antidepressant recommendations? - Restless Legs Syn...

Restless Legs Syndrome

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antidepressant recommendations?

Islay9 profile image
18 Replies

Looking for anti depressant recommendations please.

I’m in the UK. The RLS UK website lists Trazodone and Bupropion as being safe for RLS but the BNF doesn’t list Bupropion for depression and Trazodone is not going to be great with Pregabalin and Dihydrocodeine due to the sedative affects.

Are there any others that might be ok that anyone knows of?

Thanks 🙏

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Islay9 profile image
Islay9
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18 Replies
SueJohnson profile image
SueJohnson

Moclobemide or Vortioxetine (trintellix, Brintellix) is on RLS-UK not safe list - however some people find it is safe

Islay9 profile image
Islay9 in reply toSueJohnson

Thanks Sue I’ll have a look at those.

Eryl profile image
Eryl

There's a good chance that you can end depression without meds by changing your diet. youtu.be/w76HgPmnwhU?si=3ue...

David7 profile image
David7

BUPROPION ( Wellbutrin) works well for depression and won't cause additional problems with RLS.

Islay9 profile image
Islay9 in reply toDavid7

I agree this seems to be a good option, the problem is it’s not listed as an antidepressant on the BNF/NICE guidelines so not sure if they’ll be happy prescribing it?

Do you know if any evidence I could direct them to?

RLS1952 profile image
RLS1952 in reply toDavid7

I thought it put weight on?

David7 profile image
David7

Very well known anti- depressant.

Wellbutrin, anti- depressant.
Islay9 profile image
Islay9 in reply toDavid7

Thank you. Unfortunately not licensed for depression in the UK.

grandma_of_7 profile image
grandma_of_7

bupropion is totally an anti depressant - it isn’t used for anything else!. I use it, 300mgs, but it did stir up the RLS a bit, so dr increased the methadone.

grandma_of_7 profile image
grandma_of_7 in reply tograndma_of_7

Is your ferritin over 100?

Islay9 profile image
Islay9 in reply tograndma_of_7

No but I’m on iron therapy to get it up there.

grandma_of_7 profile image
grandma_of_7 in reply toIslay9

Good! It does the trick for a lot of us!

Islay9 profile image
Islay9 in reply tograndma_of_7

thank you, Unfortunately not licensed for depression in the UK.

grandma_of_7 profile image
grandma_of_7

I'm having trouble seeing which posts I'm responding to, trying to learn how to navigate this group!

SueJohnson profile image
SueJohnson in reply tograndma_of_7

If you click reply under the post then you are responding to that post. For example I clicked reply under your post saying you were having trouble seeing which posts.

grandma_of_7 profile image
grandma_of_7 in reply toSueJohnson

Yes, I see that. Thanks so much for helping me! But I don't get how to stroll down to see other posts and replies. I wish it was a little more like Facebook! I'm 70 and so I think my age affects my abilities here! but you probably figured that out from my name, grandma of 7!

Islay9 profile image
Islay9 in reply tograndma_of_7

I have the same problem with this page!

If you go to the very top of this page it says “posts” and you can click there to see more posts.

Replies to posts are quite far down past some other stuff on that post.

grandma_of_7 profile image
grandma_of_7 in reply toIslay9

Great, good to know! I just copied and pasted what you wrote so I can try it tomorrow, thanks

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