hello everyone
In July 1st 2022 I enrolled in a clinical trial with AZD (Faslodex in pills) and Capivasertib.
Unfortunately last PET scan is showing progression on my liver.
Options are Everolimus or Abemaciclib and IV chemo: Doxil.
My onc strongly recommends Doxil.
Obviously I am scared of IV chemo and was wondering if you could share your experiences with Doxil with me please.
How efficient was it ? What about side effects ?
Thank you very much !
Helene
I was on Doxil (in Italy it’s Caelyx) for about five months with no side effects. Ask your onc but this treatment should preserve your hair. I had a very good PET scan after two months, but when it stopped working after three months I had new mets in bones and again in breast (where I was NED for two years) and widespread mets in liver. I wish it worked longer… it’s a good treatment. My blood tests were perfect and I had a much better quality of life than when on Ribociclib.
I am somewhat shocked to hear you had no side effects on IV chemo. My experience was the ACT chemo regimen back in 2005 when I was first diagnosed bc and it was tough! Different drugs though so I guess they’re not all bad
I think that things changed a lot during the years. I suggest you to have a port installed, that’s good for your veins
They have changed a lot since then for sure. Even for mets patients. I think of a whole group of friends I had who had bc, starting back around 2008/9, who then later developed mets dx, and many of that group died within less than a decade. They just didn't have the treatment options we have today! It's very humbling
Hello Silver126
How are you ?
Doxil did not work for me. I did not have many side effects except fatigue and neuropathy in hands and feet. I did not loose my hair.
Which treatment did you start after it please ?
I hope you are doing well.
Helen
I’ve got bone and liver mets which have both progressed this year. I just started Everolimus. I guess your doctor’s suggestion might depend on the status of how big the liver mets are and the function? Like I have several lesions but nothing too big, and the liver function is quite good
My liver functions were good and I only had three small mets. My onc tried Everolimus and Exemestane before Doxil, but it was the only treatment I tried that didn’t function at all. I hope it works on you, we’re all different!
Thanks at the moment I’m doing fine, ready for Christmas 🎄
Allergic reaction to Doxil, my first ever chemo infusion 
Moving on from Xeloda to Doxil
My cancer markers have jumped from 104 to 483 after two weeks on afinitor. My doctor now wants to put me on Doxil. Any one else had this?
Food during treatment 
To port or not to port
