hi everyone

[Spaniard61]

I am a Spanish citizen martied to another man. I have just been diagnosed with prostate cancer, I feel very fortunate to have a Gleason 6. I am looking for communities to receive and give support an information. I am learning a lot from other Patients. First I thought of HIFU but a doctor told me it was not a good option for me as the cancer cells are near the the urethra, so electroporation would be ok, I would like to know if anyone had had this treatment and hear his experience.

[Tall_Allen]

E. Irreversible Electroporation/NanoKnife (IRE):

In a study of focal IRE, which is largely a non-thermal form of ablation, 4/25 patients (16%) were found to have residual cancer in the ablation zone. In another study that used mpMRI to detect residual cancer up to one year after treatment, 9/30 patients (30%) were found to have residual cancer in the ablation zone. Colletini et al reported in-field treatment failures by 18% of low and intermediate-risk patients detected via mpMRI-targeted biopsy after 6 months. Valerio et al. reported that 6/34 patients (18%) had residual disease. Guenther et al. reported that the recurrence rate at 5 years was 5.6% for Gleason 6, 14.6% for Gleason 7, and 39.5% for Gleason 8–10. Gielchinsky and Lev-Cohain reported that 4/13 patients had biopsy-detected recurrence. Zhang et al. reported that 6-months after focal IRE, 46% of low- and intermediate-risk cancer still had biopsy-detected cancer outside of the ablation zone and 17% still had cancer inside the ablation zone.

prostatecancer.news/2016/12...

You should also be aware that IRE entails full anesthesia with stopping the heart and a heart/lung machine.