Verzenio and diarrhea

[Lnlc]

Hi-- first time poster here. I have been metastatic for 8 years and am currently on Verzenio. The onc already reduced the dose but I'm still having a horrible time with diarrhea, even with taking 6 lomotil daily. Would like to hear from others with similar experiences and how you've handled the problem. I'm very active and the D truly interferes with my life. Thanks in advance!

[Hidden]

Welcome and sorry to hear you have a problem with mets. Maybe your Oncologist could refer you to a dietician as maybe you are being denied all the Vitamins and Minerals you need for your condition.

I’m on different medication but I had the opposite problem when I first went on my medication but I was referred to a dietician.

Hope you get it sorted out.

Take care

[Hidden]

Sorry to hear about your nasty side effect. I’m sorry I don’t have any advice (I go the other way and get bunged up), but just wanted to congratulate you on your 8 years.

Clare

[Lnlc in reply to Hidden]

Thank you!

[queeneee]

Hello, that sounds debilitating.. I haven't suffered too much with diarrhea on Verzenio. I make my own kefir to improve my stomach flora. It has a wider range of flora than yogurt.. I make it into cacao shakes... lovely.! You can buy it too - which is more expensive. Buy Kefir seeds online to start off the culture.

[Lnlc in reply to queeneee]

Thank you!

[CincinnatiExperience]

Hi,

I had a similar problem when I started on it in July of last year. Give it time! Soon, it disappeared. Let the drug do its work.

Anne

[Lnlc in reply to CincinnatiExperience]

Best news I've heard! Thanks --

[SeattleMom]

Hi, Lnlc,

I have read in several articles that have claimed that Verzenio resolves over time but that treatment with anti-diarrhea meds should be maintained in the meantime. Also, have to be very careful about dehydration. Drink LOTS OF WATER!

Out of curiosity, is Verzenio the only MBC treatment you have received in eight years? If not, what preceded this treatment?

God bless you!

XO Linda

[Lnlc in reply to SeattleMom]

Hi! No, not the first line of treatment. I have bone only mets and have lost count of how many treatments I've had. The one before Verzenio was Piquay, which unfortunately, I had a serious allergic reaction to-- disappointing as it's targeted.

[SeattleMom]

So far, I have bone mets only, too. For that I'm grateful. I've had MBC for almost three years, so your eight years sounds absolutely AMAZING! Would you mind sharing which of your treatments lasted the longest without progression?

God bless you and stay strong!!

XXOO, Linda

[Lnlc in reply to SeattleMom]

Hi Linda....this is going to sound strange, I know, but I don't keep a list of the medications or duration of their treatment as I figure my doctor has that. It's also a way for me not to dwell on the treatment. I know I'm very fortunate in that I've been pain free, active, and except for the rare side effect from the meds, living as usual the past 8 years. I think not remembering the prior treatments is my way of coping: if I don't think about being sick, if I don't feel sick, then I don't realize (in an active way) that I have a life threatening disease. Hope that makes sense! So, I'm afraid I can't provide an answer to your very valid question. Ellen

[SeattleMom in reply to Lnlc]

Hi, Ellen!

That makes a LOT OF SENSE!! Emotional well being is such a key part of our health! What a great reminder!!

XXOO Linda. 💗💗

[ReikoM]

I had problems when I first started Verzenio at 150 mg. Dr. reduced dosage to 100 and then finally 50 mg. I have no problems with the 50 mg twice a day. The 150 was horrible!

I was seeing double and losing alot of weight. I hope you're able to work things out.

[Lnlc]

Eeeeeek. That sounds horrible (and familiar). Yes, the 100mg seems to be treating me better...so far.

[SeattleMom]

Hi, Lnlc!

Just wanted to give you a 👍👍💗💗for your successful treatment of MBC. Do you mind sharing your sequential treatments since diagnosis?

Hope that your D issues have resolved, too. Have you tried immodium?

Blessings! 💗💗

Linda

[SeattleMom in reply to SeattleMom]

Ellen!

So sorry I didn’t catch that I had asked you this same question a month ago! Forgive my DUH moment! God bless you! 💗💗

Linda