Hi all. Please excuse a silly question but, my wife and I are considering starting Capecitabine as she has TNBC mets to lung. Lung mets are progressing and we need to bring them into check. We want to do this at a lower dose chemo (I've read good things about low dose metronomic chemo with Mark Rosenberg amongst others).
What stops you from taking half or quarter of the tablet?
What doses does everyone else take?
Thank you in advance. X
I have been on Xeloda metronomic dosing since October last year. 1500mg daily.
Thank you..
I've been on it for over 6 months. I take 1,500mg twice daily, 2 weeks on and one week off continually.
I’ve been on Xeloda 4 months, 1,500 twice daily, on a week and off a week. Was wondering if you’d noticed an increase in urine elimination? Friend had to stop because of this and was curious if you had noticed this situation as well. Thanks for responding!
Hard to tell because I'm staying more hydrated than I used to which in turn leads to increase in urine output. My only complaint is hand and foot syndrome. It's affected me pretty significantly.
Makes sense…I am also staying very hydrated. Guess I noticed because I have 2 Nephrostomy bags with tubes to my kidneys that are suppose to empty 1,800 millimeters a day, and have noticed they are averaging about 800 with majority being bladder elimination the “normal” way. Would like to think cancer pressing against tubes to kidney has “eased” up allowing things to progress “normally”. However, when friend on this site mentioned stopping Xeloda because of severe increase in urination and wearing “mega pads” that didn’t even work, had me concerned.
Yes, hand and foot is also a side effect which thankfully hasn’t affected me yet. Keep Aquafor ointment and socks on my feet and Udderly Smooth on my hands. When feet start swelling or tingling, I do my best to sit in recliner with feet raised and this seems to help immensely. Thanks for your response!
That is not a silly question. It is one that has been researched and found that lower doses are just as effective in some medications. (maybe all?) Problem is ocologists are only trained at a certain level and can't or wont' go beyond that. Keep asking.
Wishing you all the best,
Cheers, June S.
Hello
I’ve been on Xeloda since April, after the 2 first cycles, dosage was reduced because of bad hand and foot syndrome. Last Tuesday my oncologist told me to do 1,000 twice daily, but one week on (instead of 2) and one week off. Hopefully it’s going to help with neuropathy. Just had a scan and lesions on liver are shrinking (in size and in numbers) so it’s working! Wishing you and your wife all the best,
Hi. I take 4000 mg (2000 x 2) I'm doing ok on it, but a bit sick on the week off. But I tolerate it better than Ibrance. I haven't read much into lower dosage. Interesting. I'm going to take a look. Wishing you both well.
Hello!
I take Xeloda twice a day (1000mg dose) two weeks on, one week off. God bless you and your wife! 💗💗🙏🏻🙏🏻
Linda
So 1000mg twice daily, 2000mg? Thank you for your reply. X
Yes, just finished third cycle. Pet scan is scheduled for September. 🙏🏻🙏🏻💗💗
Good luck. Crossing everything for you. XXX love from us. X
And same back to you! God bless you with peace, love, hope, and strength on this journey!!Linda. 💗💗🙏🏻🙏🏻
Linda, good luck with your scan! Enjoy summer !
Take care
Helen
Thank you so much, Helen! God bless you!! XXOO
I was on capecitabine at 1000mg twice a day doing one week on and one off starting last Sept. At about 6 weeks out the hand and foot syndrome started. I was changed to 500mg in the AM and 1000mg in the PM. At the end of June I was having severe foot pain while walking. The doc at my July 2 appt had me discontinue the drug. The feet are getting better but she is having me stay off for another month. At the next appt Aug 26 I will be starting Piqray. I am feeling uneasy about taking it.
Best of luck to you.
Sharon
1000 morning and 1000 evening after a meal. 2 weeks on and one off. Apart from afternoon fatigue no side effects. Taking Xeloda for about 7 months. CA 15 down. Fewer side effects than Ibrance.
Ask your pharmacist. I don’t think you should break your tablets. Only the person taking the pills should touch the pills. And wash your hands after taking them. Check with your oncologist. This is chemotherapy. Good luck.
Enhertu side effect: pneumonitis (lung inflammation)
Ibrance, Femara , Avastin 
Cyclophosphamide - metronomic chemo/ Good News
PET scans 
what’s next - fulvestrant failed 
