Ibrance questions

[Jac-genova]

Is there an alternative to ibrance? What is the longest amount of time someone's been on ibrance? Does it compromise quality of life? Does anyone know of any clinical trials for stage IV metastatic breast cancer, with estrogen positive bone only mets?

[Barbteeth]

Hi there

Ibrance is a relatively ‘new’ drug and prior to that many ladies did well on letrazole only type drugs for many years ....from what I’ve gleaned Ibrance extends progression free survival time before the letrazole ( or faslodex) stops working

It worked for me for approximately 16 months which is about average but there are ladies on here who’ve taken it for five years and it’s still working

The problem is that I don’t know if I would have done just as well on letrazole only if I’d refused the Ibrance...the side effects aren’t nice but I just put up with them as I wanted to do the best I could by taking what the oncologist re commended

Afinitor is similar as is Kisquali...however they all fail eventually and there’s no way you can know how long it will work for you

I’m not much help am I?... if you’re dithering about starting Ibrance I would just go for it....you can always stop if you feel your quality of life is affected...you may be lucky and do well for years....however that you can’t know until you try

I don’t know if any clinical trials

Barb xx

[Jac-genova in reply to Barbteeth]

Thanks Barb!

[Red71]

I think Ibrance right now is the go to treatment for us ladies with bone mets. The one side effect that everyone complains about is tiredness but I think that is all individual, some people go on working, some of us slow down a lot. I think amount of bone mets, prior pain, age, it all makes a difference. I don’t think anyone would recommend a clinical trial right now if you haven’t tried Ibrance. Good luck with your decision. Elaine

[Jac-genova in reply to Red71]

Thanks Elaine! Yeah my mom has 2 bone mets - t2 and l4 regions on lumbar spine

[Phillipians4and6]

Hi I’m ending my 6th cycle of Ibrance/Faslodex. I have pleura and lung Mets. The meds are working really well for me. I have bouts with fatigue and achiness but nothing I can’t deal with. When I first started I did have Blurred vision. Hope this helps.