Faslodex + Ibrance - new mets

[Goga156]

Hi everyone! My mother is on ibrance and faslodex for 15 cycles. she had pelvic metastases that are still under control, but there are new ones on her spine. she will continue to receive the same therapy. Does anyone have a similar experience? is it possible to keep the disease under control even though there are new metastases? we are very worried.

[OneLump22]

I'm not sure. I am also on Ibrance and Faslodex + Xgyva, but have not had any new mets. However, my Onc switched me to Ibrance from Aromasin because I developed a new tumor in the abdominal wall of my plural sack while on that. I've only been on it for a year now.

[Urca]

I think it is possible to have the same therapy even if there are new mets. I was told so by my oncologists. In January a pet showed two new metastasis on my ribs, left and right, while the liver metastasis I had in my liver was still NED. For this reason they decided to go on with Kisqali plus Faslodex. Actually, after a TC , they saw they were not new metastasis, but two broken ribs. I had had a terrible bronchitis for almost two months and had broken my ribs in two spots.

Anyway their choice would have been to go on with the old therapy because it had been working well for 2 years and a half and the first metastasis was still invisible.

[Goga156 in reply to Urca]

thank you for your reply. what is TC? my mom's CT shows possible degenerative changeso or secondaryism on the spine . and MR shows primarily secondary changes without bone destruction.

[OneLump22 in reply to Urca]

I also have a small fracture in one of my ribs, but don't have a clue how I got it! I threw up once I forget how long ago, but it must have been before my diagnosis because I knew nothing til they took chest x-rays & MRIs during my treatments to see how far my cancer had meted. Drs. : "Well, we found it here & here. Nothing in the lungs, but it looks like you cracked a rib."

Me: 😳 "Huh?!"

[Urca]

Sorry, I am Italian. I try to communicate but especially with acronyms I use the Italian term!! It's CT in English

[Goga156 in reply to Urca]

oh neighbor! I am Croatian. thank you very much for your answer, it has a positive effect on me.

[Jorgit]

How did they find out the new pelvic methastasis? Through a CT-scan, a PET-scan? Did she go through a gammagraphy as well? PET-scan tend to give sometimes false positives as a minor injury, an infection, a fracture or even the position itself while the scanning procedure turns into an increase uptake, offering misleading information. On the other hand, though the risk of fractures increases, bone is a hard tissue, while should she have a new merhastasis on a soft tissue such as a lung or liver (vital organs) the teatment approach would be different. The longer you can squeeze a treatment before switching to a new one, the best. Ask your oncologist so they may clarify a bit more and ease your worries. Please, let us know and all the best.

[Goga156 in reply to Jorgit]

My mother dont have new pelvic mets (old are stable). now CT shows osteolytics lesions possible degenerative changes or secondaryism on the spine and MR shows lesions primarily correspodent to metastases without bone destruction.

[OneLump22 in reply to Goga156]

🙏 God bless & keep your mother.

[Jorgit]

Sorry I misread your message as pelvic instead of spine...in this case an MRI can give further information as well...is she referring nerve or any other kind of pain secondary to the metastasic osteolytic lesions? If so, maybe they could consider along the way, "local" radiotherapy treatment. At the end of the day, the clinic (symptoms of the patient, how she feels) is the primary data to take into consideration to make decissions. Kindes Regards.

[Goga156 in reply to Jorgit]

she will receive local radiotherapy. . she dont have strong pain for now.. thank you for your reply and kind regards!

[DianaSav]

yes I have had the same thing happen pelvis Mets only now one or two spots on spine! My dr said that sometimes starting meds the Mets will light up more ( ones that were there prior that the scans didn’t see because they were to small to catch) bone Mets can look worse as they heal! Just hang in there and give it some time and then see how it goes

[Goga156 in reply to DianaSav]

thanks for reply. what medicines do you use and how long?

[Jaynikan in reply to DianaSav]

How often do you take tests to check Mets please also tell what tests ct scan .pet scan etc

[Goga156 in reply to Jaynikan]

every 3 months CT scan

[Jaynikan in reply to Goga156]

Thanks

[PJBinMI]

It's great to read so many reassuring replies here! I'm a long timer with metastatic bc (19 years this month!) and my own mother died from lung cancer. For me, my mother's cancer was more emotionally upsetting than having cancer myself. Our moms are such important people in our lives! I think one reason I've done so well for so long is that my oncs havwe been slow to change treatment meds for me. I got the most time from Faslodex, over 9 years. I had bone mets only until about four years ago. Since then I've had cancerous tissue show up in a ureter, surface of my cerebellum. lymph nodes putting pressure on the nerves into my right hand, and in my abdomen, putting pressure on my small intestine. I've has surgery, and radiation and only recently had some actual chemotherapy as the cancer switched from E + to triple negative. Some of us do well for long periods of time. Stable mets in the liver is very good news for your mother! I hope she will do well for many more years!

[Goga156 in reply to PJBinMI]

congratulations and thenk you for reply!Have you had metastases since the first diagnosis?

[Mcangel11]

I would ask if you should change chemo..there are so many and chemo gets smart after awhile and the cancer gets through. I am not a doctor but a nurse for 40 years and I would ask. I am going to look it up alsoRoxanne

[Goga156]

update: unfortunately after 3 months CT showed progression in the liver (multiple lesions). however, a new lesion 3 months ago indicated that ibrance and faslodex had stopped working.