Progression of Liver Mets

[Frenchgirl69]

I only have mets to my liver. I have been on Ibrance and letrezole since January 2023. Everything was going well. Yesterday I had a scan, and I have progression of liver mets and mild ascites. I see my oncologist on Monday. I am very frightened. I feel I am at the end of my journey. I had seven treatments of Taxol in 2022, but I couldn’t tolerate it. Please keep me in your thoughts and prayers.

[Notofu4me]

I am certainly no expert, but I know that the liver is a forgiving organ, and you can have a sizeable piece surgerically removed and survive. This is not your circumstance. There are meds for treatment for liver metastasis, and you need to stop worrying and listen to your oncologist tell you about your next phase. You are far from done yet.

[Gonnawin2]

I too have new liver mets as of a few months ago. I felt crushed by the news. However....I had 2 targeted radiation treatments called a Y-90. I don't know results as of yet but I can tell you that you are far from beaten. Please try to focus on all the positive areas and as notofu4me said...the liver is a forgiving and recoverable organ. 🌺

[Frenchgirl69 in reply to Gonnawin2]

Thank you for the kind words.

[Elle713 in reply to Gonnawin2]

Did you feel your liver metastasis? I know I have prior to it showing in scan.

[Gonnawin2 in reply to Elle713]

No, I didn't notice anything different. It was being detected though in liver enzymes and other blood work.

[kiwi67]

I had progression in liver mets in June scan. Started Capecitabine in July and September scan was very good, some mets too small to see and the largest one went from 15mm to 5mm, there are further treatment lines. Do you best to not overthink it (which by the way I did) and be kind to yourself. Best Wishes

[Frenchgirl69 in reply to kiwi67]

Thank you so much for the kind words.

[Merma]

Please don’t give up hope. There are so many choices of drugs and possibilities.

Thinking good thoughts and best wishes.

[Frenchgirl69 in reply to Merma]

Thank you so much for the kind words.

[Dflur]

who ever told you were at the end, did not know what they are talking about. There are so many treatment plans

[Onedayatatime2019]

Stay strong and positive! You are not at the end! You still have other meds available! Take care of yourself, take care of your body and surround yourself with positive people! One day at a time!

[Frenchgirl69 in reply to Onedayatatime2019]

Thank you so much for the kind words.

[BluHydrangea]

Try not to go to worse possible outcome. I had progression to liver in May and started Xeloda (cape) in June. My most recent scan was liver all clear. Confirming this with CT scan soon.

I had a liver biopsy( not bad at all) and they determined it was same breast cancer.

I’m sending you much love and good vibes. You have a long time to live!! ❤️

[Frenchgirl69 in reply to BluHydrangea]

Thank you for the kind words!

[Hazelgreen]

I agree with all the above comments! I have had breast cancer in my liver since 2019. Surgery removed much of it, but some remains.

Cancer seems to grow very slowly at my age of 79 years. You have also reached old age so no need to get over-excited.

I take ribociclib to keep the cancer small but I expect to die from old age, not cancer. Ask your oncologist to prescribe ribociclib, a pill you take at home.

[Logo999 in reply to Hazelgreen]

Do you take only ribociclib or endocrine therapy as well? What dosage of ribociclob do you tolerate? Do you have many side effects? Thank you so much

[Frenchgirl69 in reply to Logo999]

Since January of 2023, I have taken Ibrance 100 MG tablets and Letrezole 2.5 MG. I have no side effects from either.

[Hazelgreen in reply to Logo999]

I started with 600 mg of ribociclib (Kisqali) and 2.5 mg of letrozole in October, 2021. My cancer markers gradually shrank from a high of 190 to the normal range (less than 30) by the end of 2022. I find that cancer meds really sap my energy so I have gradually reduced them since then to 400 mg of ribociclib, week days only. (Ribociclib is always taken with letrozole because it serves to facilitate the action of the letrozole.)

As long as my cancer markers stay in the normal range, I'm happy. I was first diagnosed with breast cancer in 2006, and had a lumpectomy then. Thirteen years later, I woke up with a swollen right arm, and it became obvious that it had metastasized throughout my limbic system and other organs. (Actually, I first found that double tamoxifen worked to drastically lower my cancer markers, but my short-sighted oncologist refused to allow me to take double because this is not the recommended amount in Canada.)

[Frenchgirl69 in reply to Hazelgreen]

Thank you so much for the kind words.

[1711JPD]

Perhaps discuss with your onc the possibility of you going to see an interventional radiologist to see if you could be a candidate for liver ablation? I’ve had it done successfully twce and have been No Evidence of Active Disease for almost 18 months now. What you are facing now isnt easy and it is perfectly normal (to me anyway) to be frightened. You can do this! Sending you tons of positive thoughts and my very best wishes. Please keep us posted.

❤️

Joyce

[Frenchgirl69 in reply to 1711JPD]

I think I have so many mets on my liver that ablation wouldn’t be a possibility. I appreciate your kind words.

[Oberammergaux2]

Dear Frenchgirl,

Please do not despair! I know that may sound hollow but I have had numerous liver mets over the years. My first reaction was that it was “over”, get affairs in order, this was it. Not so.

I have an amazing radiation oncologist who has gone after every one of the mets with gamma knife radiation. In all, over the years, I have had 19 gamma knife rounds. If you have that option go for it. It’s not a ride at Disney but it’s fast, so much easier than being hooked up to chemo IVs and about the only side effect is some mild fatigue. I get a little tenderness in the liver area while it heals but I figure my poor liver has a right to be a little angry for a while.

If you’d like more info on the specifics, please let me know. Sending you a huge hug!

[Frenchgirl69 in reply to Oberammergaux2]

Thank you for the information. I have so many mets on my liver that abalation has never been discussed. I see my oncologist on Monday. I appreciate your kind words.

[Oberammergaux2 in reply to Frenchgirl69]

Please keep us posted!!! We’ll be with you in spirit Monday.

[Totheriver]

Hope all goes well for you!!

[Lilywallytootsie]

Please don't give up. There are many treatment options. Your doc will find the right one for you. Stage 4 is difficult for all of us. We are holding your hand. Blessings and prayers, Hannah

[love2golfwell]

I'm sorry you are going through this. I'm sure your oncologist will have some good treatment options for you. Please stay strong and don't give up hope. Sending you hugs and prayers.

[Elle713]

Hi Frenchgirl, I was on Ibrance/Faslodex for 18mos with only one bone met. Had major progression to bone and liver after 2 mos on Orserdu (as I was found to have the ESR1) mutation. Clearly that was not the right choice for me. I also could not tolerate Taxol back in 2019 (my original BC diagnosis)....Onc put me straight onto Trodelvy (IV Chemo). Its almost 6 mos now. Im tolerating it well, though I was unprepared for hair loss again. This time was very emotional and still is. I was very freaked out and panicked to go to IV chemo and still worry about the liver mets. However, there are many lines to try and many positive results. My Liver mets are stable at the moment and bone mets decreasing. It is not over for you....or for ME...but it is worrisome until you can know and understand your next treatment and discuss the options. Good Luck and keep us posted.

[WhippetX2]

Aren't the ladies in this group fantastic? Look, oncologists have a large number of options in their bag of tricks. The responses from above prove this. I know that the first time you hear news like this it is shocking. But, NEVER EVER give up.

[mariootsi]

You are in my thoughts and prayers!

[Felicia1228]

I think we cal all agree, progression definitely brings out the ‘cup half empty’ feeling. Depending on your type of BC, you may have many, many more options. I have read that some have had 10+ lines of treatment. Don’t get in your head! Feel the yucky emotions and spin them around to think about the next step! We are all behind you Warrior, regardless of your decision, of the next step! 🫶🏻🫶🏻

[RLN-overcomer]

Greetings Sister/Warrior 😇I pray all will be well. I believe our LORD is in the business of healing, and restoring us Amen Keep the faith🙏, and never ever give up, or give in😊. You will be an Over-comer. XoXo

[13plus]

I've got liver mets and showed some ascites in my last scans too. I've recently started Enhertu (I have Her2 low) so depending on your cancer's make-up that might be an option for you too. I think it works for triple negative too (not sure though). Before this I was Xeloda, chemo pill. Like others said, you still have options!