Going back on Ibrance: My onc and I... - SHARE Metastatic ...

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Going back on Ibrance

Granny333 profile image
42 Replies

My onc and I made decision for me to try Ibrance 75. I can’t remember how to take dosage other than 21 on and 7 off. Can anyone help?

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Granny333 profile image
Granny333
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42 Replies
SeattleMom profile image
SeattleMom

Hello! Your oncologist will be providing you with the dosing schedule. God bless you!

Linda. 💗💗🙏🏻🙏🏻

Claireperth profile image
Claireperth

it is usually 21 on and 7 off. Some people have been taking 5 on and 2 off due to an intolerance to the 21 on without a stop. If you don’t have any issues with Ibranc then stick to what is written on the label 🌸

Granny333 profile image
Granny333 in reply to Claireperth

thanks

Aprilfoolz1 profile image
Aprilfoolz1

hi granny333, I take it in the morning. I try to take it at the same time every day for 21 days . After my week off I go in on day 28 for a blood test to check my white blood count. I am also on 75 mg and have been for 2 years (3 years and 4 months total on Ibrance ).

Hi I am on same 75 ibtance

3 weeks are in a package separate..

21 days on

7 days off

Hugs

Granny333 profile image
Granny333 in reply to

🙂

Buffwright profile image
Buffwright

It has been a while since I was on Ibrance. I recall reading in scientific literature that it should be taken with protein and fat rich food for best metabolism, but the doctor never mentioned it. I took it in the evening.

in reply to Buffwright

I have a Boost drink every other day for protine ..strawberry flavor..

Helps the white blood cells

Hugs

Southside25 profile image
Southside25

I talked my onc into letting me take Ibrance on a 5/2 schedule. Five days on, 2 days off. I started at 150, reduced to 100 and then to 75. I've read that the 5/2 schedule is getting more common. It's easier on the system and helps neutrophil levels to be better then when on the 21/7 schedule. I was on 5/2 for almost 3 years before the Ibrance stopped working.

Granny333 profile image
Granny333 in reply to Southside25

I am going to start out on 21 on and 7 off then if that is too much go on 5 on and 2 off

Granny333 profile image
Granny333 in reply to Southside25

Very interesting

Nocillo profile image
Nocillo

I’m on a 21 day on 14 days off schedule. Whatever you and your onc deem necessary.

Ntash01 profile image
Ntash01

Hi G…if you don’t mind me asking, how many treatments did you have before going back onto Ibrance? Did you have to have IV chemo inbetween and where are you in the world?

My next treatment is indefinite Taxol, which I’m trying to avoid!

Nx

Granny333 profile image
Granny333 in reply to Ntash01

No chemo just Astrazole and Ibrance

Southside25 profile image
Southside25 in reply to Granny333

I'm also interested that you went back on Ibrance. Onc put me on Piqray which brought on an awful side effect (I think - long story). I couldn't go on Kisquali so she started me on Verzenio which I'm tolerating fine so far - only 3 weeks. I've read that taking a "break" from Ibrance then going back on it can restart the positive response to the drug, but she won't put me back on it. So you were off for how long? and went back on?

Granny333 profile image
Granny333 in reply to Southside25

I was off around month and half

Granny333 profile image
Granny333 in reply to Ntash01

Did you get on your new meds?

Melpub profile image
Melpub

I always took my 75 mg tab in the morning with breakfast. Yes, 21 days and then seven days off. Some women take it at night because they feel it makes you sleepy. This wasn't a problem with me. My only side effects on this dosage were occasional breathlessness and dry, haystack hair.

Granny333 profile image
Granny333 in reply to Melpub

thank you

Beryl71 profile image
Beryl71

It can vary but mine is 21 days on and 7 off. Good luck. X

Granny333 profile image
Granny333 in reply to Beryl71

thanks

Chewysmom profile image
Chewysmom

hi Granny , I’m also on Ibrance I take 125 mg for 21 days in a row then take 7 days off . I hope this helps . If your not sure check with your oncologist. Have a blessed day

NPmary profile image
NPmary

The schedule doesn't change w I th a dosage change it's still 21 on 7 off unless your doc changes it.

oilermama profile image
oilermama

I say hydrate... and take it with something to eat. And I am with others who have blood work done before restarting the next cycle. I've been on it for five years...

Sharon0122 profile image
Sharon0122

You are correct 21 on and 7 off. Best wishes to you! Hugs

Granny333 profile image
Granny333 in reply to Sharon0122

🙂

Sharon0122 profile image
Sharon0122

any one know what the difference is in your body for 125, 100 and 75. I was on 125 for over a year and now lowered to 100. And I really hate those packages they come in, what a hassle, a jar would be better!

Claireperth profile image
Claireperth in reply to Sharon0122

yes, the packaging! I gave up on opening them up and gave the job to my husband so he can swear and mutter! 😄

Sharon0122 profile image
Sharon0122 in reply to Claireperth

my husband says he’s afraid to break the pill! But he does do laundry and empties the dishwasher! 😊

bubblystream profile image
bubblystream

can we go back on meds once we have progression while on them? I would love to go back to Ibrance. It worked 5 years for me. It was first line for me. Now on Taxil. 😞

Eliactida1955 profile image
Eliactida1955

that’s the way you take it. 3 weeks on and one off the another cycle. I took it for over 3 years and didn’t have much problem. I took 125 mg though.I hope you do well 🙏✝️🌹

Granny333 profile image
Granny333 in reply to Eliactida1955

thanks 🙂

Totheriver profile image
Totheriver

I take ibrance 75 ..two weeks on then two weeks off. I have tried many combinations and this is the one I tolerate the best.

Granny333 profile image
Granny333 in reply to Totheriver

That is what I am planning to do.

AuntC profile image
AuntC

I'm starting my 4th year. Tried all combinations finally settled on 75 mg. & 1 week on - 1 wk off. Good luck, you'll find the right combo.

Granny333 profile image
Granny333 in reply to AuntC

thanks🙂

TexasLady2 profile image
TexasLady2

3 weeks on Ibrance, 1 week off.

Granny333 profile image
Granny333 in reply to TexasLady2

thanks

morty87 profile image
morty87

21 days on, 7 days off. I always start a new pack on Sunday and I take it at bedtime. I used to take it after breakfast but I found myself getting motion sickness and nauseated. Taking it at bedtime has allowed me to be at home (I still teach fulltime - High School) and remain horizontal if I feel sick. I've had great success with Ibrance as I have been on it since 2018. I have labwork on the Friday "off" and the before starting the new pack on Sunday.

Blessings for good results.

ba5083 profile image
ba5083

My wife took hers before bed time. Seemed to work well for her. She could only 75mg due to low WBC numbers

Angelala60 profile image
Angelala60

where you on another med after Ibrance and now going back on it?

Granny333 profile image
Granny333

Yes, I was just on Antrazole

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