hello everyone
In July 1st 2022 I enrolled in a clinical trial with AZD (Faslodex in pills) and Capivasertib.
Unfortunately last PET scan is showing progression on my liver.
Options are Everolimus or Abemaciclib and IV chemo: Doxil.
My onc strongly recommends Doxil.
Obviously I am scared of IV chemo and was wondering if you could share your experiences with Doxil with me please.
How efficient was it ? What about side effects ?
Thank you very much !
Helene
I was on Doxil (in Italy it’s Caelyx) for about five months with no side effects. Ask your onc but this treatment should preserve your hair. I had a very good PET scan after two months, but when it stopped working after three months I had new mets in bones and again in breast (where I was NED for two years) and widespread mets in liver. I wish it worked longer… it’s a good treatment. My blood tests were perfect and I had a much better quality of life than when on Ribociclib.
I am somewhat shocked to hear you had no side effects on IV chemo. My experience was the ACT chemo regimen back in 2005 when I was first diagnosed bc and it was tough! Different drugs though so I guess they’re not all bad
I think that things changed a lot during the years. I suggest you to have a port installed, that’s good for your veins
They have changed a lot since then for sure. Even for mets patients. I think of a whole group of friends I had who had bc, starting back around 2008/9, who then later developed mets dx, and many of that group died within less than a decade. They just didn't have the treatment options we have today! It's very humbling
Hello Silver126
How are you ?
Doxil did not work for me. I did not have many side effects except fatigue and neuropathy in hands and feet. I did not loose my hair.
Which treatment did you start after it please ?
I hope you are doing well.
Helen
I’ve got bone and liver mets which have both progressed this year. I just started Everolimus. I guess your doctor’s suggestion might depend on the status of how big the liver mets are and the function? Like I have several lesions but nothing too big, and the liver function is quite good
My liver functions were good and I only had three small mets. My onc tried Everolimus and Exemestane before Doxil, but it was the only treatment I tried that didn’t function at all. I hope it works on you, we’re all different!
Thanks at the moment I’m doing fine, ready for Christmas 🎄
Food during treatment 
Paclitaxel, Taxol, Onxal IV chemotherapy treatment anyone? 
What’s next after Piqray?
To port or not to port
Doxil/Caelyx 15-3 Doubled
