biopsy after orgovyx

[Nashman]

does anyone know how long you should wait after taking Orgovyx to get a biopsy? I can't find any information about this on the Orgovyx website and the patient information number doesn't seem to work.

[Tall_Allen]

There's no profile. Why are you taking Orgovyx before you've had a biopsy?

[Nashman in reply to Tall_Allen]

Thanks for the reply. I'm sorry I used to have a profile but I could not find it, so I registered again. I had a biopsy in Feb 2023 with gleason score 4+3=7 report from the local lab here and a second opinion from Johns Hopkins. I had insurance problems, so in August 2023 I was advised to start taking Orgovyx until medicare was effective Nov. 1. I took the Orgovyx from August 30 2023 until Dec. 6 2023. After I got medicare I was able to change doctors, and I obtained two more pathology opinions, both 3+4=7 instead of 4+3=7. So the new urologist ordered a new MRI and biopsy on Feb 21 2024, which found no cancer, and no gleason score. Now I am being told that I had the biopsy too soon after the orgovyx and the results are not valid. I would like to know what the drug manufacturer recommends but I cannot find the information anywhere. My PSA increased from 4.5 when I had the 2nd biopsy in Feb to 7.7 now.

[Tall_Allen in reply to Nashman]

That is idiotic that he gave you another biopsy. Whatever Johns Hopkins said is definitive. You don't need another biopsy.

[Nashman in reply to Tall_Allen]

I agree it is idiotic but I have to figure out what to do. The pathology report from Johns Hopkins is from my Feb 2023 biopsy and it says gleason 4+3=7, but two other pathologists reviewed the same slides and said gleason 3+4=7. The pathology report from my Feb 2024 biopsy is from Vanderbilt University and it says no cancer detected. Is that because it was too soon after the orgovyx? Should I have a third biopsy since my PSA has risen?

[Tall_Allen in reply to Nashman]

As I said, "Whatever Johns Hopkins said is definitive. You don't need another biopsy." I don't know how to say it more clearly.

[Nashman in reply to Tall_Allen]

I do not have as much confidence in Johns Hopkins as you do. The pathologist that signed my report left recently because of "misconduct"

[Tall_Allen in reply to Nashman]

The way he treats his employees doesn't detract from Epstein and his lab being the gold standard.