Hello everyone! Finally got my scan results today and unfortunately the afinitor hasn't done it's job. Bone mets are still stable, no new mets but the liver met has increased in size and there is possible lung damage.
Oncologist is adamant that my next treatment has to be intravenous chemo. He can offer me paclitaxel or a place on a trial with Cabazitazel which is being used to treat advanced prostate cancer.
Just wanted to ask if anyone has experience of having cabazitaxel and if so how did it go?
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Julie2233
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Sorry to hear that Julie... Can't help on your treatment sadly, when affinitor proved useless 3 months ago I moved to Faslodex...I am expecting to be moved again but results day would have been Xmas day so it has been moved to 7th Jan...My oncologist suggested there was a few more oral chemo to try before we moved to IV...
As I mentioned to Barb yesterday. Since Ibrance I brace myself for progression every 3 months... Then at least I am ready... But it is nice to know it has worked for some so thanks for sharing 😘
My mets are all in the bone, widespread. I did 20 months of Arimidex with xgeva, followed by 16 months of faslodex with Ibrance and xgeva. After that stopped this June, I tried Affinitor with Exemestance, but it did not work and made my sugar go over 350 triglycerides over 1000. It also raised my liver enzymes. I tried Xeloda for 4 cycles but that did not work either.
I am now on IV Gemzar, hopefully hair will only thin. It is 2 weeks on and one week off. Onc offered several IV chemos but said most people do not lose all their hair with Gemzar., so I decided to try it. Not to sound vain, but my neice has 3 small children and I am not ready to lose my hair yet if I don't need to.
So far the Gemzar has been ok. I did get a port last week to make it easier, this was my 3rd Gemzar, and the port made it so much easier. Hopefully it will work for a while.
I hope it works for me. I think three treatments equals one full one. She is squeezing three in two weeks because I am having cataract surgery Jan 20th second eye. She wants a full treatment before that.
Hi Julie, Sorry you are going through all of this. I was on Ibrance for 9 months before it stopped working. I was switched Verzenio for the increased liver mets which did not work at all. I ended up with much larger lesions and more of them. I was switched to paclitaxel for 6 treatments and the lesions were even larger but the pleural effusion was gone. I am on Xeloda now which is working great. Tumor markers have dropped significantly over the last 6 weeks and side affects are manageable. Hope this information helps.
Thank you that's really interesting to know. The oncologist has said he will consider xeloda after taxol, but I'm concerned about it restricting my ability to walk as I'm a keen walker. Have you experienced any problems with nerve problems?
The taxol gave me neuropathy in my hands and feet as well as a feeling of being scattered mentally and anxious. It took a couple of months for the neuropathy to resolve. The Xeloda causes my feet to hurt and now just starting to peel at the heels. I spend about 8-10 hours on my feet 3-4 days a week. By the end of the day my feet really hurt and need elevation, creams and massage but I still feel better then I did on Taxol. They would probably feel better if I took off a little weight. One day at a time...
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Bone mets only
Jaw Pain
Neuropathy
bc bone Mets spread to skull or brain
