"Weight loss drug could ease sleep apnoea in people with obesity, study says"

[ChrisColumbus]

As RLS and obstructive sleep apnoea are often linked, this story about research concluding that tirzepatide (Mounjaro, Zepbound) could become the first pharmaceutical treatment for OSA may be of interest:

theguardian.com/society/art...

[Eryl]

RLS, sleep aponea and obesity are all linked to bad diet.

[Gmc54 in reply to Eryl]

Rls is not always related to a bad diet.

[Eryl in reply to Gmc54]

No, bout in combination with the other problems it is highly likely.

[Lluvinlife in reply to Eryl]

I am not obese with a BMI right in the middle of the healthy zone, practice intermittent fasting combined with a whole foods diet, exercise daily (rock climbing, running and cycling) yet I have mild sleep apnea and RLS. Sometimes these things have genetic connections and come with age regardless of health efforts. I suspect if I were obese with a poor diet my apnea and RLS would be much worse.

[Eryl in reply to Lluvinlife]

It's probably all the excersise that keeps you from getting obese.

[Lluvinlife in reply to Eryl]

I think it is the intermittent fasting actually but that is not the point. my point is that we cannot assume those with sleep apnea and RLS are obese with a poor diet

[Eryl in reply to Lluvinlife]

The original post specifically refers to "sleep apnoea in people with obesity" which is usually the result of eating a poor diet.

[ChrisColumbus in reply to Eryl]

A poor diet and/or excessive eating *may*of course be linked to all sorts of medical conditions. On the other hand, there are plenty of people who suffer from one or more of these conditions - even in some cases obesity - who eat a perfectly good diet and do not eat to excess. RLS is only sometimes related to diet.

[ChrisColumbus in reply to Eryl]

While the research did specifically look at OSA in obese individuals, as Dr Sanjay Patel writes in his editorial acompanying the research: "Excess weight is the most important risk factor for obstructive sleep apnea; it is responsible for approximately 60% of moderate-to-severe cases of obstructive sleep apnea in the United States", which leaves 40% of such cases where excess weight is NOT responsible for moderate to severe OSA.

[Eryl in reply to ChrisColumbus]

No, we have the TOFI types who store the fat on the inside. In both cases inflammation is also a major problem contributing to. RLS, OSA cardiovascular disease, mental health problems, athsma, copd and a host of other chronic diseases.