Was doing my own research on RLS as my GP seemed to know very little about the condition. Have suffered for many years but got worse after my Knee Replacement.
What I found was interesting. In my case, one of my conditions being I suffer from Migraines. I have been on the drug Amitriptyline for 40 years prescribed by my neurologist.It happened to rank in the top 10 drugs NOT to take if you have RLS. Leaves me with a dilemma. I was also found to be low on IRON & MAGNESIUM, 2 contributing factors to RLS.
Definitely do not want to take any form of Narcotic so am seeking out natural products and changing or coming off Amitriptyline. Hope this helps
Written by
jcasey
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Hi i have been on amitriptyline since 2004, was never told it it is bad for rls! I too want to get off as many meds as i possibly can, i have only found oramorph to help with the rls, i don't take very much , 2.5 -5ml in the evening's when the rls is usually at its worst ,
I am having magnesium baths ,Clary sage baths, and sometimes massage with the oil ,mixing it in a base oil (almomd) , this also helps . (But in case anyone who is pregnant is reading ,DO NOT USE CLARY SAGE IN PREGNANCY :)) had to just add that ,as there may be women pregnant that have the restless legs .
It's best to ask your Dr first ,about any med interactions between herbal and pharma , but it's definitely worth a try ,doesn't work for everyone ,i too am finding it hit and miss, hope you find releif
Iron can be the key - it was for me. I'm on no drugs after discovering an Iron deficiency. Use Ferrous Bisglycinate Chelate. hopkinsmedicine.org/neurolo...
It is a patented chelete - binding to an amino acid for better absorption. Ferrochel Iron Chelate - Ferrochel® Iron Chelate is a potent iron supplement that is extremely well tolerated by the gastrointestinal system. Ferrochel® is a premier chelate from Albion Advanced Nutrition. It is safe for use by pregnant and lactating women, teenagers, and adults. Unlike most iron preparations, it will not result in constipation or gastric upset. This amino acid chelated iron has very high absorption.
Ferrochel® is a patented iron in the form of iron bis-glycinate, providing 27 mg of elemental iron (150% of RDA). Unlike common forms of supplemental iron, this form of iron carries no electrical charge, making it easier to absorb and less likely to block the absorption of other nutrients, such as vitamin E, ascorbic acid, and calcium. Because Ferrochel® is a neutral, fully-reacted molecule, it does not break down in stomach acid and is delivered intact to the intestine, where it is easily absorbed. Inorganic iron supplements, such as ferrous sulfate, have low bioavailability and often produce unpleasant gastrointestinal side effects, such as nausea, constipation and gastric upset. The form of iron in Ferrochel® gives clinicians a better alternative.
Doctor prescribed Amitriptyline too when I went to him with my increasingly bad RLS. It didn't help, so he prescribed 2 Pramipexole 0.088mg every evening a couple of hours before I go to bed, and I have found that this really helps. It works in a completely different way to Amitriptyline.
In my case, I have been on Amitriptyline for 40 yrs for migraines. RLS increasingly intolerable for many years now. The research I have done myself shows Amitriptyline to be one of the worse drugs for causing RLS. Thanks for the info.
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New Member. Annjulia aged 70 
Channel 5 RLS Documentary
Does anyone take amitriptyline and pramepexole and have effects 
