Obstructive Sleep Apnea (OSA) and RLS - article

[PoorRichard]

My recent sleep study concluded I have mild-to-moderate obstructive sleep apnea (OSA), in addition to RLS, of course. It turns out there is a higher than average prevalence of RLS in OSA patients (~8%), although they are not causally related. I am awaiting delivery and fitting of a CPAP machine (there is currently a global shortage due to one manufacturer's recall and the global computer chip shortage). In the meantime my chief of research (wife) found this very informative article from the European Respiratory Review. It presents a good discussion of both conditions. I only wish their Conclusion section came down more strongly against dopamine agonists - they underplay the risk of augmentation. Nevertheless, if anyone is looking for a thorough discussion of RLS comorbid with OSA this is an excellent resource.

err.ersjournals.com/content...

[DicCarlson]

Thanks, that's a nice review of the 2 conditions.

[HappyGreenBean]

I'm glad you've found this out and that you're likely to receive treatment soon. I hope for your sake, very soon.

Are you in the US or UK?

[PoorRichard in reply to HappyGreenBean]

US. The global shortage of CPAP machines is preventing my equipment delivery. Sigh. What an era.

[HappyGreenBean in reply to PoorRichard]

Ha, yes, what a time to be alive! You can sometimes pick them up for a good price second hand and then you can have your Dr help you set it up. Obviously, that's up to you and your Dr. But, I know a few people who have done this. I wish you the best of luck.

[Pte82]

PoorRichard this ncbi attachment about OSA contains information that, indirectly, may benefit RLS as well. An advantage for both is utilizing thiamine that is able to pass through the blood brain barrier at higher levels than water soluble vitamin B1 forms and also higher absorbed levels in the body. . fat soluble thiamine forms TTFD and sulbutiamine. When activated by a magnesium form like theonate that also can pass through the blood brain barrier they offer, along with other B vitamins, a critical component for dopamine activity and dopamine receptors. A thiamine deficiency can inhibit lactic acid clearing from muscles leading to a condition contributing to RLS.

ncbi.nlm.nih.gov/pmc/articl...

mybiohack.com/blog/all-ways...

men-elite.com/2017/09/01/vi...