupron or Orgovyx, Nubeqa etc, or any other medication prescribed.
I’m on Firmagon every 28 days, Zytiga, (
Abiraterone
) and Prednisone since 07/2022. I have concerns if Anyone had their PCA Morp into Neuroendocrine Cancer or Small Cell Carcinoma while on Lupron or Orgovyx, Nubeqa etc, or any other medication prescribed.
Shorehousejam
in
Advanced Prostate Cancer
9 months ago
The CRP:Albumin ratio & CRPC Survival
Dividing the sample according to the first line treatment chosen, we found OS of 26.25 vs 5.9 months (p < 0.05), 27.71 vs 22.57 months (p < 0.05) and 27.36 vs 23.75 months (p = 0.12), for docetaxel,
abiraterone
and enzalutamide, respectively.
Dividing the sample according to the first line treatment chosen, we found OS of 26.25 vs 5.9 months (p < 0.05), 27.71 vs 22.57 months (p < 0.05) and 27.36 vs 23.75 months (p = 0.12), for docetaxel,
abiraterone
and enzalutamide, respectively.
pca2004
in
Fight Prostate Cancer
11 months ago
Symptoms when ADT no longer works?
Taking
abiraterone
+ prednisone daily and Lupron shots twice a year. I am doing my best to live one day at a time but wonder what things will look like when the cancer becomes resistant. Does anybody know?
Taking
abiraterone
+ prednisone daily and Lupron shots twice a year. I am doing my best to live one day at a time but wonder what things will look like when the cancer becomes resistant. Does anybody know?
SandyBear2023
in
Advanced Prostate Cancer
1 year ago
Options
My husband has advanced prostate cancer, psa was 325 at diagnosis, has had one round of chemo, psa never got to single figures, we were told, don’t emphasise on the figures, two months after chemo, things not great, put on
Abiraterone
…, psa doubled every 2 weeks, last count was over 500, suggesting
My husband has advanced prostate cancer, psa was 325 at diagnosis, has had one round of chemo, psa never got to single figures, we were told, don’t emphasise on the figures, two months after chemo, things not great, put on
Abiraterone
…, psa doubled every 2 weeks, last count was over 500, suggesting
Roxy1968
in
Advanced Prostate Cancer
1 year ago
Leg Pain - 4th Week on Lupron
Hi Friends, I'm on 4th week of ADT (Lupron+
Abiraterone
). Yesterday I started feeling right upper leg pain in the quads area. I'm not sure whether it's bone or muscle pain. But it's getting worse. I can barely walk. At first I was thinking may be I strained it.
Hi Friends, I'm on 4th week of ADT (Lupron+
Abiraterone
). Yesterday I started feeling right upper leg pain in the quads area. I'm not sure whether it's bone or muscle pain. But it's getting worse. I can barely walk. At first I was thinking may be I strained it.
FightCancer101
in
Advanced Prostate Cancer
7 months ago
Fosfestrol ( oral Estrogen )/ Honvan for mCRPC progression ?
Current
therapy: ADT +
Abiraterone
+ Pred PSA has gradually increase from a nadir of .7 in july 2022 to 4.5 in april -2023 Latest PSMA - Sclerotic lesions in left iliac bone and sacrum , showing increase tracer uptake - Low grade PSMA avid aortocaval lymph node - ?
Current
therapy: ADT +
Abiraterone
+ Pred PSA has gradually increase from a nadir of .7 in july 2022 to 4.5 in april -2023 Latest PSMA - Sclerotic lesions in left iliac bone and sacrum , showing increase tracer uptake - Low grade PSMA avid aortocaval lymph node - ?
meowlicious99
in
Advanced Prostate Cancer
1 year ago
PSA Rising While on ADT and Abiraterone
I started
Abiraterone
in November 2022 and my PSA was 3.83. Over the last few months it dropped to 2.71, 2.50 and then 3.02 and now 3.28. Does this mean I am not responding to the
Abiraterone
any longer. I have only been on it for 3.5 months.
I started
Abiraterone
in November 2022 and my PSA was 3.83. Over the last few months it dropped to 2.71, 2.50 and then 3.02 and now 3.28. Does this mean I am not responding to the
Abiraterone
any longer. I have only been on it for 3.5 months.
Islandboy2021
in
Advanced Prostate Cancer
1 year ago
Tired, sick-feeling, slightly unsteady?
Abiraterone
, prednisone, Lupron, radiation. My PSA levels remain low and steady. However, for the last few weeks I have felt weaker than normal, slightly nauseated, and a little unsteady when walking. Pretty much all day long. Does anyone know if this is "normal?"
Abiraterone
, prednisone, Lupron, radiation. My PSA levels remain low and steady. However, for the last few weeks I have felt weaker than normal, slightly nauseated, and a little unsteady when walking. Pretty much all day long. Does anyone know if this is "normal?"
SandyBear2023
in
Advanced Prostate Cancer
1 year ago
Do you also have these symptoms?
Being treated with
abiraterone
and prednisone, Lupron twice a year, and had 28 radiation treatments in December 2022. I would like to know if others are experiencing the symptoms I am. Hot flashes and crying, due to Lupron. General weakness in body. Often somewhat depressed.
Being treated with
abiraterone
and prednisone, Lupron twice a year, and had 28 radiation treatments in December 2022. I would like to know if others are experiencing the symptoms I am. Hot flashes and crying, due to Lupron. General weakness in body. Often somewhat depressed.
SandyBear2023
in
Advanced Prostate Cancer
1 year ago
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