Help with medication. Targin Or Palexia - Restless Legs Syn...

Restless Legs Syndrome

22,014 members15,803 posts

Help with medication. Targin Or Palexia

Shir_11 profile image
2 Replies

Taking Targin has helped me get a good night sleep but the side effects such as sweats, dry mouth and gut ache wants me to try something else. A friend takes Palexia and Lyrica together which helps her. Would Palexia have the same effect as Targin. Because of this corona virus I have to have a phone visit with GP on Thursday and on my last Of the 2 week trial of Targin. I need to do my research before his call. Thank you

Written by
Shir_11 profile image
Shir_11
To view profiles and participate in discussions please or .
Read more about...
2 Replies

Hi Shir

I see you have already tried:

Repreve (ropinirole)

Sifrol (pramipexole)

Tramal (tramadol) and

Targin (oxycodone/naloxone)

Your GP may suggest continuing with the Targin and seeing if the side effects lessen the longer you take it.

If however the symptoms are unbearable, you could try Lyrica (pregabalin) on its own. Many sleep specialists/ neurologists in Australia prescribe this in the first instance for RLS.

Your GP should be aware of this. If not, it may be worth seeking out a sleep specialist who is across first line treatments.

It's usually worth trying a medication on its own before combining medications as when medications are combined in the first instance, it's difficult to establish which medication if any, are working.

People on this forum say that it takes about 3 weeks for Lyrica (pregabalin) to have optimal effect. Personally I found it to be effective straight away however as we all know, responses vary between individuals.

Shir_11 profile image
Shir_11 in reply to

I did try the Lyrica on its own after 2 weeks on Targin. Nearly sent me crazy until I took the Targin late that night. Maybe my doctor will tell me to take Targin and Lyrica together for a few weeks.

Not what you're looking for?

You may also like...

Help please

Hi, Im new to the forum hoping to get some ideas and advice. I’m was dx severe rls and periodic...

documenting changes

so I had been struggling with a flare up in my rls since starting HRT 2 months ago and although the...

Severe RLS in Las Vegas, NV

Hello....my GP doctors have been treating my RLS with ropinirole (augmentation), pramipexole...

Would oral iron be useful given my Iron levels (in description)?

I have RLS and got some bloodwork done. The following came up: IRON , SERUM 91.0 µg/dL TOTAL IRON...

Gabapentin

Hi, I have now been off pramipexole for six week. I initially started on pregablin as the...