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Restless Legs Syndrome

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Antihistamines

Bejwo50 profile image
15 Replies

Do Antihistamines make rls worse ?

My mum takes cetrizine daily due to allergies and I'm wondering if they make the pain worse because today she took one in the morning and accidentally took another in the evening and her rls is kicking in.

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Bejwo50 profile image
Bejwo50
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15 Replies
Pippins2 profile image
Pippins2

Yes , the only safe antihistamines to take if you have RLS are Claritin / Clarytin and Allegra x

Madlegs1 profile image
Madlegs1 in reply toPippins2

Zyrtec (spelling?) may also be ok.

I take Claritin without ill effects.

Pippins2 profile image
Pippins2 in reply toMadlegs1

Madlegs just for your ever growing RLS knowledge Zyrtec is just brand name for Cetrizine . x

Madlegs1 profile image
Madlegs1 in reply toPippins2

Thanks- I was getting that info from the Health Unlocked page , which is saying that cetrizine may be ok for rls . It is the same 2nd generation antihistamines as Claritin.

So - back to square 1 for Bejwo's Mum.😢

Pippins2 profile image
Pippins2 in reply toMadlegs1

Further research shows that some arein fact able to take Zyrtec without problems . It is the Zyrtec D that must be avoided . Thanks Madlegs for furthering my RLS knowledge lol

All the best , be careful of your back doing the Can Can (wink )x

Madlegs1 profile image
Madlegs1 in reply toPippins2

😁😎🎅

Jose651 profile image
Jose651

Yes, definitely for me.

J 🍀

Bejwo50 profile image
Bejwo50

Great advice, thanks everyone. will have a look into changing her allergy medicine.

Docholiday1 profile image
Docholiday1

Yes they do in me much worse and it is every antihistamine I have tried .

Pippins2 profile image
Pippins2

Also be aware of Zyrtec D as it contains an added ingredient to make you drowsy but will send RLS nuts . (Pseudoephedrine ) x

Grammieof4 profile image
Grammieof4 in reply toPippins2

I thought the "D" is for decongestant (pseudophed) is a non drowsy formula...

CatherineABQ profile image
CatherineABQ

Yes. I do t take any oral antihistamines and instead use a prescription antihistamine nasal spray and anti-allergy eye drops as needed.

daisyw profile image
daisyw

My rls has been pretty bad lately and my Doc has got me on Fexofenadine Hydrochloride180mg Antihistamines. Where do they come in the great table of help or hinder please?

ebn513 profile image
ebn513

Antihistamines block the dopamine, just like they block histamines that cause allergies. Therefore your body is signaled to produce EVEN MORE dopamine, therefore, legs are worse. (At least, this is my understanding from the way my doc explained it). :-)

Bejwo50 profile image
Bejwo50 in reply toebn513

Thanks ebn513.

That makes sense

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