Been on xeloda past 4 months was working great but now I can tell it's not working . What's next? Anyone trying immune therapy? Anyone see the article about a new drug that is chemo that actually gets to the bond mets which standard chemo can't do for us
Ideas anyone?: Been on xeloda past... - SHARE Metastatic ...
Ideas anyone?
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There isn't immune therapy available except in clinical trials and they are only taking Triple Negative patients. Have you tried radiation for bone mets? Xeloda didn't work for me so I went on Vinolbine for a few years, then Abraxine for a few more years, and then Afinitor with Letrozole (Ibrance wasn't available when I started on Afinitor) which worked for 2 1/2 years.
Now I will be trying Ibrance. I am ER PR positive and HER2 negative. If your cancer is like mine there are lots of treatments available. Hope this helps!
Mary
Like you my trip on Xeloda came to an end after 11 months - liver met grew again. I have now been put on Vinorelbine which comes as weekly doses or metronomic (Monday Wednesday and Friday doses) 2 weeks on and one off. Our medical scheme doesn't pay for the metronomic one so... I am also ER+ and here in South Africa we are not as exposed to trials as in US. Would like to know more about a new chemo - it sounds interesting. However since we have only recently got Ibrance on the medical scheme formularies I wont hold my breath! So far my scheme doesn't even support it as a "normal" medication - it is on the exclusive list!
Hope you come right with your new regime whatever it turns out to be.
Xeloda still working and I feel amazing !! Markers down to 146! My uncle does phone therapy with me and I attribute my thriving to him as well. I live in a new positive being and it has turned my world around !
So glad your Xeloda is still working. I am now on Navelbine into the 3rd cycle. It is a bit less gentle than the Xeloda but hope it keeps my markers going down - on Xeloda they went all over the place! Just had latest bloods and although the blood counts are good the markers are CEA up to 103 and CA125 down to 68 - both were down after 1 cycle so hope this is not a repeat of the Xeloda story for me.
After Xeloda I went on Taxol, when that stopped workiing I tried Ibrance / Faslodex (which never worked for me), then was on Doxorubicin (which has a lifetime maximum, which for me was six doses three weeks apart). Currently I am on Eribulin. CA 27.29 is down to 39 and CA15-3 is down to 57. So glad it is working but the neuropathy has gotten substantially worse so I'm sure I'll be switching soon. Next chemo planned will be Gemzitabean (sp?).
I am ER/PR+, HER2-