Hi Im new to the forum. I was diagnosed with ME/CFS approx 8 years ago and also have Sjogrens, restless legs and osteoarthritis. I am 57 and can no longer work due to fatigue and pain. I was prescribed duloxytine approx 3 years ago by CFS specialist. I am on highest dose of 120 mg a day. I had been fine on this until the pharmacy changed to different manufacturer last year. The first replacement I took for a number of months and developed gradual worsening side effects including palpatations, tremors and muscle spasms. I wrote to my GP to request previous supplier but the were unable to locate anything other than Cymbalta ( Eli Lilly). I agreed to try and am now on 4th month - I suffered severe headaches at first (& still do on occasion) but worse side effect is I've developed a burning sensation in my digestive system which occurs around 2 to 3 hours after consuming - I take lansopozol daily too - after a while I tried various alternative ways of taking these meds including after food, drinking plenty of water with them, eating food either side of meds etc. I have this week stopped my regular prescribed painkillers in case they were affecting my symptoms but it's still happening. Had anyone else had anything similar?
Burning sensation in digestive system ap... - Sjogren's Support
Burning sensation in digestive system approx 3 hours after taking Cymbalta - advice please?

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Sals1
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