Niraparib

[Merrymaid]

Been on niraparib 300mg for three weeks but told to stop due to low platelets, will have blood test in a week. Anyone had similar experience who went on to reduced dose that worked.

[Heidels]

I have been taking 200 mg daily now for 2 years.... so far, I have had good blood test results. I have read that many women who take 300 Mg have problems and their doctor reduces the amount.Try taking 200 mg a day.

[Merrymaid in reply to Heidels]

Thank you, think oncologist will reduce dose. Glad to hear you’ve been on it for two years successfully.

[Jenjill47]

Yes, this happened to me too. My platelets dropped alarmingly and I had to have three IV platelets infusions. I had no symptoms at all. My doctor gave me a 2 week break and then she started me on 100mg. Everything is fine now and she will gradually increase the dose in January. Good luck - you will be fine!

[Merrymaid in reply to Jenjill47]

Thank you for your positive reply.

[Seedlings in reply to Jenjill47]

Hi I'm restarting on Niraparib on Monday at 100 mg. The 200mg caused severe anemia. I'm just wondering how long you are on the 100dose??

Ann

[Seedlings]

Hi I was on 200mg Niraparib for four months but had to stop due to severe anemia. Had 5 transfusions in seven weeks. Am off it 7 weeks now but restarting on Monday at 100mg. Really hoping that I can tolerate it and that it works.

I hope that you get on well at the 200mg dose.

Ann

[Pianoplayer731021]

Hi, I started on 200 mgs., but was reduced to 100 mgs. This dose is much better for me, but I still had a few blood counts that made me take a weekly break once in awhile. I seem to be doing ok lately. Donna

[Merrymaid]

Thank you to everyone that replied, obviously it takes time to find correct dose, all we want is to be able to continue without too many side effects.

[Heidels]

I have seen many posts about women having problems when taking 300mg. I started out with 200 mg daily and it has been almost 1- 1/2 years now and I have had good lab results, no serious side effects. Platelets are low at times but nothing to worry about. Everyone experiences differntly. Try 200 mg daily

[a89251]

Started on 300 mg counts went down. Put on 200mg and worked for a few months and suddenly counts went down. Off for two months and now have been on 100 mg for about a month and so far ok.